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Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial

OBJECTIVE The long-term impact of intentional weight loss on cardiovascular events remains unknown. We describe 12-month changes in body weight and cardiovascular risk factors in PREvención con DIeta MEDiterránea (PREDIMED)-Plus, a trial designed to evaluate the long-term effectiveness of an intensi... Full description

Journal Title: Diabetes Care May 1, 2019, Vol.42(5), p.777
Main Author: Salas-Salvadó, Jordi
Other Authors: Díaz-López, Andrés , Ruiz-Canela, Miguel , Basora, Josep , Fitó, Montse , Corella, Dolores , Serra-Majem, Luís , Wärnberg, Julia , Romaguera, Dora , Estruch, Ramon , Vidal, Josep , Martínez
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 01495992 ; DOI: 10.2337/dc18-0836
Link: http://search.proquest.com/docview/2224340772/?pq-origsite=primo
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title: Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial
format: Article
creator:
  • Salas-Salvadó, Jordi
  • Díaz-López, Andrés
  • Ruiz-Canela, Miguel
  • Basora, Josep
  • Fitó, Montse
  • Corella, Dolores
  • Serra-Majem, Luís
  • Wärnberg, Julia
  • Romaguera, Dora
  • Estruch, Ramon
  • Vidal, Josep
  • Martínez
subjects:
  • Triglycerides
  • Insulin
  • Diabetes
  • Physical Activity
  • Nutrient Deficiency
  • Cholesterol
  • Monocyte Chemoattractant Protein 1
  • Leptin
  • Triglycerides
  • Elderly People
  • Metabolic Disorders
  • Interleukin 18
  • Cholesterol
  • Diet
  • Metabolic Disorders
  • Risk Analysis
  • Body Weight
  • Immunoglobulins
  • Insulin
  • Metabolic Disorders
ispartof: Diabetes Care, May 1, 2019, Vol.42(5), p.777
description: OBJECTIVE The long-term impact of intentional weight loss on cardiovascular events remains unknown. We describe 12-month changes in body weight and cardiovascular risk factors in PREvención con DIeta MEDiterránea (PREDIMED)-Plus, a trial designed to evaluate the long-term effectiveness of an intensive weight loss lifestyle intervention on primary cardiovascular prevention. RESEARCH DESIGN AND METHODS Overweight/obese adults with metabolic syndrome aged 55–75 years (n = 626) were randomized to an intensive weight loss lifestyle intervention based on an energy-restricted Mediterranean diet, physical activity promotion, and behavioral support (IG) or a control group (CG). The primary and secondary outcomes were changes in weight and cardiovascular risk markers, respectively. RESULTS Diet and physical activity changes were in the expected direction, with significant improvements in IG versus CG. After 12 months, IG participants lost an average of 3.2 kg vs. 0.7 kg in the CG (P < 0.001), a mean...
language: eng
source:
identifier: ISSN: 01495992 ; DOI: 10.2337/dc18-0836
fulltext: fulltext
issn:
  • 01495992
  • 0149-5992
url: Link


