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Circulating oxidized LDL is associated with increased waist circumference independent of body mass index in men and women.

BACKGROUNDObesity is associated with oxidative stress, and the oxidation of LDL is thought to play a crucial role in the generation of atherosclerotic lesions. OBJECTIVEThe objective was to describe the association of waist circumference (WC) and body mass index (BMI; in kg/m2) with plasma circulati... Full description

Journal Title: The American journal of clinical nutrition January 2006, Vol.83(1), pp.30-5; quiz 181-2
Main Author: Weinbrenner, Tanja
Other Authors: Schröder, Helmut , Escurriol, Veronica , Fito, Montserrat , Elosua, Roberto , Vila, Joan , Marrugat, Jaume , Covas, Maria-Isabel
Format: Electronic Article Electronic Article
Language: English
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ID: ISSN: 0002-9165
Link: http://search.proquest.com/docview/67610452/?pq-origsite=primo
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title: Circulating oxidized LDL is associated with increased waist circumference independent of body mass index in men and women.
format: Article
creator:
  • Weinbrenner, Tanja
  • Schröder, Helmut
  • Escurriol, Veronica
  • Fito, Montserrat
  • Elosua, Roberto
  • Vila, Joan
  • Marrugat, Jaume
  • Covas, Maria-Isabel
subjects:
  • Abdominal Fat–Metabolism
  • Adult–Metabolism
  • Aged–Etiology
  • Body Mass Index–Metabolism
  • C-Reactive Protein–Blood
  • Cardiovascular Diseases–Metabolism
  • Cross-Sectional Studies–Etiology
  • Female–Metabolism
  • Humans–Blood
  • Linear Models–Complications
  • Lipoproteins, LDL–Metabolism
  • Logistic Models–Physiology
  • Male–Physiology
  • Metabolic Syndrome–Physiology
  • Middle Aged–Physiology
  • Multivariate Analysis–Physiology
  • Obesity–Physiology
  • Oxidation-Reduction–Physiology
  • Oxidative Stress–Physiology
  • Risk Factors
ispartof: The American journal of clinical nutrition, January 2006, Vol.83(1), pp.30-5; quiz 181-2
description: BACKGROUNDObesity is associated with oxidative stress, and the oxidation of LDL is thought to play a crucial role in the generation of atherosclerotic lesions. OBJECTIVEThe objective was to describe the association of waist circumference (WC) and body mass index (BMI; in kg/m2) with plasma circulating oxidized LDL (ox-LDL) and C-reactive protein (CRP). DESIGNThis cross-sectional study included data for circulating ox-LDL and CRP from a subpopulation of 586 men and women enrolled in a population-based survey conducted in 2000 in Girona, Spain. Multivariate analysis was performed to describe the independent association of WC and BMI with ox-LDL and CRP. RESULTSMultivariate logistic regression analysis adjusted for lifestyle, educational level, and dietary confounders showed a direct association of WC (quartile distribution) and BMI categories with ox-LDL (P for linear trend = 0.002) and CRP (P for linear trend = 0.004). Subjects in the top quartile of WC and with a BMI > 29.9 were at high...
language: eng
source:
identifier: ISSN: 0002-9165
fulltext: fulltext
issn:
  • 00029165
  • 0002-9165
url: Link


