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Multiplex fluorophore systems on DNA with new diverse fluorescence properties and ability to sense the hybridization dynamics

We developed a multiplexed fluorophore system on a DNA scaffold (MFD) that produced new and diverse fluorescence properties depending on the mixing pattern and sequence that could not be obtained from each monomer fluorophore. Our approach for producing new fluorescence properties is relatively faci... Full description

Journal Title: Chemical Communications 2014, Vol.50(55), pp.7273-7276
Main Author: Lee, Dong Gyu
Other Authors: Kim, In Sun , Park, Jung Woo , Seo, Young Jun
Format: Electronic Article Electronic Article
Language:
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ID: ISSN: 1359-7345 ; E-ISSN: 1364-548X ; DOI: 10.1039/c4cc01378f
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recordid: rscc4cc01378f
title: Multiplex fluorophore systems on DNA with new diverse fluorescence properties and ability to sense the hybridization dynamics
format: Article
creator:
  • Lee, Dong Gyu
  • Kim, In Sun
  • Park, Jung Woo
  • Seo, Young Jun
subjects:
  • DNA -- Chemistry
  • Fluorescent Dyes -- Chemistry
ispartof: Chemical Communications, 2014, Vol.50(55), pp.7273-7276
description: We developed a multiplexed fluorophore system on a DNA scaffold (MFD) that produced new and diverse fluorescence properties depending on the mixing pattern and sequence that could not be obtained from each monomer fluorophore. Our approach for producing new fluorescence properties is relatively facile: simply mixing fluorophores on a DNA scaffold provides large variations in the color and intensity using only one excitation wavelength with high Stokes shifts (190 nm). Furthermore these special fluorescence properties could be controlled by the hybridization pattern and were therefore dependent on the structural changes in DNA.
language:
source:
identifier: ISSN: 1359-7345 ; E-ISSN: 1364-548X ; DOI: 10.1039/c4cc01378f
fulltext: fulltext
issn:
  • 1359-7345
  • 1364-548X
  • 1364548X
  • 13597345
url: Link


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titleMultiplex fluorophore systems on DNA with new diverse fluorescence properties and ability to sense the hybridization dynamics
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descriptionWe developed a multiplexed fluorophore system on a DNA scaffold (MFD) that produced new and diverse fluorescence properties depending on the mixing pattern and sequence that could not be obtained from each monomer fluorophore. Our approach for producing new fluorescence properties is relatively facile: simply mixing fluorophores on a DNA scaffold provides large variations in the color and intensity using only one excitation wavelength with high Stokes shifts (190 nm). Furthermore these special fluorescence properties could be controlled by the hybridization pattern and were therefore dependent on the structural changes in DNA.
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titleMultiplex fluorophore systems on DNA with new diverse fluorescence properties and ability to sense the hybridization dynamics
descriptionWe developed a multiplexed fluorophore system on a DNA scaffold (MFD) that produced new and diverse fluorescence properties depending on the mixing pattern and sequence that could not be obtained from each monomer fluorophore. Our approach for producing new fluorescence properties is relatively facile: simply mixing fluorophores on a DNA scaffold provides large variations in the color and intensity using only one excitation wavelength with high Stokes shifts (190 nm). Furthermore these special fluorescence properties could be controlled by the hybridization pattern and were therefore dependent on the structural changes in DNA.
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titleMultiplex fluorophore systems on DNA with new diverse fluorescence properties and ability to sense the hybridization dynamics
authorLee, Dong Gyu ; Kim, In Sun ; Park, Jung Woo ; Seo, Young Jun
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abstractWe developed a multiplexed fluorophore system on a DNA scaffold (MFD) that produced new and diverse fluorescence properties depending on the mixing pattern and sequence that could not be obtained from each monomer fluorophore. Our approach for producing new fluorescence properties is relatively facile: simply mixing fluorophores on a DNA scaffold provides large variations in the color and intensity using only one excitation wavelength with high Stokes shifts (190 nm). Furthermore these special fluorescence properties could be controlled by the hybridization pattern and were therefore dependent on the structural changes in DNA.
doi10.1039/c4cc01378f
pages7273-7276
date2014-06-12