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titleEffect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial
creatorSalas-Salvadó, Jordi ; Díaz-López, Andrés ; Ruiz-Canela, Miguel ; Basora, Josep ; Fitó, Montse ; Corella, Dolores ; Serra-Majem, Luís ; Wärnberg, Julia ; Romaguera, Dora ; Estruch, Ramon ; Vidal, Josep ; Martínez
ispartofDiabetes Care, May 1, 2019, Vol.42(5), p.777
identifierISSN: 01495992 ; DOI: 10.2337/dc18-0836
subjectTriglycerides ; Insulin ; Diabetes ; Physical Activity ; Nutrient Deficiency ; Cholesterol ; Monocyte Chemoattractant Protein 1 ; Leptin ; Triglycerides ; Elderly People ; Metabolic Disorders ; Interleukin 18 ; Cholesterol ; Diet ; Metabolic Disorders ; Risk Analysis ; Body Weight ; Immunoglobulins ; Insulin ; Metabolic Disorders
descriptionOBJECTIVE The long-term impact of intentional weight loss on cardiovascular events remains unknown. We describe 12-month changes in body weight and cardiovascular risk factors in PREvención con DIeta MEDiterránea (PREDIMED)-Plus, a trial designed to evaluate the long-term effectiveness of an intensive weight loss lifestyle intervention on primary cardiovascular prevention. RESEARCH DESIGN AND METHODS Overweight/obese adults with metabolic syndrome aged 55–75 years (n = 626) were randomized to an intensive weight loss lifestyle intervention based on an energy-restricted Mediterranean diet, physical activity promotion, and behavioral support (IG) or a control group (CG). The primary and secondary outcomes were changes in weight and cardiovascular risk markers, respectively. RESULTS Diet and physical activity changes were in the expected direction, with significant improvements in IG versus CG. After 12 months, IG participants lost an average of 3.2 kg vs. 0.7 kg in the CG (P < 0.001), a mean...
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titleEffect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial
descriptionOBJECTIVE The long-term impact of intentional weight loss on cardiovascular events remains unknown. We describe 12-month changes in body weight and cardiovascular risk factors in PREvención con DIeta MEDiterránea (PREDIMED)-Plus, a trial designed to evaluate the long-term effectiveness of an intensive weight loss lifestyle intervention on primary cardiovascular prevention. RESEARCH DESIGN AND METHODS Overweight/obese adults with metabolic syndrome aged 55–75 years (n = 626) were randomized to an intensive weight loss lifestyle intervention based on an energy-restricted Mediterranean diet, physical activity promotion, and behavioral support (IG) or a control group (CG). The primary and secondary outcomes were changes in weight and cardiovascular risk markers, respectively. RESULTS Diet and physical activity changes were in the expected direction, with significant improvements in IG versus CG. After 12 months, IG participants lost an average of 3.2 kg vs. 0.7 kg in the CG (P < 0.001), a mean...
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titleEffect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial
authorSalas-Salvadó, Jordi ; Díaz-López, Andrés ; Ruiz-Canela, Miguel ; Basora, Josep ; Fitó, Montse ; Corella, Dolores ; Serra-Majem, Luís ; Wärnberg, Julia ; Romaguera, Dora ; Estruch, Ramon ; Vidal, Josep ; Martínez
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1Insulin
2Diabetes
3Physical Activity
4Nutrient Deficiency
5Cholesterol
6Monocyte Chemoattractant Protein 1
7Leptin
8Elderly People
9Metabolic Disorders
10Interleukin 18
11Diet
12Risk Analysis
13Body Weight
14Immunoglobulins
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35Martínez-González, Miguel
atitleEffect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial
jtitleDiabetes Care
risdate20190501
volume42
issue5
spage777
issn01495992
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abstractOBJECTIVE The long-term impact of intentional weight loss on cardiovascular events remains unknown. We describe 12-month changes in body weight and cardiovascular risk factors in PREvención con DIeta MEDiterránea (PREDIMED)-Plus, a trial designed to evaluate the long-term effectiveness of an intensive weight loss lifestyle intervention on primary cardiovascular prevention. RESEARCH DESIGN AND METHODS Overweight/obese adults with metabolic syndrome aged 55–75 years (n = 626) were randomized to an intensive weight loss lifestyle intervention based on an energy-restricted Mediterranean diet, physical activity promotion, and behavioral support (IG) or a control group (CG). The primary and secondary outcomes were changes in weight and cardiovascular risk markers, respectively. RESULTS Diet and physical activity changes were in the expected direction, with significant improvements in IG versus CG. After 12 months, IG participants lost an average of 3.2 kg vs. 0.7 kg in the CG (P < 0.001), a mean...
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pubAmerican Diabetes Association
doi10.2337/dc18-0836
urlhttp://search.proquest.com/docview/2224340772/
pages777-788
eissn19355548
date2019-05-01