schliessen

Filtern

 

Bibliotheken

Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria

Recent studies described several different routes that facilitate nitrogen–nitrogen bond formation in natural product biosynthesis. We report herein the identification of unprecedented machinery for hydrazine formation involved in the biosynthesis of s56-p1, a dipeptide natural product with a unique... Full description

Journal Title: Journal of the American Chemical Society 2018-07-25, Vol.140 (29), p.9083-9086
Main Author: Matsuda, Kenichi
Other Authors: Tomita, Takeo , Shin-ya, Kazuo , Wakimoto, Toshiyuki , Kuzuyama, Tomohisa , Nishiyama, Makoto
Format: Electronic Article Electronic Article
Language: English
Publisher: United States: American Chemical Society
ID: ISSN: 0002-7863
Link: https://www.ncbi.nlm.nih.gov/pubmed/30001119
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: cdi_proquest_miscellaneous_2070241983
title: Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria
format: Article
creator:
  • Matsuda, Kenichi
  • Tomita, Takeo
  • Shin-ya, Kazuo
  • Wakimoto, Toshiyuki
  • Kuzuyama, Tomohisa
  • Nishiyama, Makoto
ispartof: Journal of the American Chemical Society, 2018-07-25, Vol.140 (29), p.9083-9086
description: Recent studies described several different routes that facilitate nitrogen–nitrogen bond formation in natural product biosynthesis. We report herein the identification of unprecedented machinery for hydrazine formation involved in the biosynthesis of s56-p1, a dipeptide natural product with a unique hydrazone unit. The gene cassette comprising this machinery is widespread across several bacterial phyla, highlighting the overlooked potential of bacteria to synthesize hydrazine.
language: eng
source:
identifier: ISSN: 0002-7863
fulltext: no_fulltext
issn:
  • 0002-7863
  • 1520-5126
url: Link


