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Effect of diet on mucin kinetics and composition: nutrition and health implications.

The mucus gel covering the gut epithelium is in dynamic balance between synthesis and secretion of mucin from goblet cells and proteolytic and physical erosion that releases mucin into the lumen. In the lumen, mucin is partially protected from proteolysis by carbohydrate chains, and it contributes t... Full description

Journal Title: Nutrition reviews Vol.62(3), pp.105-114
Main Author: Montagne, L
Other Authors: Piel, C , Lallès, J P
Format: Electronic Article Electronic Article
Language: English
Subjects:
Created: March 2004
ID: ISSN: 0029-6643
Link: http://search.proquest.com/docview/71860800/?pq-origsite=primo
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title: Effect of diet on mucin kinetics and composition: nutrition and health implications.
format: Article
creator:
  • Montagne, L
  • Piel, C
  • Lallès, J P
subjects:
  • Animal Nutritional Physiological Phenomena–Microbiology
  • Animals–Metabolism
  • Diet–Physiology
  • Digestive System–Metabolism
  • Digestive System Physiological Phenomena–Physiology
  • Humans–Secretion
  • Intestinal Mucosa–Metabolism
  • Mucins–Metabolism
  • Mucus–Metabolism
  • Proteins–Metabolism
  • Mucins
  • Proteins
ispartof: Nutrition reviews, Vol.62(3), pp.105-114
description: The mucus gel covering the gut epithelium is in dynamic balance between synthesis and secretion of mucin from goblet cells and proteolytic and physical erosion that releases mucin into the lumen. In the lumen, mucin is partially protected from proteolysis by carbohydrate chains, and it contributes to endogenous protein reaching the ileum. Dietary components modulate the contribution of mucin to endogenous protein components and their qualitative composition. In addition, mucin plays a key role in gastrointestinal protection in association with the microflora. In this review, we will attempt to evaluate the consequences of dietary manipulation of mucin on gut health. [PUBLICATION ] Key words: mucus, mucin, endogenous losses, digestion, protein
language: eng
source:
identifier: ISSN: 0029-6643
fulltext: fulltext
issn:
  • 00296643
  • 0029-6643
url: Link


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titleEffect of diet on mucin kinetics and composition: nutrition and health implications.
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ispartofNutrition reviews, Vol.62(3), pp.105-114
identifierISSN: 0029-6643
subjectAnimal Nutritional Physiological Phenomena–Microbiology ; Animals–Metabolism ; Diet–Physiology ; Digestive System–Metabolism ; Digestive System Physiological Phenomena–Physiology ; Humans–Secretion ; Intestinal Mucosa–Metabolism ; Mucins–Metabolism ; Mucus–Metabolism ; Proteins–Metabolism ; Mucins ; Proteins
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descriptionThe mucus gel covering the gut epithelium is in dynamic balance between synthesis and secretion of mucin from goblet cells and proteolytic and physical erosion that releases mucin into the lumen. In the lumen, mucin is partially protected from proteolysis by carbohydrate chains, and it contributes to endogenous protein reaching the ileum. Dietary components modulate the contribution of mucin to endogenous protein components and their qualitative composition. In addition, mucin plays a key role in gastrointestinal protection in association with the microflora. In this review, we will attempt to evaluate the consequences of dietary manipulation of mucin on gut health. [PUBLICATION ] Key words: mucus, mucin, endogenous losses, digestion, protein
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