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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

Body fat distribution is a heritable risk factor for a range of adverse health consequences, including hyperlipidemia and type 2 diabetes. To identify protein-coding variants associated with body fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, we analyzed 228,985 predi... Full description

Journal Title: BioRxiv Jun 30, 2018
Main Author: Justice, Anne
Other Authors: Karaderi, Tugce , Highland, Heather , Young, Kristin , Graff, Mariaelisa , Lu, Yingchang , Auer, Paul , Fine, Rebecca , Guo, Xiuqing , Schurmann, Claudia , Lempradl, Adelheid , Marouli, Eirini , Mahajan, Anubha , Winkler, Thomas , Locke, Adam , Medina-Gomez, Carolina , Vedantam, Sailaja , Giri, Ayush , Mudgal, Poorva , Ng, Maggie , Heard-Costa, Nancy , Feitosa, Mary , Manning, Alisa , Willems, Sara , Sivapalaratnam, Suthesh , Abecasis, Goncalo , Alam, Dewan , Allison, Matthew , Amouyel, Philippe , Arzumanyan, Zorayr , Balkau, Beverley , Bastarache, Lisa , Bergmann, Sven , Bielak, Lawrence , Boehnke, Michael , Boeing, Heiner , Boerwinkle, Eric , Bork-Jensen, Jette , Bottinger, Erwin , Bowden, Donald , Brandslund, Ivan , Broer, Linda , Burt, Amber , Butterworth, Adam , Caulfield, Mark , Cesana, Giancarlo , Chambers, John , Chasman, Daniel , Chen, Yii-Der , Chowdhury, Rajiv , Chu, Audrey , Collins, Francis , Cook, James , Cox, Amanda , Crosslin, David , Danesh, John , Dedoussis, George , Demerath, Ellen , Dennis, Joe , Denny, Josh , Drenos, Fotios , Dunning, Alison , Easton, Douglas , Elliott, Paul , Evangelou, Evangelos , Feng, Shuang , Ferrannini, Ele , Ferrieres, Jean , Florez, Jose , Fornage, Myriam , Fox, Caroline , Franks, Paul , Friedrich, Nele , Gan, Wei , Gandin, Ilaria , Gasparini, Paolo , Giedraitis, Vilmantas , Girotto, Giorgia , Gorski, Mathias , Grallert, Harald , Grarup, Niels , Grove, Megan , Gustafsson, Stefan , Haessler, Jeff , Hansen, Torben , Hattersley, Andrew , Hayward, Caroline , Heid, Iris , Holmen, Oddgeir , Howson, Joanna , Hu, Yao , Yi-Jen, Hung , Hveem, Kristian , Ikram, M , Ingelsson, Erik , Jackson, Anne , Jarvik, Gail , Jia, Yucheng , Jousilahti, Pekka , Justesen, Johanne , Kahali, Bratati , Karaleftheri, Maria , Kardia, Sharon , Karpe, Fredrik , Kee, Frank , Kitajima, Hidetoshi , Komulainen, Pirjo , Kooner, Jaspal , Kovacs, Peter , Kuulasmaa, Kari , Kuusisto, Johanna , Laakso, Markku , Lakka, Timo , Lamparter, David , Lange, Leslie , Langenberg, Claudia , Larson, Eric , Lee, Nanette , Wen-Jane, Lee , Lewis, Cora , Li, Huaixing , Li, Jin , Li-Gao, Ruifang , Li-An, Lin , Xu, Lin , Lind, Lars , Linneberg, Allan , Liu, Ching-Ti , Liu, Dajiang , Luan, Jianan , Macgregor, Stuart , Marten, Jonathan , Masca, Nicholas , Mccarthy, Mark , Meidtner, Karina , Mihailov, Evelin , Moilanen, Leena , Moitry, Marie , Mook-Kanamori, Dennis , Morgan, Anna , Morris, Andrew , Munroe, Patricia , Narisu, Narisu , Nelson, Christopher , Neville, Matt , Ntalla, Ioanna , Oconnel, Jeffrey , Owen, Katharine , Pedersen, Oluf , Peloso, Gina , Pennell, Craig , Perola, Markus , Perry, James , Perry, John , Pers, Tune , Pirie, Ailith , Polasek, Ozren , Raitakari, Olli , Rasheed, Asif , Raulerson, Chelsea , Rauramaa, Rainer , Reilly, Dermot , Reiner, Alex , Ridker, Paul , Rivas, Manuel , Robertson, Neil , Robino, Antonietta , Rudan, Igor , Ruth, Katherine , Saleheen, Danish , Salomaa, Veikko , Samani, Nilesh , Schreiner, Pamela , Schulze, Matthias , Scott, Robert , Segura-Lepe, Marcelo , Sim, Xueling , Slater, Andrew , Small, Kerrin , Smith, Blair , Smith, Jennifer , Southam, Lorraine , Spector, Timothy , Speliotes, Elizabeth , Stefansson, Kari , Steinthorsdottir, Valgerdur , Stirrups, Kathleen , Strauch, Konstantin , Stringham, Heather , Stumvoll, Michael , Sun, Liang , Surendran, Praveen , Tardif, Jean-Claude , Taylor, Kent , Teumer, Alexander , Thompson, Deborah , Thorleifsson, Gudmar , Thorsteinsdottir, Unnur , Thuesen, Betina , Torres, Mina , Tsafantakis, Emmanouil , Tuomilehto, Jaakko , Uusitupa, Matti , Van Duijn, Cornelia , Vanhala, Mauno , Varma, Rohit , Vermeulen, Sita , Vestergaard, Henrik , Vitart, Veronique , Vogt, Thomas , Vuckovic, Dragana , Wagenknecht, Lynne , Walker, Mark , Wallentin, Lars , Wang, Feijie , Wang, Carol , Wang, Shuai , Wareham, Nicholas , Warren, Helen , Waterworth, Dawn , Wessel, Jennifer , White, Harvey , Willer, Cristen , Wilson, James , Wood, Andrew , Wu, Ying , Yaghootkar, Hanieh , Yao, Jie , Yerges-Armstrong, Laura , Young, Robin , Zeggini, Eleftheria , Zhan, Xiaowei , Zhang, Weihua , Zhao, Jing , Zhao, Wei , He, Zheng , Zhou, Wei , Zillikens, M , Consortium, Epic-Cvd , Consortium, Exomebp , Consortium, Reprogen , Rivadeneira, Fernando , Borecki, Ingrid , Pospisilik, John , Deloukas, Panos , Frayling, Timothy , Lettre, Guillaume , Mohlke, Karen , Rotter, Jerome , Kutalik, Zoltan
Format: Electronic Article Electronic Article
Language: English
Subjects:
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Quelle: © ProQuest LLC All rights reserved
ID: DOI: 10.1101/352674
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title: PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION
format: Article
creator:
  • Justice, Anne
  • Karaderi, Tugce
  • Highland, Heather
  • Young, Kristin
  • Graff, Mariaelisa
  • Lu, Yingchang
  • Auer, Paul
  • Fine, Rebecca
  • Guo, Xiuqing
  • Schurmann, Claudia
  • Lempradl, Adelheid
  • Marouli, Eirini
  • Mahajan, Anubha
  • Winkler, Thomas
  • Locke, Adam
  • Medina-Gomez, Carolina
  • Vedantam, Sailaja
  • Giri, Ayush
  • Mudgal, Poorva
  • Ng, Maggie
  • Heard-Costa, Nancy
  • Feitosa, Mary
  • Manning, Alisa
  • Willems, Sara
  • Sivapalaratnam, Suthesh
  • Abecasis, Goncalo
  • Alam, Dewan
  • Allison, Matthew
  • Amouyel, Philippe
  • Arzumanyan, Zorayr
  • Balkau, Beverley
  • Bastarache, Lisa
  • Bergmann, Sven
  • Bielak, Lawrence
  • Boehnke, Michael
  • Boeing, Heiner
  • Boerwinkle, Eric
  • Bork-Jensen, Jette
  • Bottinger, Erwin
  • Bowden, Donald
  • Brandslund, Ivan
  • Broer, Linda
  • Burt, Amber
  • Butterworth, Adam
  • Caulfield, Mark
  • Cesana, Giancarlo
  • Chambers, John
  • Chasman, Daniel
  • Chen, Yii-Der
  • Chowdhury, Rajiv
  • Chu, Audrey
  • Collins, Francis
  • Cook, James
  • Cox, Amanda
  • Crosslin, David
  • Danesh, John
  • Dedoussis, George
  • Demerath, Ellen
  • Dennis, Joe
  • Denny, Josh
  • Drenos, Fotios
  • Dunning, Alison
  • Easton, Douglas
  • Elliott, Paul
  • Evangelou, Evangelos
  • Feng, Shuang
  • Ferrannini, Ele
  • Ferrieres, Jean
  • Florez, Jose
  • Fornage, Myriam
  • Fox, Caroline
  • Franks, Paul
  • Friedrich, Nele
  • Gan, Wei
  • Gandin, Ilaria
  • Gasparini, Paolo
  • Giedraitis, Vilmantas
  • Girotto, Giorgia
  • Gorski, Mathias
  • Grallert, Harald
  • Grarup, Niels
  • Grove, Megan
  • Gustafsson, Stefan
  • Haessler, Jeff
  • Hansen, Torben
  • Hattersley, Andrew
  • Hayward, Caroline
  • Heid, Iris
  • Holmen, Oddgeir
  • Howson, Joanna
  • Hu, Yao
  • Yi-Jen, Hung
  • Hveem, Kristian
  • Ikram, M
  • Ingelsson, Erik
  • Jackson, Anne
  • Jarvik, Gail
  • Jia, Yucheng
  • Jousilahti, Pekka
  • Justesen, Johanne
  • Kahali, Bratati
