schliessen

Filtern

 

Bibliotheken

Monounsaturated Fat and Cardiovascular Risk

On the basis of the information discussed in this review, we can conclude that the effects of a high intake of monounsaturated fatty acids (MUFA) from olive oil include a wide range of healthy benefits beyond improvement in cholesterol levels, suggesting that this type of diet has great potential in... Full description

Journal Title: Nutrition Reviews Oct 2006, Vol.64(10), pp.S2-S12
Main Author: López-Miranda, Jose
Other Authors: Badimon, Lina , Bonanome, Andrea , Lairon, Denis
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 00296643
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: proquest212322670
title: Monounsaturated Fat and Cardiovascular Risk
format: Article
creator:
  • López-Miranda, Jose
  • Badimon, Lina
  • Bonanome, Andrea
  • Lairon, Denis
subjects:
  • Diet
  • Diabetes
  • Cholesterol
  • Nutrition
  • Cardiovascular Disease
  • Fatty Acids
  • Oils & Fats
ispartof: Nutrition Reviews, Oct 2006, Vol.64(10), pp.S2-S12
description: On the basis of the information discussed in this review, we can conclude that the effects of a high intake of monounsaturated fatty acids (MUFA) from olive oil include a wide range of healthy benefits beyond improvement in cholesterol levels, suggesting that this type of diet has great potential in preventing cardiovascular disease. MUFA-enriched diets reduce insulin requirements and decrease plasma concentrations of glucose and insulin in type 2 diabetic patients, unlike high-saturated fatty acid and low-fat, high-carbohydrate diets. Moreover, some data show that this dietary model could have a hypotensive effect. There is also substantial evidence that oleic-enriched low-density lipoprotein (LDL) is more resistant to oxidative modifications and that dietary MUFA may influence various components and functions related to the endothelium. These include endothelium-dependent vasodilatation and a reduced capacity of oleic-enriched LDL to promote the adhesion and chemotaxis of monocytes. On the other hand, a MUFA diet decreases the prothrombotic environment, modifying platelet adhesion, coagulation, and fibrinolysis. Its reducing effect on PAI-1 plasma levels is of particular relevance. This wide range of anti-atherogenic effects could explain the low rate of cardiovascular mortality found in Mediterranean countries, where there is a moderate to high supply of dietary MUFA. Future studies need to focus on uncovering the mechanisms by which the Mediterranean diet exerts its beneficial effects. [PUBLICATION ]
language: eng
source:
identifier: ISSN: 00296643
fulltext: fulltext
issn:
  • 00296643
  • 0029-6643
url: Link


