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Metabolic control of gluconeogenesis in transgenic mice: regulation of the phosphoenolpyruvate carboxykinase gene.

Diet and the effect of hormones were studied in transgenic mice bearing a part of the promoter of the gene for the gluconeogenic enzyme phosphoenolpyruvate carboxykinase. The domains of the gene promoter involved in tissue specificity, development, and response to diet were identified by analysis of... Full description

Journal Title: Nutrition reviews Vol.52(8 Pt 1), pp.275-277
Main Author: Wolf, G
Format: Electronic Article Electronic Article
Language: English
Subjects:
Created: August 1994
ID: ISSN: 0029-6643
Link: http://search.proquest.com/docview/76835862/?pq-origsite=primo
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recordid: proquest76835862
title: Metabolic control of gluconeogenesis in transgenic mice: regulation of the phosphoenolpyruvate carboxykinase gene.
format: Article
creator:
  • Wolf, G
subjects:
  • Animals–Physiology
  • Cyclic Amp–Genetics
  • Diet–Genetics
  • Gene Expression Regulation–Genetics
  • Gluconeogenesis–Genetics
  • Growth–Genetics
  • Mice–Genetics
  • Mice, Transgenic–Genetics
  • Organ Specificity–Genetics
  • Phosphoenolpyruvate Carboxykinase (Gtp)–Genetics
  • Cyclic Amp
  • Phosphoenolpyruvate Carboxykinase (Gtp)
ispartof: Nutrition reviews, Vol.52(8 Pt 1), pp.275-277
description: Diet and the effect of hormones were studied in transgenic mice bearing a part of the promoter of the gene for the gluconeogenic enzyme phosphoenolpyruvate carboxykinase. The domains of the gene promoter involved in tissue specificity, development, and response to diet were identified by analysis of expression of the mutated gene. Important differences were uncovered between results from earlier cell culture experiments and the results from more physiologic responses of the transgenic animals.
language: eng
source:
identifier: ISSN: 0029-6643
fulltext: fulltext
issn:
  • 00296643
  • 0029-6643
url: Link


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titleMetabolic control of gluconeogenesis in transgenic mice: regulation of the phosphoenolpyruvate carboxykinase gene.
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ispartofNutrition reviews, Vol.52(8 Pt 1), pp.275-277
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subjectAnimals–Physiology ; Cyclic Amp–Genetics ; Diet–Genetics ; Gene Expression Regulation–Genetics ; Gluconeogenesis–Genetics ; Growth–Genetics ; Mice–Genetics ; Mice, Transgenic–Genetics ; Organ Specificity–Genetics ; Phosphoenolpyruvate Carboxykinase (Gtp)–Genetics ; Cyclic Amp ; Phosphoenolpyruvate Carboxykinase (Gtp)
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descriptionDiet and the effect of hormones were studied in transgenic mice bearing a part of the promoter of the gene for the gluconeogenic enzyme phosphoenolpyruvate carboxykinase. The domains of the gene promoter involved in tissue specificity, development, and response to diet were identified by analysis of expression of the mutated gene. Important differences were uncovered between results from earlier cell culture experiments and the results from more physiologic responses of the transgenic animals.
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