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titleCirculating oxidized LDL is associated with increased waist circumference independent of body mass index in men and women.
creatorWeinbrenner, Tanja ; Schröder, Helmut ; Escurriol, Veronica ; Fito, Montserrat ; Elosua, Roberto ; Vila, Joan ; Marrugat, Jaume ; Covas, Maria-Isabel
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ispartofThe American journal of clinical nutrition, January 2006, Vol.83(1), pp.30-5; quiz 181-2
identifierISSN: 0002-9165
subjectAbdominal Fat–Metabolism ; Adult–Metabolism ; Aged–Etiology ; Body Mass Index–Metabolism ; C-Reactive Protein–Blood ; Cardiovascular Diseases–Metabolism ; Cross-Sectional Studies–Etiology ; Female–Metabolism ; Humans–Blood ; Linear Models–Complications ; Lipoproteins, LDL–Metabolism ; Logistic Models–Physiology ; Male–Physiology ; Metabolic Syndrome–Physiology ; Middle Aged–Physiology ; Multivariate Analysis–Physiology ; Obesity–Physiology ; Oxidation-Reduction–Physiology ; Oxidative Stress–Physiology ; Risk Factors
descriptionBACKGROUNDObesity is associated with oxidative stress, and the oxidation of LDL is thought to play a crucial role in the generation of atherosclerotic lesions. OBJECTIVEThe objective was to describe the association of waist circumference (WC) and body mass index (BMI; in kg/m2) with plasma circulating oxidized LDL (ox-LDL) and C-reactive protein (CRP). DESIGNThis cross-sectional study included data for circulating ox-LDL and CRP from a subpopulation of 586 men and women enrolled in a population-based survey conducted in 2000 in Girona, Spain. Multivariate analysis was performed to describe the independent association of WC and BMI with ox-LDL and CRP. RESULTSMultivariate logistic regression analysis adjusted for lifestyle, educational level, and dietary confounders showed a direct association of WC (quartile distribution) and BMI categories with ox-LDL (P for linear trend = 0.002) and CRP (P for linear trend = 0.004). Subjects in the top quartile of WC and with a BMI > 29.9 were at high...
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titleCirculating oxidized LDL is associated with increased waist circumference independent of body mass index in men and women.
descriptionBACKGROUNDObesity is associated with oxidative stress, and the oxidation of LDL is thought to play a crucial role in the generation of atherosclerotic lesions. OBJECTIVEThe objective was to describe the association of waist circumference (WC) and body mass index (BMI; in kg/m2) with plasma circulating oxidized LDL (ox-LDL) and C-reactive protein (CRP). DESIGNThis cross-sectional study included data for circulating ox-LDL and CRP from a subpopulation of 586 men and women enrolled in a population-based survey conducted in 2000 in Girona, Spain. Multivariate analysis was performed to describe the independent association of WC and BMI with ox-LDL and CRP. RESULTSMultivariate logistic regression analysis adjusted for lifestyle, educational level, and dietary confounders showed a direct association of WC (quartile distribution) and BMI categories with ox-LDL (P for linear trend = 0.002) and CRP (P for linear trend = 0.004). Subjects in the top quartile of WC and with a BMI > 29.9 were at high...
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titleCirculating oxidized LDL is associated with increased waist circumference independent of body mass index in men and women.
authorWeinbrenner, Tanja ; Schröder, Helmut ; Escurriol, Veronica ; Fito, Montserrat ; Elosua, Roberto ; Vila, Joan ; Marrugat, Jaume ; Covas, Maria-Isabel
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abstractBACKGROUNDObesity is associated with oxidative stress, and the oxidation of LDL is thought to play a crucial role in the generation of atherosclerotic lesions. OBJECTIVEThe objective was to describe the association of waist circumference (WC) and body mass index (BMI; in kg/m2) with plasma circulating oxidized LDL (ox-LDL) and C-reactive protein (CRP). DESIGNThis cross-sectional study included data for circulating ox-LDL and CRP from a subpopulation of 586 men and women enrolled in a population-based survey conducted in 2000 in Girona, Spain. Multivariate analysis was performed to describe the independent association of WC and BMI with ox-LDL and CRP. RESULTSMultivariate logistic regression analysis adjusted for lifestyle, educational level, and dietary confounders showed a direct association of WC (quartile distribution) and BMI categories with ox-LDL (P for linear trend = 0.002) and CRP (P for linear trend = 0.004). Subjects in the top quartile of WC and with a BMI > 29.9 were at high...
urlhttp://search.proquest.com/docview/67610452/
doi10.1093/ajcn/83.1.30
eissn19383207
date2006-01-01