schliessen

Filtern

 

Bibliotheken

Anti-inflammatory effect of Allium hookeri on carrageenan-induced air pouch mouse model.

Inflammation is a commonly observed immune reaction, and rheumatoid arthritis is a particularly severe inflammatory disease. In this study, we used an air pouch mouse model to evaluate the anti-inflammatory potential of Allium hookeri, which has both been used as a culinary material and a traditiona... Full description

Journal Title: PloS one 2017, Vol.12(12), p.e0190305
Main Author: Kim, Jung-Eun
Other Authors: Park, Kyung-Mok , Lee, Soon-Young , Seo, Ji-Hye , Yoon, In-Soo , Bae, Chun-Sik , Yoo, Jin-Cheol , Bang, Mi-Ae , Cho, Seung-Sik , Park, Dae-Hun
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1932-6203 ; DOI: 1932-6203 ; DOI: 10.1371/journal.pone.0190305
Link: http://search.proquest.com/docview/1981766530/?pq-origsite=primo
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: proquest1981766530
title: Anti-inflammatory effect of Allium hookeri on carrageenan-induced air pouch mouse model.
format: Article
creator:
  • Kim, Jung-Eun
  • Park, Kyung-Mok
  • Lee, Soon-Young
  • Seo, Ji-Hye
  • Yoon, In-Soo
  • Bae, Chun-Sik
  • Yoo, Jin-Cheol
  • Bang, Mi-Ae
  • Cho, Seung-Sik
  • Park, Dae-Hun
subjects:
  • Allium–Metabolism
  • Animals–Toxicity
  • Carrageenan–Metabolism
  • Cytokines–Chemically Induced
  • Inflammation–Metabolism
  • Inflammation Mediators–Prevention & Control
  • Mice–Metabolism
  • Cytokines
  • Inflammation Mediators
  • Carrageenan
ispartof: PloS one, 2017, Vol.12(12), p.e0190305
description: Inflammation is a commonly observed immune reaction, and rheumatoid arthritis is a particularly severe inflammatory disease. In this study, we used an air pouch mouse model to evaluate the anti-inflammatory potential of Allium hookeri, which has both been used as a culinary material and a traditional medicine in south-eastern Asia for many years. Allium hookeri suppressed typical symptoms of inflammation, such as condensation of the air pouch membrane, and inhibited the expression of several inducible proinflammatory cytokines such as IL-1[beta], IL-6, IL-13, and TNF-[alpha]. In order to determine the molecules modulating the inflammatory effect of carrageenan treatment, the components in Allium hookeri were analyzed by GC-MS, and linoleic acid, which have anti-inflammatory effect, was detected. From the results, we concluded that the anti-inflammatory effect of Allium hookeri might be attributed to linoleic acid, which could be promising candidates for anti-inflammatory drugs that have no adverse effects.
language: eng
source:
identifier: E-ISSN: 1932-6203 ; DOI: 1932-6203 ; DOI: 10.1371/journal.pone.0190305
fulltext: fulltext
issn:
  • 19326203
  • 1932-6203
url: Link


