schliessen

Filtern

 

Bibliotheken

A novel approach to measure local cerebral haematocrit using MRI

The percentage blood volume occupied by red blood cells is known as haematocrit. While it is straightforward to measure haematocrit in large arteries, it is very challenging to do it in microvasculature (cerebral haematocrit). Currently, this can only be done using invasive methods (e.g. PET), but t... Full description

Journal Title: Journal of Cerebral Blood Flow & Metabolism April 2016, Vol.36(4), pp.768-780
Main Author: Calamante, Fernando
Other Authors: Ahlgren, André , van Osch, Matthias JP , Knutsson, Linda
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0271-678X ; E-ISSN: 1559-7016 ; DOI: 10.1177/0271678X15606143
Link: https://journals.sagepub.com/doi/full/10.1177/0271678X15606143
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: sage_s10_1177_0271678X15606143
title: A novel approach to measure local cerebral haematocrit using MRI
format: Article
creator:
  • Calamante, Fernando
  • Ahlgren, André
  • van Osch, Matthias JP
  • Knutsson, Linda
subjects:
  • Haematocrit
  • Perfusion Mri
  • Arterial Spin Labelling
  • Cerebral Blood Flow
  • Cerebral Blood Volume
  • Chemistry
  • Anatomy & Physiology
ispartof: Journal of Cerebral Blood Flow & Metabolism, April 2016, Vol.36(4), pp.768-780
description: The percentage blood volume occupied by red blood cells is known as haematocrit. While it is straightforward to measure haematocrit in large arteries, it is very challenging to do it in microvasculature (cerebral haematocrit). Currently, this can only be done using invasive methods (e.g. PET), but their use is very limited. Local variations in cerebral haematocrit have been reported in various brain abnormalities (e.g. stroke, tumours). We propose a new approach to image cerebral haematocrit using MRI, which relies on combining data from two measurements: one that provides haematocrit-weighted and other one haematocrit-independent values of the same parameter, thus providing an easily obtainable measurement of this important physiological parameter. Four different implementations are described, with one illustrated as proof-of-concept using data from healthy subjects. Cerebral haematocrit measurements were found to be in general agreement with literature values from invasive...
language: eng
source:
identifier: ISSN: 0271-678X ; E-ISSN: 1559-7016 ; DOI: 10.1177/0271678X15606143
fulltext: fulltext
issn:
  • 0271-678X
  • 0271678X
  • 1559-7016
  • 15597016
url: Link


@attributes
ID199802821
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid10_1177_0271678X15606143
sourceidsage_s
recordidTN_sage_s10_1177_0271678X15606143
sourcesystemPC
dbid
054M
1AAGMC
2AAMGE
3AAMPI
4AARDL
5AATBZ
6AAUAS
7ABAWP
8ABJUO
9ABNCE
10ABNLC
11ABQXT
12ABXGC
13ACDXX
14ACGZU
15ACJTF
16ACTQU
17ADGDL
18AECGH
19AEUIJ
20AGWFA
21AIFIH
22AMCVQ
23BFDSU
24BKSCU
25DC.
26DV7
27J8X
28K.F
29SCNPE
30SFC
31SHG
32SPQ
33SPV
pqid1777984455
display
typearticle
titleA novel approach to measure local cerebral haematocrit using MRI
creatorCalamante, Fernando ; Ahlgren, André ; van Osch, Matthias JP ; Knutsson, Linda
ispartofJournal of Cerebral Blood Flow & Metabolism, April 2016, Vol.36(4), pp.768-780
identifier
subjectHaematocrit ; Perfusion Mri ; Arterial Spin Labelling ; Cerebral Blood Flow ; Cerebral Blood Volume ; Chemistry ; Anatomy & Physiology
descriptionThe percentage blood volume occupied by red blood cells is known as haematocrit. While it is straightforward to measure haematocrit in large arteries, it is very challenging to do it in microvasculature (cerebral haematocrit). Currently, this can only be done using invasive methods (e.g. PET), but their use is very limited. Local variations in cerebral haematocrit have been reported in various brain abnormalities (e.g. stroke, tumours). We propose a new approach to image cerebral haematocrit using MRI, which relies on combining data from two measurements: one that provides haematocrit-weighted and other one haematocrit-independent values of the same parameter, thus providing an easily obtainable measurement of this important physiological parameter. Four different implementations are described, with one illustrated as proof-of-concept using data from healthy subjects. Cerebral haematocrit measurements were found to be in general agreement with literature values from invasive...
languageeng
source
version6
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
backlink$$Uhttps://journals.sagepub.com/doi/full/10.1177/0271678X15606143$$EView_record_in_Sage_(Access_to_full_text_may_be_restricted)
search
creatorcontrib
0Calamante, Fernando
1Ahlgren, André
2van Osch, Matthias JP
3Knutsson, Linda
titleA novel approach to measure local cerebral haematocrit using MRI
description

The percentage blood volume occupied by red blood cells is known as haematocrit. While it is straightforward to measure haematocrit in large arteries, it is very challenging to do it in microvasculature (cerebral haematocrit). Currently, this can only be done using invasive methods (e.g. PET), but their use is very limited. Local variations in cerebral haematocrit have been reported in various brain abnormalities (e.g. stroke, tumours). We propose a new approach to image cerebral haematocrit using MRI, which relies on combining data from two measurements: one that provides haematocrit-weighted and other one haematocrit-independent values of the same parameter, thus providing an easily obtainable measurement of this important physiological parameter. Four different implementations are described, with one illustrated as proof-of-concept using data from healthy subjects. Cerebral haematocrit measurements were found to be in general agreement with literature values from invasive...

