schliessen

Filtern

 

Bibliotheken

Detection of plasmid-mediated IMP-1 metallo-[beta]-lactamase and quinolone resistance determinants in an ertapenem-resistant Enterobacter cloacae isolate

To investigate the mechanism of carbapenem resistance and the occurrence of plasmid-mediated quinolone resistance determinants qnr and aac(6')-Ib-cr in a clinical isolate of Enterobacter cloacae. An ertapenem-resistant E. cloacae ZY106, which was isolated from liquor puris of a female gastric cancer... Full description

Journal Title: Journal of Zhejiang University May 2009, Vol.10(5), pp.348-54
Main Author: Chen, Li-Rong
Other Authors: Zhou, Hong-Wei , Cai, Jia-Chang , Zhang, Rong , Chen, Gong-Xiang
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 16731581 ; E-ISSN: 18621783 ; DOI: 10.1631/jzus.B0820302
Link: http://search.proquest.com/docview/883383072/?pq-origsite=primo
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: proquest883383072
title: Detection of plasmid-mediated IMP-1 metallo-[beta]-lactamase and quinolone resistance determinants in an ertapenem-resistant Enterobacter cloacae isolate
format: Article
creator:
  • Chen, Li-Rong
  • Zhou, Hong-Wei
  • Cai, Jia-Chang
  • Zhang, Rong
  • Chen, Gong-Xiang
subjects:
  • Enterobacter Cloacae–Drug Effects
  • Enterobacter Cloacae–Enzymology
  • Enterobacter Cloacae–Genetics
  • Plasmids–Genetics
  • Quinolones–Administration & Dosage
  • Beta-Lactamases–Genetics
  • Beta-Lactamases–Metabolism
  • Beta-Lactams–Administration & Dosage
  • Bacteria
  • Plasmids
  • Studies
  • E Coli
  • Experimental/Theoretical
  • Quinolones
  • Beta-Lactams
  • Beta-Lactamase IMP-1
  • Beta-Lactamases
  • Ertapenem
ispartof: Journal of Zhejiang University, May 2009, Vol.10(5), pp.348-54
description: To investigate the mechanism of carbapenem resistance and the occurrence of plasmid-mediated quinolone resistance determinants qnr and aac(6')-Ib-cr in a clinical isolate of Enterobacter cloacae. An ertapenem-resistant E. cloacae ZY106, which was isolated from liquor puris of a female gastric cancer patient in a Chinese hospital, was investigated. Antibiotic susceptibilities were determined by agar dilution method. Conjugation experiments, isoelectric focusing, polymerase chain reaction (PCR), and DNA sequence analyses of plasmid-mediated carbapenemases and quinolone resistance determinants were preformed to confirm the genotype. Outer membrane proteins (OMPs) were examined by urea-sodium dodecyl sulfatepolyacrylamide gel electrophoresis (Urea-SDS-PAGE). Minimum inhibitory concentrations (MICs) of imipenem, meropenem, and ertapenem for ZY106 were 2, 4, and 16 μg/ml, respectively. Conjugation studies with Escherichia coli resulted in the transfer of significantly reduced carbapenem susceptibility....
language: eng
source:
identifier: ISSN: 16731581 ; E-ISSN: 18621783 ; DOI: 10.1631/jzus.B0820302
fulltext: fulltext
issn:
  • 16731581
  • 1673-1581
  • 18621783
  • 1862-1783
url: Link


