schliessen

Filtern

 

Bibliotheken

Serotonin transporter polymorphism moderates the effects of caregiver intrusiveness on ADHD symptoms among institutionalized preschoolers.

To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s00787-016-0890-x Byline: Joana Baptista (1), Jay Belsky (2), Ana Mesquita (1), Isabel Soares (1) Keywords: Institutionalized children; ADHD; Caregiver intrusiveness; S... Full description

Journal Title: European child & adolescent psychiatry March 2017, Vol.26(3), pp.303-313
Main Author: Baptista, Joana
Other Authors: Belsky, Jay , Mesquita, Ana , Soares, Isabel
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1435-165X ; DOI: 10.1007/s00787-016-0890-x
Link: http://search.proquest.com/docview/1826729214/?pq-origsite=primo
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: proquest1826729214
title: Serotonin transporter polymorphism moderates the effects of caregiver intrusiveness on ADHD symptoms among institutionalized preschoolers.
format: Article
creator:
  • Baptista, Joana
  • Belsky, Jay
  • Mesquita, Ana
  • Soares, Isabel
subjects:
  • Adolescent–Etiology
  • Attention Deficit Disorder With Hyperactivity–Genetics
  • Caregivers–Psychology
  • Child–Psychology
  • Child, Institutionalized–Psychology
  • Child, Preschool–Genetics
  • Female–Genetics
  • Gene-Environment Interaction–Metabolism
  • Genetic Predisposition to Disease–Physiology
  • Humans–Physiology
  • Male–Physiology
  • Mental Health–Physiology
  • Polymorphism, Genetic–Physiology
  • Serotonin Plasma Membrane Transport Proteins–Physiology
  • Slc6a4 Protein, Human
  • Serotonin Plasma Membrane Transport Proteins
  • ADHD
  • Caregiver Intrusiveness
  • Differential Susceptibility
  • Institutionalized Children
ispartof: European child & adolescent psychiatry, March 2017, Vol.26(3), pp.303-313
description: To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s00787-016-0890-x Byline: Joana Baptista (1), Jay Belsky (2), Ana Mesquita (1), Isabel Soares (1) Keywords: Institutionalized children; ADHD; Caregiver intrusiveness; Serotonin transporter polymorphism; Differential susceptibility Abstract: Research consistently chronicles a variety of mental health difficulties that plague institutionally reared children, including attention-deficit/hyperactivity disorder (ADHD), even if not all institutionalized children evince such problems. In seeking to extend work in this area, this research on gene x environment (GXE) interplay investigated whether the effect of the quality of institutional care--most notably, caregiver intrusiveness--on ADHD symptoms is moderated by the serotonin transporter (5-HTTLPR) polymorphism. One hundred and twenty-seven institutionalized preschoolers were evaluated using the Child Behavior Checklist. Caregiver-rated attention problems and hyperactivity were unrelated to both 5-HTTLPR polymorphism and caregiver intrusiveness. A significant GXE effect, independent of age at placement or duration of institutionalization, emerged, however, consistent with the differential-susceptibility hypothesis: s/s homozygotes manifest the most and least ADHD symptoms when they experienced, respectively, more and less intrusive caregiving. These results provide new insight into the reasons why some institutionalized children, but not others, exhibit ADHD symptoms. Author Affiliation: (1) Psychology Research Center-CIPsi, School of Psychology, University of Minho, Campus de Gualtar, 4710-050, Braga, Portugal (2) University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA Article History: Registration Date: 09/07/2016 Received Date: 09/10/2015 Accepted Date: 09/07/2016 Online Date: 18/07/2016
language: eng
source:
identifier: E-ISSN: 1435-165X ; DOI: 10.1007/s00787-016-0890-x
fulltext: fulltext
issn:
  • 1435165X
  • 1435-165X
url: Link