subject
0Haematocrit
1Perfusion Mri
2Arterial Spin Labelling
3Cerebral Blood Flow
4Cerebral Blood Volume
5Chemistry
6Anatomy & Physiology
general
0English
1SAGE Publications
210.1177/0271678X15606143
3Sage Journals (Sage Publications)
4SAGE Clinical Medicine (Sage Publications)
5SAGE Health Sciences (Sage Publications)
6SAGE STM (Sage Publications)
7SAGE Neurology (Sage Publications)
8SAGE Cardiology and Cardiovascular Medicine (Sage Publications)
9SAGE Communication and Media Studies (Sage Publications)
10SAGE Journals (Sage Publications)
sourceidsage_s
recordidsage_s10_1177_0271678X15606143
issn
00271-678X
10271678X
21559-7016
315597016
rsrctypearticle
creationdate2016
addtitleJournal of Cerebral Blood Flow & Metabolism
searchscope
0sage_full
1sage32
2sage27
3sage44
4sage219
5sage139
6sage255
7sage29
8sage269
9sage220
10sage183
11sage270
12sage221
13sage17
14sage134
15sage28
16sage273
17sage257
18sage135
19sage272
20sage256
21sage264
22sage136
23sage263
24sage30
25sage282
26sage42
27sage40
28sage31
29sage11
30sage35
31sage34
32sage33
scope
0sage_full
1sage32
2sage27
3sage44
4sage219
5sage139
6sage255
7sage29
8sage269
9sage220
10sage183
11sage270
12sage221
13sage17
14sage134
15sage28
16sage273
17sage257
18sage135
19sage272
20sage256
21sage264
22sage136
23sage263
24sage30
25sage282
26sage42
27sage40
28sage31
29sage11
30sage35
31sage34
32sage33
lsr44$$EView_record_in_Sage_(Access_to_full_text_may_be_restricted)
tmp01
0Sage Journals (Sage Publications)
1SAGE Clinical Medicine (Sage Publications)
2SAGE Health Sciences (Sage Publications)
3SAGE STM (Sage Publications)
4SAGE Neurology (Sage Publications)
5SAGE Cardiology and Cardiovascular Medicine (Sage Publications)
6SAGE Communication and Media Studies (Sage Publications)
7SAGE Journals (Sage Publications)
tmp02
054M
1AAGMC
2AAMGE
3AAMPI
4AARDL
5AATBZ
6AAUAS
7ABAWP
8ABJUO
9ABNCE
10ABNLC
11ABQXT
12ABXGC
13ACDXX
14ACGZU
15ACJTF
16ACTQU
17ADGDL
18AECGH
19AEUIJ
20AGWFA
21AIFIH
22AMCVQ
23BFDSU
24BKSCU
25DC.
26DV7
27J8X
28K.F
29SCNPE
30SFC
31SHG
32SPQ
33SPV
startdate20160401
enddate20160431
lsr40Journal of Cerebral Blood Flow & Metabolism, April 2016, Vol.36 (4), pp.768-780
doi10.1177/0271678X15606143
citationpf 768 pt 780 vol 36 issue 4
lsr30VSR-Enriched:[pqid]
sort
titleA novel approach to measure local cerebral haematocrit using MRI
authorCalamante, Fernando ; Ahlgren, André ; van Osch, Matthias JP ; Knutsson, Linda
creationdate20160400
lso0120160400
facets
frbrgroupid2556538532766069931
frbrtype5
newrecords20170607
languageeng
topic
0Haematocrit
1Perfusion Mri
2Arterial Spin Labelling
3Cerebral Blood Flow
4Cerebral Blood Volume
5Chemistry
6Anatomy & Physiology
collectionSage Journals (Sage Publications)
prefilterarticles
rsrctypearticles
creatorcontrib
0Calamante, Fernando
1Ahlgren, André
2van Osch, Matthias JP
3Knutsson, Linda
jtitleJournal of Cerebral Blood Flow & Metabolism
creationdate2016
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Calamante
1Ahlgren
2van Osch
3Knutsson
aufirst
0Fernando
1André
2Matthias JP
3Linda
auinitF
auinit1F
au
0Calamante, Fernando
1Ahlgren, André
2van Osch, Matthias JP
3Knutsson, Linda
atitleA novel approach to measure local cerebral haematocrit using MRI
jtitleJournal of Cerebral Blood Flow & Metabolism
risdate201604
volume36
issue4
spage768
epage780
pages768-780
issn0271-678X
eissn1559-7016
formatjournal
genrearticle
ristypeJOUR
abstract

The percentage blood volume occupied by red blood cells is known as haematocrit. While it is straightforward to measure haematocrit in large arteries, it is very challenging to do it in microvasculature (cerebral haematocrit). Currently, this can only be done using invasive methods (e.g. PET), but their use is very limited. Local variations in cerebral haematocrit have been reported in various brain abnormalities (e.g. stroke, tumours). We propose a new approach to image cerebral haematocrit using MRI, which relies on combining data from two measurements: one that provides haematocrit-weighted and other one haematocrit-independent values of the same parameter, thus providing an easily obtainable measurement of this important physiological parameter. Four different implementations are described, with one illustrated as proof-of-concept using data from healthy subjects. Cerebral haematocrit measurements were found to be in general agreement with literature values from invasive...

copLondon, England
pubSAGE Publications
doi10.1177/0271678X15606143
lad01Journal of Cerebral Blood Flow & Metabolism
date2016-04