@attributes
ID617296330
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid883383072
sourceidproquest
recordidTN_proquest883383072
sourcesystemPC
pqid883383072
galeid228100818
display
typearticle
titleDetection of plasmid-mediated IMP-1 metallo-[beta]-lactamase and quinolone resistance determinants in an ertapenem-resistant Enterobacter cloacae isolate
creatorChen, Li-Rong ; Zhou, Hong-Wei ; Cai, Jia-Chang ; Zhang, Rong ; Chen, Gong-Xiang
ispartofJournal of Zhejiang University, May 2009, Vol.10(5), pp.348-54
identifier
subjectEnterobacter Cloacae–Drug Effects ; Enterobacter Cloacae–Enzymology ; Enterobacter Cloacae–Genetics ; Plasmids–Genetics ; Quinolones–Administration & Dosage ; Beta-Lactamases–Genetics ; Beta-Lactamases–Metabolism ; Beta-Lactams–Administration & Dosage ; Bacteria ; Plasmids ; Studies ; E Coli ; Experimental/Theoretical ; Quinolones ; Beta-Lactams ; Beta-Lactamase IMP-1 ; Beta-Lactamases ; Ertapenem
descriptionTo investigate the mechanism of carbapenem resistance and the occurrence of plasmid-mediated quinolone resistance determinants qnr and aac(6')-Ib-cr in a clinical isolate of Enterobacter cloacae. An ertapenem-resistant E. cloacae ZY106, which was isolated from liquor puris of a female gastric cancer patient in a Chinese hospital, was investigated. Antibiotic susceptibilities were determined by agar dilution method. Conjugation experiments, isoelectric focusing, polymerase chain reaction (PCR), and DNA sequence analyses of plasmid-mediated carbapenemases and quinolone resistance determinants were preformed to confirm the genotype. Outer membrane proteins (OMPs) were examined by urea-sodium dodecyl sulfatepolyacrylamide gel electrophoresis (Urea-SDS-PAGE). Minimum inhibitory concentrations (MICs) of imipenem, meropenem, and ertapenem for ZY106 were 2, 4, and 16 μg/ml, respectively. Conjugation studies with Escherichia coli resulted in the transfer of significantly reduced carbapenem susceptibility....
languageeng
source
version9
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
backlink$$Uhttp://search.proquest.com/docview/883383072/?pq-origsite=primo$$EView_record_in_ProQuest_(subscribers_only)
search
creatorcontrib
0Chen, Li-Rong
1Zhou, Hong-Wei
2Cai, Jia-Chang
3Zhang, Rong
4Chen, Gong-Xiang
titleDetection of plasmid-mediated IMP-1 metallo-[beta]-lactamase and quinolone resistance determinants in an ertapenem-resistant Enterobacter cloacae isolate
descriptionTo investigate the mechanism of carbapenem resistance and the occurrence of plasmid-mediated quinolone resistance determinants qnr and aac(6')-Ib-cr in a clinical isolate of Enterobacter cloacae. An ertapenem-resistant E. cloacae ZY106, which was isolated from liquor puris of a female gastric cancer patient in a Chinese hospital, was investigated. Antibiotic susceptibilities were determined by agar dilution method. Conjugation experiments, isoelectric focusing, polymerase chain reaction (PCR), and DNA sequence analyses of plasmid-mediated carbapenemases and quinolone resistance determinants were preformed to confirm the genotype. Outer membrane proteins (OMPs) were examined by urea-sodium dodecyl sulfatepolyacrylamide gel electrophoresis (Urea-SDS-PAGE). Minimum inhibitory concentrations (MICs) of imipenem, meropenem, and ertapenem for ZY106 were 2, 4, and 16 μg/ml, respectively. Conjugation studies with Escherichia coli resulted in the transfer of significantly reduced carbapenem susceptibility....
subject
0Enterobacter Cloacae–Drug Effects
1Enterobacter Cloacae–Enzymology
2Enterobacter Cloacae–Genetics
3Plasmids–Genetics
4Quinolones–Administration & Dosage
5Beta-Lactamases–Genetics
6Beta-Lactamases–Metabolism
7Beta-Lactams–Administration & Dosage
8Bacteria
9Plasmids
10Studies
11E Coli
12Experimental/Theoretical
13Quinolones
14Beta-Lactams
15Beta-Lactamase IMP-1
16Beta-Lactamases
17Ertapenem
189130
general
0English
1Springer Nature B.V.
210.1631/jzus.B0820302
3Medical Database
4Health & Medical Collection (Alumni edition)
5Medical Database (Alumni edition)
6ProQuest Pharma Collection
7Health & Medical Collection
8ProQuest Agriculture Journals
9Neurosciences Abstracts
10Aquatic Science Journals
11Materials Science Database
12Advanced Technologies & Aerospace Database
13Engineering Database
14Biological Science Database
15Environmental Science Database (ProQuest)
16Earth, Atmospheric & Aquatic Science Database (ProQuest)
17Engineering Research Database
18Technology Research Database