  • Karaleftheri, Maria
  • Kardia, Sharon
  • Karpe, Fredrik
  • Kee, Frank
  • Kitajima, Hidetoshi
  • Komulainen, Pirjo
  • Kooner, Jaspal
  • Kovacs, Peter
  • Kuulasmaa, Kari
  • Kuusisto, Johanna
  • Laakso, Markku
  • Lakka, Timo
  • Lamparter, David
  • Lange, Leslie
  • Langenberg, Claudia
  • Larson, Eric
  • Lee, Nanette
  • Wen-Jane, Lee
  • Lewis, Cora
  • Li, Huaixing
  • Li, Jin
  • Li-Gao, Ruifang
  • Li-An, Lin
  • Xu, Lin
  • Lind, Lars
  • Linneberg, Allan
  • Liu, Ching-Ti
  • Liu, Dajiang
  • Luan, Jianan
  • Macgregor, Stuart
  • Marten, Jonathan
  • Masca, Nicholas
  • Mccarthy, Mark
  • Meidtner, Karina
  • Mihailov, Evelin
  • Moilanen, Leena
  • Moitry, Marie
  • Mook-Kanamori, Dennis
  • Morgan, Anna
  • Morris, Andrew
  • Munroe, Patricia
  • Narisu, Narisu
  • Nelson, Christopher
  • Neville, Matt
  • Ntalla, Ioanna
  • Oconnel, Jeffrey
  • Owen, Katharine
  • Pedersen, Oluf
  • Peloso, Gina
  • Pennell, Craig
  • Perola, Markus
  • Perry, James
  • Perry, John
  • Pers, Tune
  • Pirie, Ailith
  • Polasek, Ozren
  • Raitakari, Olli
  • Rasheed, Asif
  • Raulerson, Chelsea
  • Rauramaa, Rainer
  • Reilly, Dermot
  • Reiner, Alex
  • Ridker, Paul
  • Rivas, Manuel
  • Robertson, Neil
  • Robino, Antonietta
  • Rudan, Igor
  • Ruth, Katherine
  • Saleheen, Danish
  • Salomaa, Veikko
  • Samani, Nilesh
  • Schreiner, Pamela
  • Schulze, Matthias
  • Scott, Robert
  • Segura-Lepe, Marcelo
  • Sim, Xueling
  • Slater, Andrew
  • Small, Kerrin
  • Smith, Blair
  • Smith, Jennifer
  • Southam, Lorraine
  • Spector, Timothy
  • Speliotes, Elizabeth
  • Stefansson, Kari
  • Steinthorsdottir, Valgerdur
  • Stirrups, Kathleen
  • Strauch, Konstantin
  • Stringham, Heather
  • Stumvoll, Michael
  • Sun, Liang
  • Surendran, Praveen
  • Tardif, Jean-Claude
  • Taylor, Kent
  • Teumer, Alexander
  • Thompson, Deborah
  • Thorleifsson, Gudmar
  • Thorsteinsdottir, Unnur
  • Thuesen, Betina
  • Torres, Mina
  • Tsafantakis, Emmanouil
  • Tuomilehto, Jaakko
  • Uusitupa, Matti
  • Van Duijn, Cornelia
  • Vanhala, Mauno
  • Varma, Rohit
  • Vermeulen, Sita
  • Vestergaard, Henrik
  • Vitart, Veronique
  • Vogt, Thomas
  • Vuckovic, Dragana
  • Wagenknecht, Lynne
  • Walker, Mark
  • Wallentin, Lars
  • Wang, Feijie
  • Wang, Carol
  • Wang, Shuai
  • Wareham, Nicholas
  • Warren, Helen
  • Waterworth, Dawn
  • Wessel, Jennifer
  • White, Harvey
  • Willer, Cristen
  • Wilson, James
  • Wood, Andrew
  • Wu, Ying
  • Yaghootkar, Hanieh
  • Yao, Jie
  • Yerges-Armstrong, Laura
  • Young, Robin
  • Zeggini, Eleftheria
  • Zhan, Xiaowei
  • Zhang, Weihua
  • Zhao, Jing
  • Zhao, Wei
  • He, Zheng
  • Zhou, Wei
  • Zillikens, M
  • Consortium, Epic-Cvd
  • Consortium, Exomebp
  • Consortium, Reprogen
  • Rivadeneira, Fernando
  • Borecki, Ingrid
  • Pospisilik, John
  • Deloukas, Panos
  • Frayling, Timothy
  • Lettre, Guillaume
  • Mohlke, Karen
  • Rotter, Jerome
  • Kutalik, Zoltan
subjects:
  • Body Fat
  • Diabetes
  • Genes
  • Proteins
  • Lipids
  • Hip
  • Diabetes Mellitus (Non-Insulin Dependent)
  • RNA-Mediated Interference
  • Adiponectin
  • Genomes
  • Gene Frequency
  • Adipose Tissue
  • Risk Factors
  • Diabetes Mellitus
  • Homeostasis
  • Body Mass Index
  • Hyperlipidemia
  • Body Fat
ispartof: BioRxiv, Jun 30, 2018
description: Body fat distribution is a heritable risk factor for a range of adverse health consequences, including hyperlipidemia and type 2 diabetes. To identify protein-coding variants associated with body fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, we analyzed 228,985 predicted...