@attributes
ID809286606
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid212322670
sourceidproquest
recordidTN_proquest212322670
sourcesystemOther
pqid212322670
galeid153897836
display
typearticle
titleMonounsaturated Fat and Cardiovascular Risk
creatorLópez-Miranda, Jose ; Badimon, Lina ; Bonanome, Andrea ; Lairon, Denis
ispartofNutrition Reviews, Oct 2006, Vol.64(10), pp.S2-S12
identifierISSN: 00296643
subjectDiet ; Diabetes ; Cholesterol ; Nutrition ; Cardiovascular Disease ; Fatty Acids ; Oils & Fats
descriptionOn the basis of the information discussed in this review, we can conclude that the effects of a high intake of monounsaturated fatty acids (MUFA) from olive oil include a wide range of healthy benefits beyond improvement in cholesterol levels, suggesting that this type of diet has great potential in preventing cardiovascular disease. MUFA-enriched diets reduce insulin requirements and decrease plasma concentrations of glucose and insulin in type 2 diabetic patients, unlike high-saturated fatty acid and low-fat, high-carbohydrate diets. Moreover, some data show that this dietary model could have a hypotensive effect. There is also substantial evidence that oleic-enriched low-density lipoprotein (LDL) is more resistant to oxidative modifications and that dietary MUFA may influence various components and functions related to the endothelium. These include endothelium-dependent vasodilatation and a reduced capacity of oleic-enriched LDL to promote the adhesion and chemotaxis of monocytes. On the other hand, a MUFA diet decreases the prothrombotic environment, modifying platelet adhesion, coagulation, and fibrinolysis. Its reducing effect on PAI-1 plasma levels is of particular relevance. This wide range of anti-atherogenic effects could explain the low rate of cardiovascular mortality found in Mediterranean countries, where there is a moderate to high supply of dietary MUFA. Future studies need to focus on uncovering the mechanisms by which the Mediterranean diet exerts its beneficial effects. [PUBLICATION ]
languageeng
source
version5
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
linktorsrc$$Uhttp://search.proquest.com/docview/212322670/?pq-origsite=primo$$EView_record_in_ProQuest_(subscribers_only)
search
creatorcontrib
0López-Miranda, Jose
1Badimon, Lina
2Bonanome, Andrea
3Lairon, Denis
titleMonounsaturated Fat and Cardiovascular Risk
descriptionOn the basis of the information discussed in this review, we can conclude that the effects of a high intake of monounsaturated fatty acids (MUFA) from olive oil include a wide range of healthy benefits beyond improvement in cholesterol levels, suggesting that this type of diet has great potential in preventing cardiovascular disease. MUFA-enriched diets reduce insulin requirements and decrease plasma concentrations of glucose and insulin in type 2 diabetic patients, unlike high-saturated fatty acid and low-fat, high-carbohydrate diets. Moreover, some data show that this dietary model could have a hypotensive effect. There is also substantial evidence that oleic-enriched low-density lipoprotein (LDL) is more resistant to oxidative modifications and that dietary MUFA may influence various components and functions related to the endothelium. These include endothelium-dependent vasodilatation and a reduced capacity of oleic-enriched LDL to promote the adhesion and chemotaxis of monocytes. On the other hand, a MUFA diet decreases the prothrombotic environment, modifying platelet adhesion, coagulation, and fibrinolysis. Its reducing effect on PAI-1 plasma levels is of particular relevance. This wide range of anti-atherogenic effects could explain the low rate of cardiovascular mortality found in Mediterranean countries, where there is a moderate to high supply of dietary MUFA. Future studies need to focus on uncovering the mechanisms by which the Mediterranean diet exerts its beneficial effects. [PUBLICATION ]
subject
0Diet
1Diabetes
2Cholesterol
3Nutrition
4Cardiovascular Disease
5Fatty Acids
6Oils & Fats
general
0English
1Oxford University Press, UK
2Medical Database
3ProQuest Science Journals
4Consumer Health Database
5Health & Medical Collection (Alumni edition)
6Medical Database (Alumni edition)
7Nursing & Allied Health Database (Alumni edition)
8Science Database (Alumni edition)
9ProQuest Pharma Collection
10Health & Medical Collection
11Nursing & Allied Health Database
12ProQuest Agriculture Journals
13ProQuest Public Health
14Family Health Database (Alumni edition)
15Research Library China
16ProQuest Nursing & Allied Health Source
17ProQuest Research Library
18ProQuest Discovery
19ProQuest Agricultural Science Collection
20ProQuest Central
21ProQuest Hospital Collection
22ProQuest Natural Science Collection
23Research Library (Alumni edition)
24Hospital Premium Collection (Alumni edition)
25ProQuest SciTech Collection
26ProQuest Health & Medical Complete
27ProQuest Medical Library
28Agricultural & Environmental Science Database
29Natural Science Collection
30ProQuest Central (new)
31ProQuest Central K-12
32ProQuest Central Korea
33Research Library Prep
34SciTech Premium Collection
35Health Research Premium Collection
36Health Research Premium Collection (Alumni edition)
37ProQuest Central Essentials
38eLibrary
39ProQuest Central China
sourceidproquest
recordidproquest212322670
issn
000296643
10029-6643
rsrctypearticle
creationdate2006
addtitleNutrition Reviews
searchscope
01000273
11000283
21005660
31006454
41006520
51006759
61006761
71006762
81006763
91006765
101006815
111006993
121007015
131007067
141007107
151007160
161007617
171007899
181007906
191007945
201008005
211008174
221008886
231009127
241009191
251009384