19ProQuest Agricultural Science Collection
20ProQuest Aquatic Science Collection
21ProQuest Atmospheric Science Collection
22ProQuest Biological Science Collection
23ProQuest Central
24ProQuest Earth Science Collection
25ProQuest Engineering Collection
26ProQuest Environmental Science Collection
27ProQuest Advanced Technologies & Aerospace Collection
28ProQuest Hospital Collection
29ProQuest Materials Science Collection
30ProQuest Natural Science Collection
31ProQuest Technology Collection
32Hospital Premium Collection (Alumni edition)
33ProQuest SciTech Collection
34ProQuest Health & Medical Complete
35ProQuest Medical Library
36Agricultural & Environmental Science Database
37Earth, Atmospheric & Aquatic Science Database
38Materials Science & Engineering Database
39Natural Science Collection
40ProQuest Central (new)
41ProQuest Central K-12
42ProQuest Central Korea
43SciTech Premium Collection
44Technology Collection
45Health Research Premium Collection
46Health Research Premium Collection (Alumni edition)
47ProQuest Central Essentials
48ProQuest Central China
49ProQuest One Academic
50Environmental Science Index (ProQuest)
51Biological Science Index (ProQuest)
52Engineering Index (ProQuest)
53Environmental Science Collection (ProQuest)
54Materials Science Collection (ProQuest)
55Engineering Collection (ProQuest)
sourceidproquest
recordidproquest883383072
issn
016731581
11673-1581
218621783
31862-1783
rsrctypearticle
creationdate2009
addtitleJournal of Zhejiang University
searchscope
01000273
11006072
21006761
31006762
41006815
51007067
61007160
71007443
81007444
91007536
101007844
111007845
121007849
131007851
141007852
151007853
161007856
171007945
181008886
191009127
201009386
211009714
221009715
2310000004
2410000005
2510000013
2610000015
2710000022
2810000035
2910000036
3010000037
3110000038
3210000039
3310000040
3410000041
3510000043
3610000045
3710000047
3810000049
3910000050
4010000053
4110000118
4210000119
4310000120
4410000155
4510000156
4610000157
4710000158
4810000198
4910000209
5010000217
5110000233
5210000234
5310000238
5410000244
5510000250
5610000253
5710000255
5810000256
5910000257
6010000258
6110000260
6210000265
6310000268
6410000270
6510000271
6610000281
6710000300
6810000302
6910000348
7010000349
7110000350
7210000353
7310000354
7410000355
7510000356
7610000360
77proquest
scope
01000273
11006072
21006761
31006762
41006815
51007067
61007160
71007443
81007444
91007536
101007844
111007845
121007849
131007851
141007852
151007853
161007856
171007945
181008886
191009127
201009386
211009714
221009715
2310000004
2410000005
2510000013
2610000015
2710000022
2810000035
2910000036
3010000037
3110000038
3210000039
3310000040
3410000041
3510000043
3610000045
3710000047
3810000049
3910000050
4010000053
4110000118
4210000119
4310000120
4410000155
4510000156
4610000157
4710000158
4810000198
4910000209
5010000217
5110000233
5210000234
5310000238
5410000244
5510000250
5610000253
5710000255
5810000256
5910000257
6010000258
6110000260
6210000265
6310000268
6410000270
6510000271
6610000281
6710000300
6810000302
6910000348
7010000349
7110000350
7210000353
7310000354
7410000355
7510000356
7610000360
77proquest
lsr43
01000273true
11006072true
21006761true
31006762true
41006815true
51007067true
61007160true
71007443false
81007444false
91007536false
101007844true
111007845true
121007849true
131007851true
141007852true
151007853true
161007856true
171007945true
181008886true
191009127true
201009386true
211009714true
221009715true
2310000004false
2410000005false
2510000013false
2610000015false
2710000022false
2810000035true
2910000036true
3010000037true
3110000038true
3210000039true
3310000040true
3410000041true
3510000043true
3610000045true
3710000047true
3810000049true
3910000050true
4010000053true
4110000118true
4210000119true
4310000120true
4410000155true
4510000156true
4610000157true
4710000158true
4810000198false
4910000209false
5010000217false
5110000233true
5210000234true
5310000238true
5410000244true
5510000250true
5610000253true
5710000255true
5810000256true
5910000257true
6010000258true
6110000260true
6210000265true
6310000268true
6410000270true
6510000271true
6610000281true
6710000300true
6810000302true
6910000348true
7010000349false
7110000350false
7210000353false
7310000354true
7410000355true
7510000356true
7610000360true
startdate20090501
enddate20090501
citationpf 348 pt 54 vol 10 issue 5
lsr30VSR-Enriched:[galeid, pages, pqid]
sort
