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How an increased intake of alpha-tocopherol can suppress the bioavailability of gamma-tocopherol.

[alpha]-Tocopherol is the only form of vitamin E in vitamin supplements, whereas [gamma]-tocopherol is the predominant form of vitamin E in the US diet. [gamma]-Tocopherol has beneficial properties as an anti-inflammatory and possibly anti-atherogenic and anticancer agent. Excess [alpha]-tocopherol... Full description

Journal Title: Nutrition reviews Vol.64(6), pp.295-299
Main Author: Wolf, George
Format: Electronic Article Electronic Article
Language: English
Subjects:
Created: June 2006
ID: ISSN: 0029-6643
Link: http://search.proquest.com/docview/68591167/?pq-origsite=primo
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recordid: proquest68591167
title: How an increased intake of alpha-tocopherol can suppress the bioavailability of gamma-tocopherol.
format: Article
creator:
  • Wolf, George
subjects:
  • Biological Availability–Pharmacokinetics
  • Diet–Pharmacology
  • Dietary Supplements–Pharmacology
  • Humans–Blood
  • Vitamins–Pharmacokinetics
  • Alpha-Tocopherol–Pharmacokinetics
  • Gamma-Tocopherol–Pharmacokinetics
  • Vitamins
  • Gamma-Tocopherol
  • Alpha-Tocopherol
ispartof: Nutrition reviews, Vol.64(6), pp.295-299
description: [alpha]-Tocopherol is the only form of vitamin E in vitamin supplements, whereas [gamma]-tocopherol is the predominant form of vitamin E in the US diet. [gamma]-Tocopherol has beneficial properties as an anti-inflammatory and possibly anti-atherogenic and anticancer agent. Excess [alpha]-tocopherol taken in supplements causes a reduction of [gamma]-tocopherol concentration in plasma. The biochemical mechanism of this effect, which is important to human nutrition, has recently been elucidated. Key words: [alpha]-tocopherol; [alpha]-tocopherol transfer protein; antioxidant; anti-inflammatory; [alpha]-carboxyethyl-hydroxychroman ([alpha]CEHC); [alpha]-carboxyethyl-hydroxychroman ([gamma]CEHC), [gamma]-tocopherol; vitamin E
language: eng
source:
identifier: ISSN: 0029-6643
fulltext: fulltext
issn:
  • 00296643
  • 0029-6643
url: Link


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titleHow an increased intake of alpha-tocopherol can suppress the bioavailability of gamma-tocopherol.
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ispartofNutrition reviews, Vol.64(6), pp.295-299
identifierISSN: 0029-6643
subjectBiological Availability–Pharmacokinetics ; Diet–Pharmacology ; Dietary Supplements–Pharmacology ; Humans–Blood ; Vitamins–Pharmacokinetics ; Alpha-Tocopherol–Pharmacokinetics ; Gamma-Tocopherol–Pharmacokinetics ; Vitamins ; Gamma-Tocopherol ; Alpha-Tocopherol
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description[alpha]-Tocopherol is the only form of vitamin E in vitamin supplements, whereas [gamma]-tocopherol is the predominant form of vitamin E in the US diet. [gamma]-Tocopherol has beneficial properties as an anti-inflammatory and possibly anti-atherogenic and anticancer agent. Excess [alpha]-tocopherol taken in supplements causes a reduction of [gamma]-tocopherol concentration in plasma. The biochemical mechanism of this effect, which is important to human nutrition, has recently been elucidated. Key words: [alpha]-tocopherol; [alpha]-tocopherol transfer protein; antioxidant; anti-inflammatory; [alpha]-carboxyethyl-hydroxychroman ([alpha]CEHC); [alpha]-carboxyethyl-hydroxychroman ([gamma]CEHC), [gamma]-tocopherol; vitamin E
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