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A dual-functional supramolecular hydrogel based on a spiropyran-galactose conjugate for target-mediated and light-controlled delivery of microRNA into cells

A supramolecular hydrogel formed by spiropyran conjugated galactose was developed for light-controlled release of miR-122 and target-mediated delivery of the miRNA into HepG2 cells cultured on top of the gel.

Journal Title: Chemical Communications: Chem Comm October 2016, Vol.52(84), pp.12517-12520
Main Author: Xiao, Xiao
Other Authors: Hu, Jing , Wang, Xingxing , Huang, Lei , Chen, Yingjie , Wang, Wei , Li, Jinbo , Zhang, Yan
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 1359-7345 ; E-ISSN: 1364-548X ; DOI: 10.1039/c6cc07386g
Link: http://search.proquest.com/docview/1845814947/?pq-origsite=primo
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recordid: proquest1845814947
title: A dual-functional supramolecular hydrogel based on a spiropyran-galactose conjugate for target-mediated and light-controlled delivery of microRNA into cells
format: Article
creator:
  • Xiao, Xiao
  • Hu, Jing
  • Wang, Xingxing
  • Huang, Lei
  • Chen, Yingjie
  • Wang, Wei
  • Li, Jinbo
  • Zhang, Yan
subjects:
  • Galactose
  • Ribonucleic Acids
  • Spiropyrans
  • Hydrogels
  • Conjugates
  • Miscellaneous Sciences (So)
  • Chemical and Electrochemical Properties (MD)
  • Chemical and Electrochemical Properties (Ep)
  • Chemical and Electrochemical Properties (Ed)
  • Chemical and Electrochemical Properties (EC)
ispartof: Chemical Communications: Chem Comm, October 2016, Vol.52(84), pp.12517-12520
description: A supramolecular hydrogel formed by spiropyran conjugated galactose was developed for light-controlled release of miR-122 and target-mediated delivery of the miRNA into HepG2 cells cultured on top of the gel.
language: eng
source:
identifier: ISSN: 1359-7345 ; E-ISSN: 1364-548X ; DOI: 10.1039/c6cc07386g
fulltext: fulltext
issn:
  • 13597345
  • 1359-7345
  • 1364548X
  • 1364-548X
url: Link


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abstractA supramolecular hydrogel formed by spiropyran conjugated galactose was developed for light-controlled release of miR-122 and target-mediated delivery of the miRNA into HepG2 cells cultured on top of the gel.
doi10.1039/c6cc07386g
urlhttp://search.proquest.com/docview/1845814947/
date2016-10-01