titleDetection of plasmid-mediated IMP-1 metallo-[beta]-lactamase and quinolone resistance determinants in an ertapenem-resistant Enterobacter cloacae isolate
authorChen, Li-Rong ; Zhou, Hong-Wei ; Cai, Jia-Chang ; Zhang, Rong ; Chen, Gong-Xiang
creationdate20090501
lso0120090501
facets
frbrgroupid9194328697906271888
frbrtype5
languageeng
creationdate2009
topic
0Enterobacter Cloacae–Drug Effects
1Enterobacter Cloacae–Enzymology
2Enterobacter Cloacae–Genetics
3Plasmids–Genetics
4Quinolones–Administration & Dosage
5Beta-Lactamases–Genetics
6Beta-Lactamases–Metabolism
7Beta-Lactams–Administration & Dosage
8Bacteria
9Plasmids
10Studies
11E Coli
12Experimental/Theoretical
13Quinolones
14Beta-Lactams
15Beta-Lactamase IMP-1
16Beta-Lactamases
17Ertapenem
collection
0Medical Database
1Health & Medical Collection (Alumni edition)
2Medical Database (Alumni edition)
3ProQuest Pharma Collection
4Health & Medical Collection
5ProQuest Agriculture Journals
6Neurosciences Abstracts
7Aquatic Science Journals
8Materials Science Database
9Advanced Technologies & Aerospace Database
10Engineering Database
11Biological Science Database
12Environmental Science Database (ProQuest)
13Earth, Atmospheric & Aquatic Science Database (ProQuest)
14Engineering Research Database
15Technology Research Database
16ProQuest Agricultural Science Collection
17ProQuest Aquatic Science Collection
18ProQuest Atmospheric Science Collection
19ProQuest Biological Science Collection
20ProQuest Central
21ProQuest Earth Science Collection
22ProQuest Engineering Collection
23ProQuest Environmental Science Collection
24ProQuest Advanced Technologies & Aerospace Collection
25ProQuest Hospital Collection
26ProQuest Materials Science Collection
27ProQuest Natural Science Collection
28ProQuest Technology Collection
29Hospital Premium Collection (Alumni edition)
30ProQuest SciTech Collection
31ProQuest Health & Medical Complete
32ProQuest Medical Library
33Agricultural & Environmental Science Database
34Earth, Atmospheric & Aquatic Science Database
35Materials Science & Engineering Database
36Natural Science Collection
37ProQuest Central (new)
38ProQuest Central K-12
39ProQuest Central Korea
40SciTech Premium Collection
41Technology Collection
42Health Research Premium Collection
43Health Research Premium Collection (Alumni edition)
44ProQuest Central Essentials
45ProQuest Central China
46ProQuest One Academic
47Environmental Science Index (ProQuest)
48Biological Science Index (ProQuest)
49Engineering Index (ProQuest)
50Environmental Science Collection (ProQuest)
51Materials Science Collection (ProQuest)
52Engineering Collection (ProQuest)
prefilterarticles
rsrctypearticles
creatorcontrib
0Chen, Li-Rong
1Zhou, Hong-Wei
2Cai, Jia-Chang
3Zhang, Rong
4Chen, Gong-Xiang
jtitleJournal of Zhejiang University
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Chen
1Zhou
2Cai
3Zhang
aufirst
0Li-rong
1Hong-wei
2Jia-chang
3Rong
4Gong-xiang
auinit1
0L.
1H.
2J.
3R.
4G.
au
0Chen, Li-Rong
1Zhou, Hong-Wei
2Cai, Jia-Chang
3Zhang, Rong
4Chen, Gong-Xiang
atitleDetection of plasmid-mediated IMP-1 metallo-[beta]-lactamase and quinolone resistance determinants in an ertapenem-resistant Enterobacter cloacae isolate
jtitleJournal of Zhejiang University
risdate20090501
volume10
issue5
spage348
epage54
pages348-354
issn16731581
eissn18621783
formatjournal
genrearticle
ristypeJOUR
abstractTo investigate the mechanism of carbapenem resistance and the occurrence of plasmid-mediated quinolone resistance determinants qnr and aac(6')-Ib-cr in a clinical isolate of Enterobacter cloacae. An ertapenem-resistant E. cloacae ZY106, which was isolated from liquor puris of a female gastric cancer patient in a Chinese hospital, was investigated. Antibiotic susceptibilities were determined by agar dilution method. Conjugation experiments, isoelectric focusing, polymerase chain reaction (PCR), and DNA sequence analyses of plasmid-mediated carbapenemases and quinolone resistance determinants were preformed to confirm the genotype. Outer membrane proteins (OMPs) were examined by urea-sodium dodecyl sulfatepolyacrylamide gel electrophoresis (Urea-SDS-PAGE). Minimum inhibitory concentrations (MICs) of imipenem, meropenem, and ertapenem for ZY106 were 2, 4, and 16 μg/ml, respectively. Conjugation studies with Escherichia coli resulted in the transfer of significantly reduced carbapenem susceptibility....
copHangzhou
pubSpringer Nature B.V.
doi10.1631/jzus.B0820302
urlhttp://search.proquest.com/docview/883383072/
date2009-05-01