language: eng
source: © ProQuest LLC All rights reserved
identifier: DOI: 10.1101/352674
fulltext: fulltext_linktorsrc
url: Link


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titlePROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION
creatorJustice, Anne ; Karaderi, Tugce ; Highland, Heather ; Young, Kristin ; Graff, Mariaelisa ; Lu, Yingchang ; Auer, Paul ; Fine, Rebecca ; Guo, Xiuqing ; Schurmann, Claudia ; Lempradl, Adelheid ; Marouli, Eirini ; Mahajan, Anubha ; Winkler, Thomas ; Locke, Adam ; Medina-Gomez, Carolina ; Vedantam, Sailaja ; Giri, Ayush ; Mudgal, Poorva ; Ng, Maggie ; Heard-Costa, Nancy ; Feitosa, Mary ; Manning, Alisa ; Willems, Sara ; Sivapalaratnam, Suthesh ; Abecasis, Goncalo ; Alam, Dewan ; Allison, Matthew ; Amouyel, Philippe ; Arzumanyan, Zorayr ; Balkau, Beverley ; Bastarache, Lisa ; Bergmann, Sven ; Bielak, Lawrence ; Boehnke, Michael ; Boeing, Heiner ; Boerwinkle, Eric ; Bork-Jensen, Jette ; Bottinger, Erwin ; Bowden, Donald ; Brandslund, Ivan ; Broer, Linda ; Burt, Amber ; Butterworth, Adam ; Caulfield, Mark ; Cesana, Giancarlo ; Chambers, John ; Chasman, Daniel ; Chen, Yii-Der ; Chowdhury, Rajiv ; Chu, Audrey ; Collins, Francis ; Cook, James ; Cox, Amanda ; Crosslin, David ; Danesh, John ; Dedoussis, George ; Demerath, Ellen ; Dennis, Joe ; Denny, Josh ; Drenos, Fotios ; Dunning, Alison ; Easton, Douglas ; Elliott, Paul ; Evangelou, Evangelos ; Feng, Shuang ; Ferrannini, Ele ; Ferrieres, Jean ; Florez, Jose ; Fornage, Myriam ; Fox, Caroline ; Franks, Paul ; Friedrich, Nele ; Gan, Wei ; Gandin, Ilaria ; Gasparini, Paolo ; Giedraitis, Vilmantas ; Girotto, Giorgia ; Gorski, Mathias ; Grallert, Harald ; Grarup, Niels ; Grove, Megan ; Gustafsson, Stefan ; Haessler, Jeff ; Hansen, Torben ; Hattersley, Andrew ; Hayward, Caroline ; Heid, Iris ; Holmen, Oddgeir ; Howson, Joanna ; Hu, Yao ; Yi-Jen, Hung ; Hveem, Kristian ; Ikram, M ; Ingelsson, Erik ; Jackson, Anne ; Jarvik, Gail ; Jia, Yucheng ; Jousilahti, Pekka ; Justesen, Johanne ; Kahali, Bratati ; Karaleftheri, Maria ; Kardia, Sharon ; Karpe, Fredrik ; Kee, Frank ; Kitajima, Hidetoshi ; Komulainen, Pirjo ; Kooner, Jaspal ; Kovacs, Peter ; Kuulasmaa, Kari ; Kuusisto, Johanna ; Laakso, Markku ; Lakka, Timo ; Lamparter, David ; Lange, Leslie ; Langenberg, Claudia ; Larson, Eric ; Lee, Nanette ; Wen-Jane, Lee ; Lewis, Cora ; Li, Huaixing ; Li, Jin ; Li-Gao, Ruifang ; Li-An, Lin ; Xu, Lin ; Lind, Lars ; Linneberg, Allan ; Liu, Ching-Ti ; Liu, Dajiang ; Luan, Jianan ; Macgregor, Stuart ; Marten, Jonathan ; Masca, Nicholas ; Mccarthy, Mark ; Meidtner, Karina ; Mihailov, Evelin ; Moilanen, Leena ; Moitry, Marie ; Mook-Kanamori, Dennis ; Morgan, Anna ; Morris, Andrew ; Munroe, Patricia ; Narisu, Narisu ; Nelson, Christopher ; Neville, Matt ; Ntalla, Ioanna ; Oconnel, Jeffrey ; Owen, Katharine ; Pedersen, Oluf ; Peloso, Gina ; Pennell, Craig ; Perola, Markus ; Perry, James ; Perry, John ; Pers, Tune ; Pirie, Ailith ; Polasek, Ozren ; Raitakari, Olli ; Rasheed, Asif ; Raulerson, Chelsea ; Rauramaa, Rainer ; Reilly, Dermot ; Reiner, Alex ; Ridker, Paul ; Rivas, Manuel ; Robertson, Neil ; Robino, Antonietta ; Rudan, Igor ; Ruth, Katherine ; Saleheen, Danish ; Salomaa, Veikko ; Samani, Nilesh ; Schreiner, Pamela ; Schulze, Matthias ; Scott, Robert ; Segura-Lepe, Marcelo ; Sim, Xueling ; Slater, Andrew ; Small, Kerrin ; Smith, Blair ; Smith, Jennifer ; Southam, Lorraine ; Spector, Timothy ; Speliotes, Elizabeth ; Stefansson, Kari ; Steinthorsdottir, Valgerdur ; Stirrups, Kathleen ; Strauch, Konstantin ; Stringham, Heather ; Stumvoll, Michael ; Sun, Liang ; Surendran, Praveen ; Tardif, Jean-Claude ; Taylor, Kent ; Teumer, Alexander ; Thompson, Deborah ; Thorleifsson, Gudmar ; Thorsteinsdottir, Unnur ; Thuesen, Betina ; Torres, Mina ; Tsafantakis, Emmanouil ; Tuomilehto, Jaakko ; Uusitupa, Matti ; Van Duijn, Cornelia ; Vanhala, Mauno ; Varma, Rohit ; Vermeulen, Sita ; Vestergaard, Henrik ; Vitart, Veronique ; Vogt, Thomas ; Vuckovic, Dragana ; Wagenknecht, Lynne ; Walker, Mark ; Wallentin, Lars ; Wang, Feijie ; Wang, Carol ; Wang, Shuai ; Wareham, Nicholas ; Warren, Helen ; Waterworth, Dawn ; Wessel, Jennifer ; White, Harvey ; Willer, Cristen ; Wilson, James ; Wood, Andrew ; Wu, Ying ; Yaghootkar, Hanieh ; Yao, Jie ; Yerges-Armstrong, Laura ; Young, Robin ; Zeggini, Eleftheria ; Zhan, Xiaowei ; Zhang, Weihua ; Zhao, Jing ; Zhao, Wei ; He, Zheng ; Zhou, Wei ; Zillikens, M ; Consortium, Epic-Cvd ; Consortium, Exomebp ; Consortium, Reprogen ; Rivadeneira, Fernando ; Borecki, Ingrid ; Pospisilik, John ; Deloukas, Panos ; Frayling, Timothy ; Lettre, Guillaume ; Mohlke, Karen ; Rotter, Jerome ; Kutalik, Zoltan
ispartofBioRxiv, Jun 30, 2018
identifierDOI: 10.1101/352674
subjectBody Fat ; Diabetes ; Genes ; Proteins ; Lipids ; Hip ; Diabetes Mellitus (Non-Insulin Dependent) ; RNA-Mediated Interference ; Adiponectin ; Genomes ; Gene Frequency ; Adipose Tissue ; Risk Factors ; Diabetes Mellitus ; Homeostasis ; Body Mass Index ; Hyperlipidemia ; Body Fat
descriptionBody fat distribution is a heritable risk factor for a range of adverse health consequences, including hyperlipidemia and type 2 diabetes. To identify protein-coding variants associated with body fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, we analyzed 228,985 predicted...