@attributes
ID887806096
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid1981766530
sourceidproquest
recordidTN_proquest1981766530
sourcesystemOther
pqid1981766530
galeid520531080
display
typearticle
titleAnti-inflammatory effect of Allium hookeri on carrageenan-induced air pouch mouse model.
creatorKim, Jung-Eun ; Park, Kyung-Mok ; Lee, Soon-Young ; Seo, Ji-Hye ; Yoon, In-Soo ; Bae, Chun-Sik ; Yoo, Jin-Cheol ; Bang, Mi-Ae ; Cho, Seung-Sik ; Park, Dae-Hun
contributorKim, Jung-Eun (correspondence author) ; Kim, Jung-Eun (record owner)
ispartofPloS one, 2017, Vol.12(12), p.e0190305
identifier
subjectAllium–Metabolism ; Animals–Toxicity ; Carrageenan–Metabolism ; Cytokines–Chemically Induced ; Inflammation–Metabolism ; Inflammation Mediators–Prevention & Control ; Mice–Metabolism ; Cytokines ; Inflammation Mediators ; Carrageenan
languageeng
source
descriptionInflammation is a commonly observed immune reaction, and rheumatoid arthritis is a particularly severe inflammatory disease. In this study, we used an air pouch mouse model to evaluate the anti-inflammatory potential of Allium hookeri, which has both been used as a culinary material and a traditional medicine in south-eastern Asia for many years. Allium hookeri suppressed typical symptoms of inflammation, such as condensation of the air pouch membrane, and inhibited the expression of several inducible proinflammatory cytokines such as IL-1[beta], IL-6, IL-13, and TNF-[alpha]. In order to determine the molecules modulating the inflammatory effect of carrageenan treatment, the components in Allium hookeri were analyzed by GC-MS, and linoleic acid, which have anti-inflammatory effect, was detected. From the results, we concluded that the anti-inflammatory effect of Allium hookeri might be attributed to linoleic acid, which could be promising candidates for anti-inflammatory drugs that have no adverse effects.
version7
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
backlink$$Uhttp://search.proquest.com/docview/1981766530/?pq-origsite=primo$$EView_record_in_ProQuest_(subscribers_only)
search
creatorcontrib
0Kim, Jung-Eun
1Park, Kyung-Mok
2Lee, Soon-Young
3Seo, Ji-Hye
4Yoon, In-Soo
5Bae, Chun-Sik
6Yoo, Jin-Cheol
7Bang, Mi-Ae
8Cho, Seung-Sik
9Park, Dae-Hun
titleAnti-inflammatory effect of Allium hookeri on carrageenan-induced air pouch mouse model.
subject
0Allium–Metabolism
1Animals–Toxicity
2Carrageenan–Metabolism
3Cytokines–Chemically Induced
4Inflammation–Metabolism
5Inflammation Mediators–Prevention & Control
6Mice–Metabolism
7Cytokines
8Inflammation Mediators
9Carrageenan
general
0English
11932-6203
210.1371/journal.pone.0190305
3MEDLINE (ProQuest)
4ProQuest Biological Science Collection
5ProQuest Natural Science Collection
6ProQuest SciTech Collection
7Biological Science Database
8Natural Science Collection
9SciTech Premium Collection
10Health Research Premium Collection
11Health Research Premium Collection (Alumni edition)
sourceidproquest
recordidproquest1981766530
issn
019326203
11932-6203
rsrctypearticle
creationdate2017
addtitlePloS one
searchscope
01007527
11007944
210000004
310000038
410000050
510000120
610000159
710000238
810000253
910000260
1010000270
1110000271
1210000302
13proquest
scope
01007527
11007944
210000004
310000038
410000050
510000120
610000159
710000238
810000253
910000260
1010000270
1110000271
1210000302
13proquest
lsr43
01007527false
11007944false
210000004false
310000038false
410000050false
510000120false
610000159false
710000238false
810000253false
910000260false
1010000270false
1110000271false
1210000302false
contributorKim, Jung-Eun
startdate20170101
enddate20170101
citationpf e0190305 pt e0190305 vol 12 issue 12
lsr30VSR-Enriched:[description, galeid, pqid]
sort
titleAnti-inflammatory effect of Allium hookeri on carrageenan-induced air pouch mouse model.
authorKim, Jung-Eun ; Park, Kyung-Mok ; Lee, Soon-Young ; Seo, Ji-Hye ; Yoon, In-Soo ; Bae, Chun-Sik ; Yoo, Jin-Cheol ; Bang, Mi-Ae ; Cho, Seung-Sik ; Park, Dae-Hun
creationdate20170101
lso0120170101
facets
frbrgroupid5122076296918500063
frbrtype5
newrecords20181218
languageeng
creationdate2017
topic
0Allium–Metabolism
1Animals–Toxicity
2Carrageenan–Metabolism
3Cytokines–Chemically Induced
4Inflammation–Metabolism
5Inflammation Mediators–Prevention & Control
6Mice–Metabolism
7Cytokines
8Inflammation Mediators
9Carrageenan
collection
0MEDLINE (ProQuest)
1ProQuest Biological Science Collection
2ProQuest Natural Science Collection
3ProQuest SciTech Collection
4Biological Science Database
5Natural Science Collection
6SciTech Premium Collection
7Health Research Premium Collection
8Health Research Premium Collection (Alumni edition)
prefilterarticles
rsrctypearticles
creatorcontrib
0Kim, Jung-Eun
1Park, Kyung-Mok
2Lee, Soon-Young
3Seo, Ji-Hye
4Yoon, In-Soo
5Bae, Chun-Sik
6Yoo, Jin-Cheol
7Bang, Mi-Ae
8Cho, Seung-Sik
9Park, Dae-Hun
jtitlePloS one
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Kim
1Park
2Lee
3Seo
4Yoon
5Bae
6Yoo
7Bang
8Cho
aufirst
0Jung-Eun
1Kyung-Mok
2Soon-Young
3Ji-Hye
4In-Soo
5Chun-Sik
6Jin-Cheol
7Mi-Ae
8Seung-Sik
9Dae-Hun
au
0Kim, Jung-Eun
1Park, Kyung-Mok
2Lee, Soon-Young
3Seo, Ji-Hye
4Yoon, In-Soo
5Bae, Chun-Sik
6Yoo, Jin-Cheol
7Bang, Mi-Ae
8Cho, Seung-Sik
9Park, Dae-Hun
addauKim, Jung-Eun
atitleAnti-inflammatory effect of Allium hookeri on carrageenan-induced air pouch mouse model.
jtitlePloS one
risdate20170101
volume12
issue12
spagee0190305
epagee0190305
pagese0190305
eissn1932-6203
formatjournal
genrearticle
ristypeJOUR
doi10.1371/journal.pone.0190305
urlhttp://search.proquest.com/docview/1981766530/
date2017-01-01