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Transdifferentiation of human adult peripheral blood T cells into neurons

Human cell models for disease based on induced pluripotent stem (iPS) cells have proven to be powerful new assets for investigating disease mechanisms. New insights have been obtained studying single mutations using isogenic controls generated by gene...

Journal Title: Proceedings of the National Academy of Sciences of the United States of America Jun 19, 2018, Vol.115(25), p.6470
Main Author: Tanabe, Koji
Other Authors: Ang, Cheen , Chanda, Soham , Olmos, Victor , Haag, Daniel , Levinson, Douglas , Südhof, Thomas , Wernig, Marius
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 00278424 ; E-ISSN: 10916490
Link: http://search.proquest.com/docview/2099983984/?pq-origsite=primo
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title: Transdifferentiation of human adult peripheral blood T cells into neurons
format: Article
creator:
  • Tanabe, Koji
  • Ang, Cheen
  • Chanda, Soham
  • Olmos, Victor
  • Haag, Daniel
  • Levinson, Douglas
  • Südhof, Thomas
  • Wernig, Marius
subjects:
  • Blood
  • Stem Cells
  • Neurons
  • Nervous System
  • Gene Expression
  • Neurons
  • Immunological Synapses
  • Blood
  • Neurogenesis
  • Blood
  • Morphology
  • Interrogation
  • Lymphocytes T
  • Cell Culture
  • Fibroblasts
  • Peripheral Blood Mononuclear Cells
  • Skin
  • Variability
  • Lymphocytes
  • Gene Targeting
ispartof: Proceedings of the National Academy of Sciences of the United States of America, Jun 19, 2018, Vol.115(25), p.6470
description: Human cell models for disease based on induced pluripotent stem (iPS) cells have proven to be powerful new assets for investigating disease mechanisms. New insights have been obtained studying single mutations using isogenic controls generated by gene...
language: eng
source:
identifier: ISSN: 00278424 ; E-ISSN: 10916490
fulltext: fulltext
issn:
  • 00278424
  • 0027-8424
  • 10916490
  • 1091-6490
url: Link


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titleTransdifferentiation of human adult peripheral blood T cells into neurons
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identifierISSN: 00278424 ; E-ISSN: 10916490
subjectBlood ; Stem Cells ; Neurons ; Nervous System ; Gene Expression ; Neurons ; Immunological Synapses ; Blood ; Neurogenesis ; Blood ; Morphology ; Interrogation ; Lymphocytes T ; Cell Culture ; Fibroblasts ; Peripheral Blood Mononuclear Cells ; Skin ; Variability ; Lymphocytes ; Gene Targeting
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titleTransdifferentiation of human adult peripheral blood T cells into neurons
authorTanabe, Koji ; Ang, Cheen ; Chanda, Soham ; Olmos, Victor ; Haag, Daniel ; Levinson, Douglas ; Südhof, Thomas ; Wernig, Marius
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abstractHuman cell models for disease based on induced pluripotent stem (iPS) cells have proven to be powerful new assets for investigating disease mechanisms. New insights have been obtained studying single mutations using isogenic controls generated by gene...
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pubNational Academy of Sciences
urlhttp://search.proquest.com/docview/2099983984/
pages6470-6475
doi10.1073/pnas.1720273115
date2018-06-19