languageeng
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2Highland, Heather
3Young, Kristin
4Graff, Mariaelisa
5Lu, Yingchang
6Auer, Paul
7Fine, Rebecca
8Guo, Xiuqing
9Schurmann, Claudia
10Lempradl, Adelheid
11Marouli, Eirini
12Mahajan, Anubha
13Winkler, Thomas
14Locke, Adam
15Medina-Gomez, Carolina
16Vedantam, Sailaja
17Giri, Ayush
18Mudgal, Poorva
19Ng, Maggie
20Heard-Costa, Nancy
21Feitosa, Mary
22Manning, Alisa
23Willems, Sara
24Sivapalaratnam, Suthesh
25Abecasis, Goncalo
26Alam, Dewan
27Allison, Matthew
28Amouyel, Philippe
29Arzumanyan, Zorayr
30Balkau, Beverley
31Bastarache, Lisa
32Bergmann, Sven
33Bielak, Lawrence
34Boehnke, Michael
35Boeing, Heiner
36Boerwinkle, Eric
37Bork-Jensen, Jette
38Bottinger, Erwin
39Bowden, Donald
40Brandslund, Ivan
41Broer, Linda
42Burt, Amber
43Butterworth, Adam
44Caulfield, Mark
45Cesana, Giancarlo
46Chambers, John
47Chasman, Daniel
48Chen, Yii-Der
49Chowdhury, Rajiv
50Chu, Audrey
51Collins, Francis
52Cook, James
53Cox, Amanda
54Crosslin, David
55Danesh, John
56Dedoussis, George
57Demerath, Ellen
58Dennis, Joe
59Denny, Josh
60Drenos, Fotios
61Dunning, Alison
62Easton, Douglas
63Elliott, Paul
64Evangelou, Evangelos
65Feng, Shuang
66Ferrannini, Ele
67Ferrieres, Jean
68Florez, Jose
69Fornage, Myriam
70Fox, Caroline
71Franks, Paul
72Friedrich, Nele
73Gan, Wei
74Gandin, Ilaria
75Gasparini, Paolo
76Giedraitis, Vilmantas
77Girotto, Giorgia
78Gorski, Mathias
79Grallert, Harald
80Grarup, Niels
81Grove, Megan
82Gustafsson, Stefan
83Haessler, Jeff
84Hansen, Torben
85Hattersley, Andrew
86Hayward, Caroline
87Heid, Iris
88Holmen, Oddgeir
89Howson, Joanna
90Hu, Yao
91Yi-Jen, Hung
92Hveem, Kristian
93Ikram, M
94Ingelsson, Erik
95Jackson, Anne
96Jarvik, Gail
97Jia, Yucheng
98Jousilahti, Pekka
99Justesen, Johanne
100...
titlePROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION
descriptionBody fat distribution is a heritable risk factor for a range of adverse health consequences, including hyperlipidemia and type 2 diabetes. To identify protein-coding variants associated with body fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, we analyzed 228,985 predicted...
subject
0Body Fat
1Diabetes
2Genes
3Proteins
4Lipids
5Hip
6Diabetes Mellitus (Non-Insulin Dependent)
7RNA-Mediated Interference
8Adiponectin
9Genomes
10Gene Frequency
11Adipose Tissue
12Risk Factors
13Diabetes Mellitus
14Homeostasis
15Body Mass Index
16Hyperlipidemia
general
0English
1Cold Spring Harbor Laboratory Press
210.1101/352674
3Biological Science Database
4Publicly Available Content Database
5ProQuest Biological Science Collection
6ProQuest Natural Science Collection
7ProQuest SciTech Collection
8Natural Science Collection
9ProQuest Central (new)
10ProQuest Central K-12
11ProQuest Central Korea
12SciTech Premium Collection
13ProQuest Central Essentials
14ProQuest One Academic
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titlePROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION
authorJustice, Anne ; Karaderi, Tugce ; Highland, Heather ; Young, Kristin ; Graff, Mariaelisa ; Lu, Yingchang ; Auer, Paul ; Fine, Rebecca ; Guo, Xiuqing ; Schurmann, Claudia ; Lempradl, Adelheid ; Marouli, Eirini ; Mahajan, Anubha ; Winkler, Thomas ; Locke, Adam ; Medina-Gomez, Carolina ; Vedantam, Sailaja...
