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Lipid changes 8 years post gastric bypass in adolescents with severe obesity (FABS-5+ study)

Objective:Severe obesity in adolescents is increasing and few effective treatments exist. Bariatric surgery is one option, but the extent to which surgery influences cardiovascular risk factors over time in youth is not clear. We hypothesized that Roux-en Y gastric bypass (RYGB) would be associated... Full description

Journal Title: International Journal of Obesity Oct 2017, Vol.41(10), pp.1579-1584
Main Author: Shah, A
Other Authors: Jenkins, T , Gao, Z , Daniels, S , Urbina, E , Kirk, S , Siegel, R , Inge, T
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 03070565 ; E-ISSN: 14765497 ; DOI: 10.1038/ijo.2017.141
Link: http://search.proquest.com/docview/1945729778/?pq-origsite=primo
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title: Lipid changes 8 years post gastric bypass in adolescents with severe obesity (FABS-5+ study)
format: Article
creator:
  • Shah, A
  • Jenkins, T
  • Gao, Z
  • Daniels, S
  • Urbina, E
  • Kirk, S
  • Siegel, R
  • Inge, T
subjects:
  • Cholesterol
  • Adolescents
  • Medical Research
  • Body Mass Index
  • Obesity
  • Youth
  • Cholesterol
  • Cholesterol
  • Lipids
  • Body Mass Index
  • Surgery
  • Risk Analysis
  • Lipids
  • Body Mass
  • Gastrointestinal Surgery
  • Weight Control
  • Lipoproteins (High Density)
  • Surgery
  • Body Mass
  • Cardiovascular Diseases
ispartof: International Journal of Obesity, Oct 2017, Vol.41(10), pp.1579-1584
description: Objective:Severe obesity in adolescents is increasing and few effective treatments exist. Bariatric surgery is one option, but the extent to which surgery influences cardiovascular risk factors over time in youth is not clear. We hypothesized that Roux-en Y gastric bypass (RYGB) would be associated with sustained improvements in lipids over time (>5 years).Participants/Methods:Youth who underwent RYGB from 2001 to 2007 were recruited for the Follow-up of Adolescent Bariatric Surgery-5+ (FABS-5+) in 2011-2014. Baseline body mass index (BMI) and lipids were abstracted from medical records. Follow-up data were obtained at a research visit. Analyses included paired t-tests to assess changes in BMI and lipids over time. General linear models were used to evaluate predictors of high-density lipoprotein (HDL) and non-HDL-cholesterol at follow-up. A non-operative group was recruited for comparison.Results:Surgical participants (n=58) were a mean±s.d. age of 17±2 years at baseline and 25±2 years...
language: eng
source:
identifier: ISSN: 03070565 ; E-ISSN: 14765497 ; DOI: 10.1038/ijo.2017.141
fulltext: fulltext
issn:
  • 03070565
  • 0307-0565
  • 14765497
  • 1476-5497
url: Link


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titleLipid changes 8 years post gastric bypass in adolescents with severe obesity (FABS-5+ study)
creatorShah, A ; Jenkins, T ; Gao, Z ; Daniels, S ; Urbina, E ; Kirk, S ; Siegel, R ; Inge, T
ispartofInternational Journal of Obesity, Oct 2017, Vol.41(10), pp.1579-1584
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subjectCholesterol ; Adolescents ; Medical Research ; Body Mass Index ; Obesity ; Youth ; Cholesterol ; Cholesterol ; Lipids ; Body Mass Index ; Surgery ; Risk Analysis ; Lipids ; Body Mass ; Gastrointestinal Surgery ; Weight Control ; Lipoproteins (High Density) ; Surgery ; Body Mass ; Cardiovascular Diseases
descriptionObjective:Severe obesity in adolescents is increasing and few effective treatments exist. Bariatric surgery is one option, but the extent to which surgery influences cardiovascular risk factors over time in youth is not clear. We hypothesized that Roux-en Y gastric bypass (RYGB) would be associated with sustained improvements in lipids over time (>5 years).Participants/Methods:Youth who underwent RYGB from 2001 to 2007 were recruited for the Follow-up of Adolescent Bariatric Surgery-5+ (FABS-5+) in 2011-2014. Baseline body mass index (BMI) and lipids were abstracted from medical records. Follow-up data were obtained at a research visit. Analyses included paired t-tests to assess changes in BMI and lipids over time. General linear models were used to evaluate predictors of high-density lipoprotein (HDL) and non-HDL-cholesterol at follow-up. A non-operative group was recruited for comparison.Results:Surgical participants (n=58) were a mean±s.d. age of 17±2 years at baseline and 25±2 years...
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titleLipid changes 8 years post gastric bypass in adolescents with severe obesity (FABS-5+ study)
descriptionObjective:Severe obesity in adolescents is increasing and few effective treatments exist. Bariatric surgery is one option, but the extent to which surgery influences cardiovascular risk factors over time in youth is not clear. We hypothesized that Roux-en Y gastric bypass (RYGB) would be associated with sustained improvements in lipids over time (>5 years).Participants/Methods:Youth who underwent RYGB from 2001 to 2007 were recruited for the Follow-up of Adolescent Bariatric Surgery-5+ (FABS-5+) in 2011-2014. Baseline body mass index (BMI) and lipids were abstracted from medical records. Follow-up data were obtained at a research visit. Analyses included paired t-tests to assess changes in BMI and lipids over time. General linear models were used to evaluate predictors of high-density lipoprotein (HDL) and non-HDL-cholesterol at follow-up. A non-operative group was recruited for comparison.Results:Surgical participants (n=58) were a mean±s.d. age of 17±2 years at baseline and 25±2 years...
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abstractObjective:Severe obesity in adolescents is increasing and few effective treatments exist. Bariatric surgery is one option, but the extent to which surgery influences cardiovascular risk factors over time in youth is not clear. We hypothesized that Roux-en Y gastric bypass (RYGB) would be associated with sustained improvements in lipids over time (>5 years).Participants/Methods:Youth who underwent RYGB from 2001 to 2007 were recruited for the Follow-up of Adolescent Bariatric Surgery-5+ (FABS-5+) in 2011-2014. Baseline body mass index (BMI) and lipids were abstracted from medical records. Follow-up data were obtained at a research visit. Analyses included paired t-tests to assess changes in BMI and lipids over time. General linear models were used to evaluate predictors of high-density lipoprotein (HDL) and non-HDL-cholesterol at follow-up. A non-operative group was recruited for comparison.Results:Surgical participants (n=58) were a mean±s.d. age of 17±2 years at baseline and 25±2 years...
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pubNature Publishing Group
doi10.1038/ijo.2017.141
urlhttp://search.proquest.com/docview/1945729778/
date2017-10-01