@attributes
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
RANK1.9424733
LOCALfalse
PrimoNMBib
record
control
sourceidproquest_cross
recordidTN_cdi_proquest_miscellaneous_2070241983
sourceformatXML
sourcesystemPC
sourcerecordid2070241983
originalsourceidFETCH-LOGICAL-a4191-1c65c23acac3ab89afdcc5e14d4d1fffcb897ac054a40108a1aade7b00eda3020
addsrcrecordideNptkE1PwkAQhjdGI4jePJsePVic2XZpOQqKmGC8yLmZ7k61hLa425rgr3cJqBdP85Fn3pl5hbhEGCJIvF2RdsM0BxWp-Ej0UUkIFcrRsegDgAyTdBT1xJlzK1_GMsVT0Yt8iojjvpjcl043n2y3QVMEy3pjWbPhumUTzLfG0ldZczhrbFXWb8Ez6Xdfe7isgwnplm1J5-KkoLXji0MciOXs4XU6Dxcvj0_Tu0VIMY4xRD1SWkakSUeUp2MqjNaKMTaxwaIotO8lpEHFFANCSkhkOMkB2FAEEgbieq-7sc1Hx67NKn87r9dUc9O5TEIC0q9KI4_e7FFtG-csF9nGlhXZbYaQ7VzLdq5lB9c8fnVQ7vKKzS_8Y9Pf6t3Uquls7R_9X-sbT6d19w
sourcetypeAggregation Database
isCDItrue
recordtypearticle
pqid2070241983
display
typearticle
titleDiscovery of Unprecedented Hydrazine-Forming Machinery in Bacteria
creatorMatsuda, Kenichi ; Tomita, Takeo ; Shin-ya, Kazuo ; Wakimoto, Toshiyuki ; Kuzuyama, Tomohisa ; Nishiyama, Makoto
creatorcontribMatsuda, Kenichi ; Tomita, Takeo ; Shin-ya, Kazuo ; Wakimoto, Toshiyuki ; Kuzuyama, Tomohisa ; Nishiyama, Makoto
descriptionRecent studies described several different routes that facilitate nitrogen–nitrogen bond formation in natural product biosynthesis. We report herein the identification of unprecedented machinery for hydrazine formation involved in the biosynthesis of s56-p1, a dipeptide natural product with a unique hydrazone unit. The gene cassette comprising this machinery is widespread across several bacterial phyla, highlighting the overlooked potential of bacteria to synthesize hydrazine.
identifier
0ISSN: 0002-7863
1EISSN: 1520-5126
2DOI: 10.1021/jacs.8b05354
3PMID: 30001119
languageeng
publisherUnited States: American Chemical Society
ispartofJournal of the American Chemical Society, 2018-07-25, Vol.140 (29), p.9083-9086
orcidid0000-0002-7221-5858 ; 0000-0001-8143-8052 ; 0000-0003-2917-1797
links
openurl$$Topenurl_article
thumbnail$$Usyndetics_thumb_exl
backlink$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30001119$$D View this record in MEDLINE/PubMed
search
creatorcontrib
0Matsuda, Kenichi
1Tomita, Takeo
2Shin-ya, Kazuo
3Wakimoto, Toshiyuki
4Kuzuyama, Tomohisa
5Nishiyama, Makoto
title
0Discovery of Unprecedented Hydrazine-Forming Machinery in Bacteria
1Journal of the American Chemical Society
addtitleJ. Am. Chem. Soc
descriptionRecent studies described several different routes that facilitate nitrogen–nitrogen bond formation in natural product biosynthesis. We report herein the identification of unprecedented machinery for hydrazine formation involved in the biosynthesis of s56-p1, a dipeptide natural product with a unique hydrazone unit. The gene cassette comprising this machinery is widespread across several bacterial phyla, highlighting the overlooked potential of bacteria to synthesize hydrazine.
issn
00002-7863
11520-5126
fulltextfalse
rsrctypearticle
creationdate2018
recordtypearticle
recordideNptkE1PwkAQhjdGI4jePJsePVic2XZpOQqKmGC8yLmZ7k61hLa425rgr3cJqBdP85Fn3pl5hbhEGCJIvF2RdsM0BxWp-Ej0UUkIFcrRsegDgAyTdBT1xJlzK1_GMsVT0Yt8iojjvpjcl043n2y3QVMEy3pjWbPhumUTzLfG0ldZczhrbFXWb8Ez6Xdfe7isgwnplm1J5-KkoLXji0MciOXs4XU6Dxcvj0_Tu0VIMY4xRD1SWkakSUeUp2MqjNaKMTaxwaIotO8lpEHFFANCSkhkOMkB2FAEEgbieq-7sc1Hx67NKn87r9dUc9O5TEIC0q9KI4_e7FFtG-csF9nGlhXZbYaQ7VzLdq5lB9c8fnVQ7vKKzS_8Y9Pf6t3Uquls7R_9X-sbT6d19w
startdate20180725
enddate20180725
creator
0Matsuda, Kenichi
1Tomita, Takeo
2Shin-ya, Kazuo
3Wakimoto, Toshiyuki
4Kuzuyama, Tomohisa
5Nishiyama, Makoto
generalAmerican Chemical Society
scope
0NPM
1AAYXX
2CITATION
37X8
orcidid
0https://orcid.org/0000-0002-7221-5858
1https://orcid.org/0000-0001-8143-8052
2https://orcid.org/0000-0003-2917-1797
sort
creationdate20180725
titleDiscovery of Unprecedented Hydrazine-Forming Machinery in Bacteria
authorMatsuda, Kenichi ; Tomita, Takeo ; Shin-ya, Kazuo ; Wakimoto, Toshiyuki ; Kuzuyama, Tomohisa ; Nishiyama, Makoto
facets
frbrtype5
frbrgroupidcdi_FETCH-LOGICAL-a4191-1c65c23acac3ab89afdcc5e14d4d1fffcb897ac054a40108a1aade7b00eda3020
rsrctypearticles
prefilterarticles
languageeng
creationdate2018
creatorcontrib
0Matsuda, Kenichi
1Tomita, Takeo
2Shin-ya, Kazuo
3Wakimoto, Toshiyuki
4Kuzuyama, Tomohisa
5Nishiyama, Makoto
collection
0PubMed
1CrossRef
2MEDLINE - Academic
jtitleJournal of the American Chemical Society
delivery
delcategoryRemote Search Resource
fulltextno_fulltext
addata
au
0Matsuda, Kenichi
1Tomita, Takeo
2Shin-ya, Kazuo
3Wakimoto, Toshiyuki
4Kuzuyama, Tomohisa
5Nishiyama, Makoto
formatjournal
genrearticle
ristypeJOUR
atitleDiscovery of Unprecedented Hydrazine-Forming Machinery in Bacteria
jtitleJournal of the American Chemical Society
addtitleJ. Am. Chem. Soc
date2018-07-25
risdate2018
volume140
issue29
spage9083
epage9086
pages9083-9086
issn0002-7863
eissn1520-5126
abstractRecent studies described several different routes that facilitate nitrogen–nitrogen bond formation in natural product biosynthesis. We report herein the identification of unprecedented machinery for hydrazine formation involved in the biosynthesis of s56-p1, a dipeptide natural product with a unique hydrazone unit. The gene cassette comprising this machinery is widespread across several bacterial phyla, highlighting the overlooked potential of bacteria to synthesize hydrazine.
copUnited States
pubAmerican Chemical Society
pmid30001119
doi10.1021/jacs.8b05354
orcidid
0https://orcid.org/0000-0002-7221-5858
1https://orcid.org/0000-0001-8143-8052
2https://orcid.org/0000-0003-2917-1797