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lso0120180630
facets
frbrgroupid1641768658919574273
frbrtype6
newrecords20180917
languageeng
creationdate2018
topic
0Body Fat
1Diabetes
2Genes
3Proteins
4Lipids
5Hip
6Diabetes Mellitus (Non-Insulin Dependent)
7RNA-Mediated Interference
8Adiponectin
9Genomes
10Gene Frequency
11Adipose Tissue
12Risk Factors
13Diabetes Mellitus
14Homeostasis
15Body Mass Index
16Hyperlipidemia
collection
0Biological Science Database
1Publicly Available Content Database
2ProQuest Biological Science Collection
3ProQuest Natural Science Collection
4ProQuest SciTech Collection
5Natural Science Collection
6ProQuest Central (new)
7ProQuest Central K-12
8ProQuest Central Korea
9SciTech Premium Collection
10ProQuest Central Essentials
11ProQuest One Academic
prefilterarticles
rsrctypearticles
creatorcontrib
0Justice, Anne
1Karaderi, Tugce
2Highland, Heather
3Young, Kristin
4Graff, Mariaelisa
5Lu, Yingchang
6Auer, Paul
7Fine, Rebecca
8Guo, Xiuqing
9Schurmann, Claudia
10Lempradl, Adelheid
11Marouli, Eirini
12Mahajan, Anubha
13Winkler, Thomas
14Locke, Adam
15Medina-Gomez, Carolina
16Vedantam, Sailaja
17Giri, Ayush
18Mudgal, Poorva
19Ng, Maggie
20Heard-Costa, Nancy
21Feitosa, Mary
22Manning, Alisa
23Willems, Sara
24Sivapalaratnam, Suthesh
25Abecasis, Goncalo
26Alam, Dewan
27Allison, Matthew
28Amouyel, Philippe
29Arzumanyan, Zorayr
30Balkau, Beverley
31Bastarache, Lisa
32Bergmann, Sven
33Bielak, Lawrence
34Boehnke, Michael
35Boeing, Heiner
36Boerwinkle, Eric
37Bork-Jensen, Jette
38Bottinger, Erwin
39Bowden, Donald
40Brandslund, Ivan
41Broer, Linda
42Burt, Amber
43Butterworth, Adam
44Caulfield, Mark
45Cesana, Giancarlo
46Chambers, John
47Chasman, Daniel
48Chen, Yii-Der
49Chowdhury, Rajiv
50Chu, Audrey
51Collins, Francis
52Cook, James
53Cox, Amanda
54Crosslin, David
55Danesh, John
56Dedoussis, George
57Demerath, Ellen
58Dennis, Joe
59Denny, Josh
60Drenos, Fotios
61Dunning, Alison
62Easton, Douglas
63Elliott, Paul
64Evangelou, Evangelos
65Feng, Shuang
66Ferrannini, Ele
67Ferrieres, Jean
68Florez, Jose
69Fornage, Myriam
70Fox, Caroline
71Franks, Paul
72Friedrich, Nele
73Gan, Wei
74Gandin, Ilaria
75Gasparini, Paolo
76Giedraitis, Vilmantas
77Girotto, Giorgia
78Gorski, Mathias
79Grallert, Harald
80Grarup, Niels
81Grove, Megan
82Gustafsson, Stefan
83Haessler, Jeff
84Hansen, Torben
85Hattersley, Andrew
86Hayward, Caroline
87Heid, Iris
88Holmen, Oddgeir
89Howson, Joanna
90Hu, Yao
91Yi-Jen, Hung
92Hveem, Kristian
93Ikram, M
94Ingelsson, Erik
95Jackson, Anne
96Jarvik, Gail
97Jia, Yucheng
98Jousilahti, Pekka
99Justesen, Johanne
100...
jtitleBioRxiv
delivery
delcategoryRemote Search Resource
fulltextfulltext_linktorsrc
addata
aulast
0Justice
1Karaderi
2Highland
3Young
4Graff
5Lu
6Auer
7Fine
8Guo
9Schurmann
10Lempradl
11Marouli
12Mahajan
13Winkler
14Locke
15Medina-Gomez
16Vedantam
17Giri
18Mudgal
19Ng
20Heard-Costa
21Feitosa
22Manning
23Willems
24Sivapalaratnam
25Abecasis
26Alam
27Allison
28Amouyel
29Arzumanyan
30Balkau
31Bastarache
32Bergmann
33Bielak
34Boehnke
35Boeing
36Boerwinkle
37Bork-Jensen
38Bottinger
39Bowden
40Brandslund
41Broer
42Burt
43Butterworth
44Caulfield
45Cesana
46Chambers
47Chasman
48Chen
49Chowdhury
50Chu
51Collins
52Cook
53Cox
54Crosslin
55Danesh
56Dedoussis
57Demerath
58Dennis
59Denny
60Drenos
61Dunning
62Easton
63Elliott
64Evangelou
65Feng
66Ferrannini
67Ferrieres
68Florez
69Fornage
70Fox
71Franks
72Friedrich
73Gan
74Gandin
75Gasparini
76Giedraitis
77Girotto
78Gorski
79Grallert
80Grarup
81Grove
82Gustafsson
83Haessler
84Hansen
85Hattersley
86Hayward
87Heid
88Holmen
89Howson
90Hu
91Yi-Jen
92Hveem
93Ikram
94Ingelsson
95Jackson
96Jarvik
97Jia
98Jousilahti
99Justesen
100...
