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Pre-clinical evaluation of liposomal gene transfer to improve dermal and epidermal regeneration

Liposomal gene transfer effectively enhances dermal and epidermal regeneration in burned rodents. To advance this treatment to clinical studies, we investigated the efficacy of liposomal gene transfer in a clinically relevant porcine wound model. Mimicking the clinical scenario, six female Yorkshire... Full description

Journal Title: Gene Therapy Jun 2010, pp.770-8
Main Author: Branski, L
Other Authors: Masters, O , Herndon, D , Mittermayr, R , Redl, H , Traber, D , Cox, R , Kita, K , Jeschke, M
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 09697128 ; E-ISSN: 14765462 ; DOI: 10.1038/gt.2010.32
Link: http://search.proquest.com/docview/366305899/?pq-origsite=primo
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recordid: proquest366305899
title: Pre-clinical evaluation of liposomal gene transfer to improve dermal and epidermal regeneration
format: Article
creator:
  • Branski, L
  • Masters, O
  • Herndon, D
  • Mittermayr, R
  • Redl, H
  • Traber, D
  • Cox, R
  • Kita, K
  • Jeschke, M
subjects:
  • Animals–Therapy
  • Burns–Genetics
  • Epidermis–Injuries
  • Female–Methods
  • Gene Transfer Techniques–Genetics
  • Liposomes–Genetics
  • Models, Animal–Genetics
  • Platelet-Derived Growth Factor–Genetics
  • Regeneration–Genetics
  • Skin–Genetics
  • Skin Transplantation–Genetics
  • Swine–Genetics
  • Transfection–Genetics
  • Wound Healing–Genetics
  • Gene Therapy
  • Dermatology
  • Wound Healing
  • Burns
  • Rodents
  • Liposomes
  • Platelet-Derived Growth Factor
ispartof: Gene Therapy, Jun 2010, pp.770-8
description: Liposomal gene transfer effectively enhances dermal and epidermal regeneration in burned rodents. To advance this treatment to clinical studies, we investigated the efficacy of liposomal gene transfer in a clinically relevant porcine wound model. Mimicking the clinical scenario, six female Yorkshire...
language: eng
source:
identifier: ISSN: 09697128 ; E-ISSN: 14765462 ; DOI: 10.1038/gt.2010.32
fulltext: fulltext
issn:
  • 09697128
  • 0969-7128
  • 14765462
  • 1476-5462
url: Link


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titlePre-clinical evaluation of liposomal gene transfer to improve dermal and epidermal regeneration
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subjectAnimals–Therapy ; Burns–Genetics ; Epidermis–Injuries ; Female–Methods ; Gene Transfer Techniques–Genetics ; Liposomes–Genetics ; Models, Animal–Genetics ; Platelet-Derived Growth Factor–Genetics ; Regeneration–Genetics ; Skin–Genetics ; Skin Transplantation–Genetics ; Swine–Genetics ; Transfection–Genetics ; Wound Healing–Genetics ; Gene Therapy ; Dermatology ; Wound Healing ; Burns ; Rodents ; Liposomes ; Platelet-Derived Growth Factor
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titlePre-clinical evaluation of liposomal gene transfer to improve dermal and epidermal regeneration
authorBranski, L ; Masters, O ; Herndon, D ; Mittermayr, R ; Redl, H ; Traber, D ; Cox, R ; Kita, K ; Jeschke, M
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abstractLiposomal gene transfer effectively enhances dermal and epidermal regeneration in burned rodents. To advance this treatment to clinical studies, we investigated the efficacy of liposomal gene transfer in a clinically relevant porcine wound model. Mimicking the clinical scenario, six female Yorkshire...
copHoundmills
pubNature Publishing Group
doi10.1038/gt.2010.32
urlhttp://search.proquest.com/docview/366305899/
issue6
volume17
date2010-06-01