@attributes
ID1134167245
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid1826729214
sourceidproquest
recordidTN_proquest1826729214
sourcesystemPC
pqid1826729214
galeid482423962
display
typearticle
titleSerotonin transporter polymorphism moderates the effects of caregiver intrusiveness on ADHD symptoms among institutionalized preschoolers.
creatorBaptista, Joana ; Belsky, Jay ; Mesquita, Ana ; Soares, Isabel
contributorBaptista, Joana (correspondence author) ; Baptista, Joana (record owner)
ispartofEuropean child & adolescent psychiatry, March 2017, Vol.26(3), pp.303-313
identifierE-ISSN: 1435-165X ; DOI: 10.1007/s00787-016-0890-x
subjectAdolescent–Etiology ; Attention Deficit Disorder With Hyperactivity–Genetics ; Caregivers–Psychology ; Child–Psychology ; Child, Institutionalized–Psychology ; Child, Preschool–Genetics ; Female–Genetics ; Gene-Environment Interaction–Metabolism ; Genetic Predisposition to Disease–Physiology ; Humans–Physiology ; Male–Physiology ; Mental Health–Physiology ; Polymorphism, Genetic–Physiology ; Serotonin Plasma Membrane Transport Proteins–Physiology ; Slc6a4 Protein, Human ; Serotonin Plasma Membrane Transport Proteins ; ADHD ; Caregiver Intrusiveness ; Differential Susceptibility ; Institutionalized Children
languageeng
source
descriptionTo access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s00787-016-0890-x Byline: Joana Baptista (1), Jay Belsky (2), Ana Mesquita (1), Isabel Soares (1) Keywords: Institutionalized children; ADHD; Caregiver intrusiveness; Serotonin transporter polymorphism; Differential susceptibility Abstract: Research consistently chronicles a variety of mental health difficulties that plague institutionally reared children, including attention-deficit/hyperactivity disorder (ADHD), even if not all institutionalized children evince such problems. In seeking to extend work in this area, this research on gene x environment (GXE) interplay investigated whether the effect of the quality of institutional care--most notably, caregiver intrusiveness--on ADHD symptoms is moderated by the serotonin transporter (5-HTTLPR) polymorphism. One hundred and twenty-seven institutionalized preschoolers were evaluated using the Child Behavior Checklist. Caregiver-rated attention problems and hyperactivity were unrelated to both 5-HTTLPR polymorphism and caregiver intrusiveness. A significant GXE effect, independent of age at placement or duration of institutionalization, emerged, however, consistent with the differential-susceptibility hypothesis: s/s homozygotes manifest the most and least ADHD symptoms when they experienced, respectively, more and less intrusive caregiving. These results provide new insight into the reasons why some institutionalized children, but not others, exhibit ADHD symptoms. Author Affiliation: (1) Psychology Research Center-CIPsi, School of Psychology, University of Minho, Campus de Gualtar, 4710-050, Braga, Portugal (2) University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA Article History: Registration Date: 09/07/2016 Received Date: 09/10/2015 Accepted Date: 09/07/2016 Online Date: 18/07/2016
version6
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
backlink$$Uhttp://search.proquest.com/docview/1826729214/?pq-origsite=primo$$EView_record_in_ProQuest_(subscribers_only)
search
creatorcontrib
0Baptista, Joana
1Belsky, Jay
2Mesquita, Ana
3Soares, Isabel
titleSerotonin transporter polymorphism moderates the effects of caregiver intrusiveness on ADHD symptoms among institutionalized preschoolers.
subject
0Adolescent–Etiology
1Attention Deficit Disorder With Hyperactivity–Genetics
2Caregivers–Psychology
3Child–Psychology
4Child, Institutionalized–Psychology
5Child, Preschool–Genetics
6Female–Genetics
7Gene-Environment Interaction–Metabolism