2610000020
2710000025
2810000027
2910000034
3010000035
3110000039
3210000047
3310000050
3410000064
3510000117
3610000118
3710000119
3810000120
3910000155
4010000156
4110000157
4210000158
4310000164
4410000234
4510000253
4610000255
4710000256
4810000257
4910000258
5010000259
5110000260
5210000270
5310000271
5410000281
5510000293
5610000300
57proquest
scope
01000273
11000283
21005660
31006454
41006520
51006759
61006761
71006762
81006763
91006765
101006815
111006993
121007015
131007067
141007107
151007160
161007617
171007899
181007906
191007945
201008005
211008174
221008886
231009127
241009191
251009384
2610000020
2710000025
2810000027
2910000034
3010000035
3110000039
3210000047
3310000050
3410000064
3510000117
3610000118
3710000119
3810000120
3910000155
4010000156
4110000157
4210000158
4310000164
4410000234
4510000253
4610000255
4710000256
4810000257
4910000258
5010000259
5110000260
5210000270
5310000271
5410000281
5510000293
5610000300
57proquest
lsr43
01000273true
11000283true
21005660true
31006454true
41006520true
51006759true
61006761true
71006762true
81006763true
91006765true
101006815true
111006993true
121007015true
131007067true
141007107true
151007160true
161007617true
171007899true
181007906true
191007945true
201008005true
211008174true
221008886true
231009127true
241009191true
251009384true
2610000020true
2710000025true
2810000027true
2910000034true
3010000035true
3110000039true
3210000047true
3310000050true
3410000064true
3510000117true
3610000118true
3710000119true
3810000120true
3910000155true
4010000156true
4110000157true
4210000158true
4310000164true
4410000234true
4510000253true
4610000255true
4710000256true
4810000257true
4910000258true
5010000259true
5110000260true
5210000270true
5310000271true
5410000281true
5510000293true
5610000300true
startdate20061001
enddate20061001
citationpf S2 pt S12 vol 64 issue 10
lsr30VSR-Enriched:[pqid, doi, galeid]
sort
titleMonounsaturated Fat and Cardiovascular Risk
authorLópez-Miranda, Jose ; Badimon, Lina ; Bonanome, Andrea ; Lairon, Denis
creationdate20061001
lso0120061001
facets
frbrgroupid5665703703454508010
frbrtype5
newrecords20180321
languageeng
creationdate2006
topic
0Diet
1Diabetes
2Cholesterol
3Nutrition
4Cardiovascular Disease
5Fatty Acids
6Oils & Fats
collection
0Medical Database
1ProQuest Science Journals
2Consumer Health Database
3Health & Medical Collection (Alumni edition)
4Medical Database (Alumni edition)
5Nursing & Allied Health Database (Alumni edition)
6Science Database (Alumni edition)
7ProQuest Pharma Collection
8Health & Medical Collection
9Nursing & Allied Health Database
10ProQuest Agriculture Journals
11ProQuest Public Health
12Family Health Database (Alumni edition)
13Research Library China
14ProQuest Nursing & Allied Health Source
15ProQuest Research Library
16ProQuest Discovery
17ProQuest Agricultural Science Collection
18ProQuest Central
19ProQuest Hospital Collection
20ProQuest Natural Science Collection
21Research Library (Alumni edition)
22Hospital Premium Collection (Alumni edition)
23ProQuest SciTech Collection
24ProQuest Health & Medical Complete
25ProQuest Medical Library
26Agricultural & Environmental Science Database
27Natural Science Collection
28ProQuest Central (new)
29ProQuest Central K-12
30ProQuest Central Korea
31Research Library Prep
32SciTech Premium Collection
33Health Research Premium Collection
34Health Research Premium Collection (Alumni edition)
35ProQuest Central Essentials
36eLibrary
37ProQuest Central China
prefilterarticles
rsrctypearticles
creatorcontrib
0López-Miranda, Jose
1Badimon, Lina
2Bonanome, Andrea
3Lairon, Denis
jtitleNutrition Reviews
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0López-Miranda
1Badimon
2Bonanome
3Lairon
aufirst
0Jose
1Lina
2Andrea
3Denis
au
0López-Miranda, Jose
1Badimon, Lina
2Bonanome, Andrea
3Lairon, Denis
atitleMonounsaturated Fat and Cardiovascular Risk
jtitleNutrition Reviews
risdate20061001
volume64
issue10
spageS2
epageS12
pagesS2-S12
issn00296643
formatjournal
genrearticle
ristypeJOUR
abstractOn the basis of the information discussed in this review, we can conclude that the effects of a high intake of monounsaturated fatty acids (MUFA) from olive oil include a wide range of healthy benefits beyond improvement in cholesterol levels, suggesting that this type of diet has great potential in preventing cardiovascular disease. MUFA-enriched diets reduce insulin requirements and decrease plasma concentrations of glucose and insulin in type 2 diabetic patients, unlike high-saturated fatty acid and low-fat, high-carbohydrate diets. Moreover, some data show that this dietary model could have a hypotensive effect. There is also substantial evidence that oleic-enriched low-density lipoprotein (LDL) is more resistant to oxidative modifications and that dietary MUFA may influence various components and functions related to the endothelium. These include endothelium-dependent vasodilatation and a reduced capacity of oleic-enriched LDL to promote the adhesion and chemotaxis of monocytes. On the other hand, a MUFA diet decreases the prothrombotic environment, modifying platelet adhesion, coagulation, and fibrinolysis. Its reducing effect on PAI-1 plasma levels is of particular relevance. This wide range of anti-atherogenic effects could explain the low rate of cardiovascular mortality found in Mediterranean countries, where there is a moderate to high supply of dietary MUFA. Future studies need to focus on uncovering the mechanisms by which the Mediterranean diet exerts its beneficial effects. [PUBLICATION ABSTRACT]
copOxford
pubOxford University Press, UK
urlhttp://search.proquest.com/docview/212322670/
doi10.1301/nr.2006.oct.S2-S12
date2006-10-01