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The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group.

BACKGROUNDCardiovascular complications are the most important causes of perioperative morbidity and mortality among patients undergoing major vascular surgery. METHODSWe performed a randomized, multicenter trial to assess the effect of perioperative blockade of beta-adrenergic receptors on the incid... Full description

Journal Title: The New England journal of medicine December 9, 1999, Vol.341(24), pp.1789-1794
Main Author: Poldermans, D
Other Authors: Boersma, E , Bax, J J , Thomson, I R , van de Ven, L L , Blankensteijn, J D , Baars, H F , Yo, T I , Trocino, G , Vigna, C , Roelandt, J R , van Urk, H
Format: Electronic Article Electronic Article
Language: English
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ID: ISSN: 0028-4793
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title: The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group.
format: Article
creator:
  • Poldermans, D
  • Boersma, E
  • Bax, J J
  • Thomson, I R
  • van de Ven, L L
  • Blankensteijn, J D
  • Baars, H F
  • Yo, T I
  • Trocino, G
  • Vigna, C
  • Roelandt, J R
  • van Urk, H
subjects:
  • Adrenergic Beta-Antagonists–Pharmacology
  • Aged–Therapeutic Use
  • Bisoprolol–Pharmacology
  • Female–Therapeutic Use
  • Heart Diseases–Mortality
  • Heart Rate–Prevention & Control
  • Humans–Drug Effects
  • Incidence–Epidemiology
  • Male–Prevention & Control
  • Middle Aged–Diagnostic Imaging
  • Myocardial Infarction–Epidemiology
  • Myocardial Ischemia–Mortality
  • Perioperative Care–Prevention & Control
  • Postoperative Complications–Prevention & Control
  • Risk Factors–Prevention & Control
ispartof: The New England journal of medicine, December 9, 1999, Vol.341(24), pp.1789-1794
description: BACKGROUNDCardiovascular complications are the most important causes of perioperative morbidity and mortality among patients undergoing major vascular surgery. METHODSWe performed a randomized, multicenter trial to assess the effect of perioperative blockade of beta-adrenergic receptors on the incidence of death from cardiac causes and nonfatal myocardial infarction within 30 days after major vascular surgery in patients at high risk for these events. High-risk patients were identified by the presence of both clinical risk factors and positive results on dobutamine echocardiography. Eligible patients were randomly assigned to receive standard perioperative care or standard care plus perioperative beta-blockade with bisoprolol. RESULTSA total of 1351 patients were screened, and 846 were found to have one or more cardiac risk factors. Of these 846 patients, 173 had positive results on dobutamine echocardiography. Fifty-nine patients were randomly assigned to receive bisoprolol, and 53 to...
language: eng
source:
identifier: ISSN: 0028-4793
fulltext: fulltext
issn:
  • 00284793
  • 0028-4793
url: Link


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titleThe effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group.
creatorPoldermans, D ; Boersma, E ; Bax, J J ; Thomson, I R ; van de Ven, L L ; Blankensteijn, J D ; Baars, H F ; Yo, T I ; Trocino, G ; Vigna, C ; Roelandt, J R ; van Urk, H
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ispartofThe New England journal of medicine, December 9, 1999, Vol.341(24), pp.1789-1794
identifierISSN: 0028-4793
subjectAdrenergic Beta-Antagonists–Pharmacology ; Aged–Therapeutic Use ; Bisoprolol–Pharmacology ; Female–Therapeutic Use ; Heart Diseases–Mortality ; Heart Rate–Prevention & Control ; Humans–Drug Effects ; Incidence–Epidemiology ; Male–Prevention & Control ; Middle Aged–Diagnostic Imaging ; Myocardial Infarction–Epidemiology ; Myocardial Ischemia–Mortality ; Perioperative Care–Prevention & Control ; Postoperative Complications–Prevention & Control ; Risk Factors–Prevention & Control
descriptionBACKGROUNDCardiovascular complications are the most important causes of perioperative morbidity and mortality among patients undergoing major vascular surgery. METHODSWe performed a randomized, multicenter trial to assess the effect of perioperative blockade of beta-adrenergic receptors on the incidence of death from cardiac causes and nonfatal myocardial infarction within 30 days after major vascular surgery in patients at high risk for these events. High-risk patients were identified by the presence of both clinical risk factors and positive results on dobutamine echocardiography. Eligible patients were randomly assigned to receive standard perioperative care or standard care plus perioperative beta-blockade with bisoprolol. RESULTSA total of 1351 patients were screened, and 846 were found to have one or more cardiac risk factors. Of these 846 patients, 173 had positive results on dobutamine echocardiography. Fifty-nine patients were randomly assigned to receive bisoprolol, and 53 to...
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titleThe effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group.
descriptionBACKGROUNDCardiovascular complications are the most important causes of perioperative morbidity and mortality among patients undergoing major vascular surgery. METHODSWe performed a randomized, multicenter trial to assess the effect of perioperative blockade of beta-adrenergic receptors on the incidence of death from cardiac causes and nonfatal myocardial infarction within 30 days after major vascular surgery in patients at high risk for these events. High-risk patients were identified by the presence of both clinical risk factors and positive results on dobutamine echocardiography. Eligible patients were randomly assigned to receive standard perioperative care or standard care plus perioperative beta-blockade with bisoprolol. RESULTSA total of 1351 patients were screened, and 846 were found to have one or more cardiac risk factors. Of these 846 patients, 173 had positive results on dobutamine echocardiography. Fifty-nine patients were randomly assigned to receive bisoprolol, and 53 to...
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titleThe effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group.
authorPoldermans, D ; Boersma, E ; Bax, J J ; Thomson, I R ; van de Ven, L L ; Blankensteijn, J D ; Baars, H F ; Yo, T I ; Trocino, G ; Vigna, C ; Roelandt, J R ; van Urk, H
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abstractBACKGROUNDCardiovascular complications are the most important causes of perioperative morbidity and mortality among patients undergoing major vascular surgery. METHODSWe performed a randomized, multicenter trial to assess the effect of perioperative blockade of beta-adrenergic receptors on the incidence of death from cardiac causes and nonfatal myocardial infarction within 30 days after major vascular surgery in patients at high risk for these events. High-risk patients were identified by the presence of both clinical risk factors and positive results on dobutamine echocardiography. Eligible patients were randomly assigned to receive standard perioperative care or standard care plus perioperative beta-blockade with bisoprolol. RESULTSA total of 1351 patients were screened, and 846 were found to have one or more cardiac risk factors. Of these 846 patients, 173 had positive results on dobutamine echocardiography. Fifty-nine patients were randomly assigned to receive bisoprolol, and 53 to...
urlhttp://search.proquest.com/docview/69339555/
doi10.1056/NEJM199912093412402
eissn15334406
date1999-12-09