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Rat brains also have a default mode network.

The default mode network (DMN) in humans has been suggested to support a variety of cognitive functions and has been implicated in an array of neuropsychological disorders. However, its function(s) remains poorly understood. We show that rats possess a DMN that is broadly similar to the DMNs of nonh... Full description

Journal Title: Proceedings of the National Academy of Sciences of the United States of America March 6, 2012, Vol.109(10), pp.3979-3984
Main Author: Lu, Hanbing
Other Authors: Zou, Qihong , Gu, Hong , Raichle, Marcus E , Stein, Elliot A , Yang, Yihong
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1091-6490 ; DOI: 10.1073/pnas.1200506109
Link: http://search.proquest.com/docview/926879689/?pq-origsite=primo
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recordid: proquest926879689
title: Rat brains also have a default mode network.
format: Article
creator:
  • Lu, Hanbing
  • Zou, Qihong
  • Gu, Hong
  • Raichle, Marcus E
  • Stein, Elliot A
  • Yang, Yihong
subjects:
  • Animals–Metabolism
  • Behavior, Animal–Pathology
  • Brain–Physiology
  • Brain Mapping–Methods
  • Haplorhini–Methods
  • Humans–Methods
  • Magnetic Resonance Imaging–Methods
  • Models, Anatomic–Methods
  • Models, Biological–Methods
  • Neural Pathways–Methods
  • Rats–Methods
  • Species Specificity–Methods
ispartof: Proceedings of the National Academy of Sciences of the United States of America, March 6, 2012, Vol.109(10), pp.3979-3984
description: The default mode network (DMN) in humans has been suggested to support a variety of cognitive functions and has been implicated in an array of neuropsychological disorders. However, its function(s) remains poorly understood. We show that rats possess a DMN that is broadly similar to the DMNs of nonhuman primates and humans. Our data suggest that, despite the distinct evolutionary paths between rodent and primate brain, a well-organized, intrinsically coherent DMN appears to be a fundamental feature in the mammalian brain whose primary functions might be to integrate multimodal sensory and affective information to guide behavior in anticipation of changing environmental contingencies. [PUBLICATION ]
language: eng
source:
identifier: E-ISSN: 1091-6490 ; DOI: 10.1073/pnas.1200506109
fulltext: fulltext
issn:
  • 10916490
  • 1091-6490
url: Link


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subjectAnimals–Metabolism ; Behavior, Animal–Pathology ; Brain–Physiology ; Brain Mapping–Methods ; Haplorhini–Methods ; Humans–Methods ; Magnetic Resonance Imaging–Methods ; Models, Anatomic–Methods ; Models, Biological–Methods ; Neural Pathways–Methods ; Rats–Methods ; Species Specificity–Methods
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descriptionThe default mode network (DMN) in humans has been suggested to support a variety of cognitive functions and has been implicated in an array of neuropsychological disorders. However, its function(s) remains poorly understood. We show that rats possess a DMN that is broadly similar to the DMNs of nonhuman primates and humans. Our data suggest that, despite the distinct evolutionary paths between rodent and primate brain, a well-organized, intrinsically coherent DMN appears to be a fundamental feature in the mammalian brain whose primary functions might be to integrate multimodal sensory and affective information to guide behavior in anticipation of changing environmental contingencies. [PUBLICATION ]
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