8Genetic Predisposition to Disease–Physiology
9Humans–Physiology
10Male–Physiology
11Mental Health–Physiology
12Polymorphism, Genetic–Physiology
13Serotonin Plasma Membrane Transport Proteins–Physiology
14Slc6a4 Protein, Human
15Serotonin Plasma Membrane Transport Proteins
16ADHD
17Caregiver Intrusiveness
18Differential Susceptibility
19Institutionalized Children
20Caregiver intrusiveness
21Differential susceptibility
22Institutionalized children
23Serotonin transporter polymorphism
general
0English
110.1007/s00787-016-0890-x
2MEDLINE (ProQuest)
3ProQuest Biological Science Collection
4ProQuest Natural Science Collection
5ProQuest SciTech Collection
6Biological Science Database
7Natural Science Collection
8SciTech Premium Collection
9Health Research Premium Collection
10Health Research Premium Collection (Alumni edition)
11Biological Science Index (ProQuest)
sourceidproquest
recordidproquest1826729214
issn
01435165X
11435-165X
rsrctypearticle
creationdate2017
addtitleEuropean child & adolescent psychiatry
searchscope
01007527
11007944
21009130
310000004
410000038
510000050
610000120
710000159
810000238
910000253
1010000260
1110000270
1210000271
1310000302
1410000350
15proquest
scope
01007527
11007944
21009130
310000004
410000038
510000050
610000120
710000159
810000238
910000253
1010000260
1110000270
1210000271
1310000302
1410000350
15proquest
lsr43
01007527false
11007944false
21009130false
310000004false
410000038false
510000050false
610000120false
710000159false
810000238false
910000253false
1010000260false
1110000270false
1210000271false
1310000302false
1410000350false
contributorBaptista, Joana
startdate20170301
enddate20170301
citationpf 303 pt 313 vol 26 issue 3
lsr30VSR-Enriched:[galeid, issn, description, pqid]
sort
titleSerotonin transporter polymorphism moderates the effects of caregiver intrusiveness on ADHD symptoms among institutionalized preschoolers.
authorBaptista, Joana ; Belsky, Jay ; Mesquita, Ana ; Soares, Isabel
creationdate20170301
lso0120170301
facets
frbrgroupid8598509375411354383
frbrtype5
newrecords20181218
languageeng
creationdate2017
topic
0Adolescent–Etiology
1Attention Deficit Disorder With Hyperactivity–Genetics
2Caregivers–Psychology
3Child–Psychology
4Child, Institutionalized–Psychology
5Child, Preschool–Genetics
6Female–Genetics
7Gene-Environment Interaction–Metabolism
8Genetic Predisposition to Disease–Physiology
9Humans–Physiology
10Male–Physiology
11Mental Health–Physiology
12Polymorphism, Genetic–Physiology
13Serotonin Plasma Membrane Transport Proteins–Physiology
14Slc6a4 Protein, Human
15Serotonin Plasma Membrane Transport Proteins
16ADHD
17Caregiver Intrusiveness
18Differential Susceptibility
19Institutionalized Children
collection
0MEDLINE (ProQuest)
1ProQuest Biological Science Collection
2ProQuest Natural Science Collection
3ProQuest SciTech Collection
4Biological Science Database
5Natural Science Collection
6SciTech Premium Collection
7Health Research Premium Collection
8Health Research Premium Collection (Alumni edition)
9Biological Science Index (ProQuest)
prefilterarticles
rsrctypearticles
creatorcontrib
0Baptista, Joana
1Belsky, Jay
2Mesquita, Ana
3Soares, Isabel
jtitleEuropean child & adolescent psychiatry
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Baptista
1Belsky
2Mesquita
3Soares
aufirst
0Joana
1Jay
2Ana
3Isabel
au
0Baptista, Joana
1Belsky, Jay
2Mesquita, Ana
3Soares, Isabel
addauBaptista, Joana
atitleSerotonin transporter polymorphism moderates the effects of caregiver intrusiveness on ADHD symptoms among institutionalized preschoolers.
jtitleEuropean child & adolescent psychiatry
risdate20170301
volume26
issue3
spage303
epage313
pages303-313
eissn1435-165X
formatjournal
genrearticle
ristypeJOUR
doi10.1007/s00787-016-0890-x
urlhttp://search.proquest.com/docview/1826729214/
issn10188827
date2017-03-01