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Photo-clickable microRNA for in situ fluorescence labeling and imaging of microRNA in living cells

A photo-clickable microRNA whose fluorescence was able to be turned on by mild light irradiation was constructed and the in situ fluorescence turn-on of the photo-clickable microRNA-122 in living cells was demonstrated by light irradiation with spatial and temporal resolution.

Journal Title: Chemical Communications: Chem Comm June 2017, Vol.53(48), pp.6452-6455
Main Author: Huang, Lei
Other Authors: Chen, Yingjie , Chen, Lei , Xiao, Xiao , Wang, Xingxing , Li, Jinbo , Zhang, Yan
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 1359-7345 ; E-ISSN: 1364-548X ; DOI: 10.1039/c7cc03328a
Link: http://search.proquest.com/docview/1915323849/?pq-origsite=primo
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recordid: proquest1915323849
title: Photo-clickable microRNA for in situ fluorescence labeling and imaging of microRNA in living cells
format: Article
creator:
  • Huang, Lei
  • Chen, Yingjie
  • Chen, Lei
  • Xiao, Xiao
  • Wang, Xingxing
  • Li, Jinbo
  • Zhang, Yan
subjects:
  • Light Irradiation
  • Cells (Biology)
  • Fluorescence
  • Labels
  • Ribonucleic Acids
  • Temporal Resolution
  • Imaging
  • Marking
  • Miscellaneous Sciences (So)
  • Chemical and Electrochemical Properties (MD)
  • Chemical and Electrochemical Properties (Ep)
  • Chemical and Electrochemical Properties (Ed)
  • Chemical and Electrochemical Properties (EC)
ispartof: Chemical Communications: Chem Comm, June 2017, Vol.53(48), pp.6452-6455
description: A photo-clickable microRNA whose fluorescence was able to be turned on by mild light irradiation was constructed and the in situ fluorescence turn-on of the photo-clickable microRNA-122 in living cells was demonstrated by light irradiation with spatial and temporal resolution.
language: eng
source:
identifier: ISSN: 1359-7345 ; E-ISSN: 1364-548X ; DOI: 10.1039/c7cc03328a
fulltext: fulltext
issn:
  • 13597345
  • 1359-7345
  • 1364548X
  • 1364-548X
url: Link


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titlePhoto-clickable microRNA for in situ fluorescence labeling and imaging of microRNA in living cells
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subjectLight Irradiation ; Cells (Biology) ; Fluorescence ; Labels ; Ribonucleic Acids ; Temporal Resolution ; Imaging ; Marking ; Miscellaneous Sciences (So) ; Chemical and Electrochemical Properties (MD) ; Chemical and Electrochemical Properties (Ep) ; Chemical and Electrochemical Properties (Ed) ; Chemical and Electrochemical Properties (EC)
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abstractA photo-clickable microRNA whose fluorescence was able to be turned on by mild light irradiation was constructed and the in situ fluorescence turn-on of the photo-clickable microRNA-122 in living cells was demonstrated by light irradiation with spatial and temporal resolution.
doi10.1039/c7cc03328a
urlhttp://search.proquest.com/docview/1915323849/
date2017-06-01