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Prospective Validation of a Biomarker-Based Rule Out Strategy for Functionally Relevant Coronary Artery Disease.

BACKGROUNDThis study aimed to prospectively advance a rule-out strategy for functionally significant coronary artery disease (CAD) by use of high-sensitivity cardiac troponin I (hs-cTnI) from bench to bedside, by application of a 3-step approach: validation in serum, correlation in plasma, and appli... Full description

Journal Title: Clinical chemistry February 2018, Vol.64(2), pp.386-395
Main Author: Walter, Joan E
Other Authors: Honegger, Ursina , Puelacher, Christian , Mueller, Deborah , Wagener, Max , Schaerli, Nicolas , Strebel, Ivo , Twerenbold, Raphael , Boeddinghaus, Jasper , Nestelberger, Thomas , Sazgary, Lorraine , Marbot, Stella , Du Fay de Lavallaz, Jeanne , Kaiser, Christoph , Osswald, Stefan , Wild, Damian , Rentsch, Katharina , Zellweger, Michael , Reichlin, Tobias , Mueller, Christian
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1530-8561 ; DOI: 10.1373/clinchem.2017.277210
Link: http://search.proquest.com/docview/1952108972/?pq-origsite=primo
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title: Prospective Validation of a Biomarker-Based Rule Out Strategy for Functionally Relevant Coronary Artery Disease.
format: Article
creator:
  • Walter, Joan E
  • Honegger, Ursina
  • Puelacher, Christian
  • Mueller, Deborah
  • Wagener, Max
  • Schaerli, Nicolas
  • Strebel, Ivo
  • Twerenbold, Raphael
  • Boeddinghaus, Jasper
  • Nestelberger, Thomas
  • Sazgary, Lorraine
  • Marbot, Stella
  • Du Fay de Lavallaz, Jeanne
  • Kaiser, Christoph
  • Osswald, Stefan
  • Wild, Damian
  • Rentsch, Katharina
  • Zellweger, Michael
  • Reichlin, Tobias
  • Mueller, Christian
subjects:
  • Aged–Blood
  • Biomarkers–Blood
  • Coronary Artery Disease–Diagnosis
  • Exercise Test–Diagnostic Imaging
  • Female–Blood
  • Humans–Blood
  • Male–Blood
  • Middle Aged–Blood
  • Multimodal Imaging–Blood
  • Prognosis–Blood
  • Prospective Studies–Blood
  • Sensitivity and Specificity–Blood
  • Tomography, Emission-Computed, Single-Photon–Blood
  • Tomography, X-Ray Computed–Blood
  • Troponin I–Blood
  • Biomarkers
  • Troponin I
ispartof: Clinical chemistry, February 2018, Vol.64(2), pp.386-395
description: BACKGROUNDThis study aimed to prospectively advance a rule-out strategy for functionally significant coronary artery disease (CAD) by use of high-sensitivity cardiac troponin I (hs-cTnI) from bench to bedside, by application of a 3-step approach: validation in serum, correlation in plasma, and application...
language: eng
source:
identifier: E-ISSN: 1530-8561 ; DOI: 10.1373/clinchem.2017.277210
fulltext: fulltext
issn:
  • 15308561
  • 1530-8561
url: Link


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titleProspective Validation of a Biomarker-Based Rule Out Strategy for Functionally Relevant Coronary Artery Disease.
creatorWalter, Joan E ; Honegger, Ursina ; Puelacher, Christian ; Mueller, Deborah ; Wagener, Max ; Schaerli, Nicolas ; Strebel, Ivo ; Twerenbold, Raphael ; Boeddinghaus, Jasper ; Nestelberger, Thomas ; Sazgary, Lorraine ; Marbot, Stella ; Du Fay de Lavallaz, Jeanne ; Kaiser, Christoph ; Osswald, Stefan ; Wild, Damian ; Rentsch, Katharina ; Zellweger, Michael ; Reichlin, Tobias ; Mueller, Christian
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ispartofClinical chemistry, February 2018, Vol.64(2), pp.386-395
identifierE-ISSN: 1530-8561 ; DOI: 10.1373/clinchem.2017.277210
subjectAged–Blood ; Biomarkers–Blood ; Coronary Artery Disease–Diagnosis ; Exercise Test–Diagnostic Imaging ; Female–Blood ; Humans–Blood ; Male–Blood ; Middle Aged–Blood ; Multimodal Imaging–Blood ; Prognosis–Blood ; Prospective Studies–Blood ; Sensitivity and Specificity–Blood ; Tomography, Emission-Computed, Single-Photon–Blood ; Tomography, X-Ray Computed–Blood ; Troponin I–Blood ; Biomarkers ; Troponin I
descriptionBACKGROUNDThis study aimed to prospectively advance a rule-out strategy for functionally significant coronary artery disease (CAD) by use of high-sensitivity cardiac troponin I (hs-cTnI) from bench to bedside, by application of a 3-step approach: validation in serum, correlation in plasma, and application...
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abstractBACKGROUNDThis study aimed to prospectively advance a rule-out strategy for functionally significant coronary artery disease (CAD) by use of high-sensitivity cardiac troponin I (hs-cTnI) from bench to bedside, by application of a 3-step approach: validation in serum, correlation in plasma, and application...
doi10.1373/clinchem.2017.277210
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issn00099147
date2018-02-01