aufirst
0Anne
1Tugce
2Heather
3Kristin
4Mariaelisa
5Yingchang
6Paul
7Rebecca
8Xiuqing
9Claudia
10Adelheid
11Eirini
12Anubha
13Thomas
14Adam
15Carolina
16Sailaja
17Ayush
18Poorva
19Maggie
20Nancy
21Mary
22Alisa
23Sara
24Suthesh
25Goncalo
26Dewan
27Matthew
28Philippe
29Zorayr
30Beverley
31Lisa
32Sven
33Lawrence
34Michael
35Heiner
36Eric
37Jette
38Erwin
39Donald
40Ivan
41Linda
42Amber
43Mark
44Giancarlo
45John
46Daniel
47Yii-Der
48Rajiv
49Audrey
50Francis
51James
52Amanda
53David
54George
55Ellen
56Joe
57Josh
58Fotios
59Alison
60Douglas
61Evangelos
62Shuang
63Ele
64Jean
65Jose
66Myriam
67Caroline
68Nele
69Wei
70Ilaria
71Paolo
72Vilmantas
73Giorgia
74Mathias
75Harald
76Niels
77Megan
78Stefan
79Jeff
80Torben
81Andrew
82Iris
83Oddgeir
84Joanna
85Yao
86Hung
87Kristian
88M
89Erik
90Gail
91Yucheng
92Pekka
93Johanne
94Bratati
95Maria
96Sharon
97Fredrik
98Frank
99Hidetoshi
100...
au
0Justice, Anne
1Karaderi, Tugce
2Highland, Heather
3Young, Kristin
4Graff, Mariaelisa
5Lu, Yingchang
6Auer, Paul
7Fine, Rebecca
8Guo, Xiuqing
9Schurmann, Claudia
10Lempradl, Adelheid
11Marouli, Eirini
12Mahajan, Anubha
13Winkler, Thomas
14Locke, Adam
15Medina-Gomez, Carolina
16Vedantam, Sailaja
17Giri, Ayush
18Mudgal, Poorva
19Ng, Maggie
20Heard-Costa, Nancy
21Feitosa, Mary
22Manning, Alisa
23Willems, Sara
24Sivapalaratnam, Suthesh
25Abecasis, Goncalo
26Alam, Dewan
27Allison, Matthew
28Amouyel, Philippe
29Arzumanyan, Zorayr
30Balkau, Beverley
31Bastarache, Lisa
32Bergmann, Sven
33Bielak, Lawrence
34Boehnke, Michael
35Boeing, Heiner
36Boerwinkle, Eric
37Bork-Jensen, Jette
38Bottinger, Erwin
39Bowden, Donald
40Brandslund, Ivan
41Broer, Linda
42Burt, Amber
43Butterworth, Adam
44Caulfield, Mark
45Cesana, Giancarlo
46Chambers, John
47Chasman, Daniel
48Chen, Yii-Der
49Chowdhury, Rajiv
50Chu, Audrey
51Collins, Francis
52Cook, James
53Cox, Amanda
54Crosslin, David
55Danesh, John
56Dedoussis, George
57Demerath, Ellen
58Dennis, Joe
59Denny, Josh
60Drenos, Fotios
61Dunning, Alison
62Easton, Douglas
63Elliott, Paul
64Evangelou, Evangelos
65Feng, Shuang
66Ferrannini, Ele
67Ferrieres, Jean
68Florez, Jose
69Fornage, Myriam
70Fox, Caroline
71Franks, Paul
72Friedrich, Nele
73Gan, Wei
74Gandin, Ilaria
75Gasparini, Paolo
76Giedraitis, Vilmantas
77Girotto, Giorgia
78Gorski, Mathias
79Grallert, Harald
80Grarup, Niels
81Grove, Megan
82Gustafsson, Stefan
83Haessler, Jeff
84Hansen, Torben
85Hattersley, Andrew
86Hayward, Caroline
87Heid, Iris
88Holmen, Oddgeir
89Howson, Joanna
90Hu, Yao
91Yi-Jen, Hung
92Hveem, Kristian
93Ikram, M
94Ingelsson, Erik
95Jackson, Anne
96Jarvik, Gail
97Jia, Yucheng
98Jousilahti, Pekka
99Justesen, Johanne
100...
atitlePROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION
jtitleBioRxiv
risdate20180630
formatjournal
genrearticle
ristypeJOUR
abstractBody fat distribution is a heritable risk factor for a range of adverse health consequences, including hyperlipidemia and type 2 diabetes. To identify protein-coding variants associated with body fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, we analyzed 228,985 predicted...
copCold Spring Harbor
pubCold Spring Harbor Laboratory Press
doi10.1101/352674
urlhttp://search.proquest.com/docview/2068577275/
oafree_for_read
date2018-06-30