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Cross-coupling in flow.

Until recently, cross-coupling reactions have been exclusively performed in batch processes. With the advent of microfluidics, significant effort has been devoted to develop a wide variety of continuous-flow techniques to facilitate organic synthesis. In this critical review, we attempt to give an o... Full description

Journal Title: Chemical Society reviews October 2011, Vol.40(10), pp.5010-5029
Main Author: Noël, Timothy
Other Authors: Buchwald, Stephen L
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1460-4744 ; DOI: 10.1039/c1cs15075h
Link: http://search.proquest.com/docview/893277122/?pq-origsite=primo
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recordid: proquest893277122
title: Cross-coupling in flow.
format: Article
creator:
  • Noël, Timothy
  • Buchwald, Stephen L
subjects:
  • Carbon–Chemistry
  • Chemistry, Organic–Methods
  • Nitrogen–Chemistry
  • Carbon
  • Nitrogen
ispartof: Chemical Society reviews, October 2011, Vol.40(10), pp.5010-5029
description: Until recently, cross-coupling reactions have been exclusively performed in batch processes. With the advent of microfluidics, significant effort has been devoted to develop a wide variety of continuous-flow techniques to facilitate organic synthesis. In this critical review, we attempt to give an overview of the different continuous-flow methodologies that have been developed and utilized for cross-coupling reactions. In addition, we attempt to point out the advantages of continuous-flow when compared with their batch counterparts (246 references).
language: eng
source:
identifier: E-ISSN: 1460-4744 ; DOI: 10.1039/c1cs15075h
fulltext: fulltext
issn:
  • 14604744
  • 1460-4744
url: Link


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descriptionUntil recently, cross-coupling reactions have been exclusively performed in batch processes. With the advent of microfluidics, significant effort has been devoted to develop a wide variety of continuous-flow techniques to facilitate organic synthesis. In this critical review, we attempt to give an overview of the different continuous-flow methodologies that have been developed and utilized for cross-coupling reactions. In addition, we attempt to point out the advantages of continuous-flow when compared with their batch counterparts (246 references).
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