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Structural basis for membrane targeting by the MVB12-associated [Beta]-prism domain of the human ESCRT-I MVB12 subunit

MVB12-associated β-prism (MABP) domains are predicted to occur in a diverse set of membrane-associated bacterial and eukaryotic proteins, but their existence, structure, and biochemical properties have not been characterized experimentally. Here, we find that the MABP domains of the MVB12A and B sub... Full description

Journal Title: Proceedings of the National Academy of Sciences of the United States of America Feb 7, 2012, Vol.109(6), p.1901
Main Author: Boura, Evzen
Other Authors: Hurley, James
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 00278424 ; E-ISSN: 10916490
Link: http://search.proquest.com/docview/921004521/?pq-origsite=primo
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title: Structural basis for membrane targeting by the MVB12-associated [Beta]-prism domain of the human ESCRT-I MVB12 subunit
format: Article
creator:
  • Boura, Evzen
  • Hurley, James
subjects:
  • Membranes
  • Proteins
  • Molecular Structure
  • Binding Sites
  • Eukaryotes
  • Biochemistry
ispartof: Proceedings of the National Academy of Sciences of the United States of America, Feb 7, 2012, Vol.109(6), p.1901
description: MVB12-associated β-prism (MABP) domains are predicted to occur in a diverse set of membrane-associated bacterial and eukaryotic proteins, but their existence, structure, and biochemical properties have not been characterized experimentally. Here, we find that the MABP domains of the MVB12A and B subunits...
language: eng
source:
identifier: ISSN: 00278424 ; E-ISSN: 10916490
fulltext: fulltext
issn:
  • 00278424
  • 0027-8424
  • 10916490
  • 1091-6490
url: Link


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titleStructural basis for membrane targeting by the MVB12-associated [Beta]-prism domain of the human ESCRT-I MVB12 subunit
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subjectMembranes ; Proteins ; Molecular Structure ; Binding Sites ; Eukaryotes ; Biochemistry
descriptionMVB12-associated β-prism (MABP) domains are predicted to occur in a diverse set of membrane-associated bacterial and eukaryotic proteins, but their existence, structure, and biochemical properties have not been characterized experimentally. Here, we find that the MABP domains of the MVB12A and B subunits...
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titleStructural basis for membrane targeting by the MVB12-associated [Beta]-prism domain of the human ESCRT-I MVB12 subunit
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abstractMVB12-associated β-prism (MABP) domains are predicted to occur in a diverse set of membrane-associated bacterial and eukaryotic proteins, but their existence, structure, and biochemical properties have not been characterized experimentally. Here, we find that the MABP domains of the MVB12A and B subunits...
copWashington
pubNational Academy of Sciences
urlhttp://search.proquest.com/docview/921004521/
pages1901-1906
doi10.1073/pnas.1117597109
date2012-02-07