schliessen

Filtern

 

Bibliotheken

Characterization of full-length MHC class II sequences in Indonesian and Vietnamese cynomolgus macaques

In recent years, the use of cynomolgus macaques in biomedical research has increased greatly. However, with the exception of the Mauritian population, knowledge of the MHC class II genetics of the species remains limited. Here, using cDNA cloning and Sanger sequencing, we identified 127 full-length... Full description

Journal Title: Immunogenetics 2011, Vol.63(9), pp.611-618
Main Author: Creager, Hannah
Other Authors: Becker, Ericka , Sandman, Kelly , Karl, Julie , Lank, Simon , Bimber, Benjamin , Wiseman, Roger , Hughes, Austin , O’Connor, Shelby , O’Connor, David
Format: Electronic Article Electronic Article
Language: English
Subjects:
MHC
ID: ISSN: 0093-7711 ; E-ISSN: 1432-1211 ; DOI: 10.1007/s00251-011-0537-5
Link: http://dx.doi.org/10.1007/s00251-011-0537-5
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: springer_jour10.1007/s00251-011-0537-5
title: Characterization of full-length MHC class II sequences in Indonesian and Vietnamese cynomolgus macaques
format: Article
creator:
  • Creager, Hannah
  • Becker, Ericka
  • Sandman, Kelly
  • Karl, Julie
  • Lank, Simon
  • Bimber, Benjamin
  • Wiseman, Roger
  • Hughes, Austin
  • O’Connor, Shelby
  • O’Connor, David
subjects:
  • Macaca fascicularis
  • Cynomolgus macaques
  • MHC
  • Immunogenetics
ispartof: Immunogenetics, 2011, Vol.63(9), pp.611-618
description: In recent years, the use of cynomolgus macaques in biomedical research has increased greatly. However, with the exception of the Mauritian population, knowledge of the MHC class II genetics of the species remains limited. Here, using cDNA cloning and Sanger sequencing, we identified 127 full-length MHC class II alleles in a group of 12 Indonesian and 12 Vietnamese cynomolgus macaques. Forty two of these were completely novel to cynomolgus macaques while 61 extended the sequence of previously identified alleles from partial to full length. This more than doubles the number of full-length cynomolgus macaque MHC class II alleles available in GenBank, significantly expanding the allele library for the species and laying the groundwork for future evolutionary and functional studies.
language: eng
source:
identifier: ISSN: 0093-7711 ; E-ISSN: 1432-1211 ; DOI: 10.1007/s00251-011-0537-5
fulltext: fulltext
issn:
  • 1432-1211
  • 14321211
  • 0093-7711
  • 00937711
url: Link


@attributes
ID263591962
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid10.1007/s00251-011-0537-5
sourceidspringer_jour
recordidTN_springer_jour10.1007/s00251-011-0537-5
sourcesystemOther
pqid883847423
galeid264219790
display
typearticle
titleCharacterization of full-length MHC class II sequences in Indonesian and Vietnamese cynomolgus macaques
creatorCreager, Hannah ; Becker, Ericka ; Sandman, Kelly ; Karl, Julie ; Lank, Simon ; Bimber, Benjamin ; Wiseman, Roger ; Hughes, Austin ; O’Connor, Shelby ; O’Connor, David
ispartofImmunogenetics, 2011, Vol.63(9), pp.611-618
identifier
subjectMacaca fascicularis ; Cynomolgus macaques ; MHC ; Immunogenetics
descriptionIn recent years, the use of cynomolgus macaques in biomedical research has increased greatly. However, with the exception of the Mauritian population, knowledge of the MHC class II genetics of the species remains limited. Here, using cDNA cloning and Sanger sequencing, we identified 127 full-length MHC class II alleles in a group of 12 Indonesian and 12 Vietnamese cynomolgus macaques. Forty two of these were completely novel to cynomolgus macaques while 61 extended the sequence of previously identified alleles from partial to full length. This more than doubles the number of full-length cynomolgus macaque MHC class II alleles available in GenBank, significantly expanding the allele library for the species and laying the groundwork for future evolutionary and functional studies.
languageeng
source
version7
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
backlink$$Uhttp://dx.doi.org/10.1007/s00251-011-0537-5$$EView_full_text_in_Springer_(Subscribers_only)
search
creatorcontrib
0Creager, Hannah, M.
1Becker, Ericka, A.
2Sandman, Kelly, K.
3Karl, Julie, A.
4Lank, Simon, M.
5Bimber, Benjamin, N.
6Wiseman, Roger, W.
7Hughes, Austin, L
8O’Connor, Shelby, L.
9O’Connor, David, H.
titleCharacterization of full-length MHC class II sequences in Indonesian and Vietnamese cynomolgus macaques
descriptionIn recent years, the use of cynomolgus macaques in biomedical research has increased greatly. However, with the exception of the Mauritian population, knowledge of the MHC class II genetics of the species remains limited. Here, using cDNA cloning and Sanger sequencing, we identified 127 full-length MHC class II alleles in a group of 12 Indonesian and 12 Vietnamese cynomolgus macaques. Forty two of these were completely novel to cynomolgus macaques while 61 extended the sequence of previously identified alleles from partial to full length. This more than doubles the number of full-length cynomolgus macaque MHC class II alleles available in GenBank, significantly expanding the allele library for the species and laying the groundwork for future evolutionary and functional studies.
subject
0Macaca fascicularis
1Cynomolgus macaques
2MHC
3Immunogenetics
general
010.1007/s00251-011-0537-5
1English
2Springer Science & Business Media B.V.
3SpringerLink
sourceidspringer_jour
recordidspringer_jour10.1007/s00251-011-0537-5
issn
01432-1211
114321211
20093-7711
300937711
rsrctypearticle
creationdate2011
addtitleImmunogenetics
searchscopespringer_journals_complete
scopespringer_journals_complete
lsr30VSR-Enriched:[pages, pqid, galeid]
sort
titleCharacterization of full-length MHC class II sequences in Indonesian and Vietnamese cynomolgus macaques
authorCreager, Hannah ; Becker, Ericka ; Sandman, Kelly ; Karl, Julie ; Lank, Simon ; Bimber, Benjamin ; Wiseman, Roger ; Hughes, Austin ; O’Connor, Shelby ; O’Connor, David
creationdate20110900
facets
frbrgroupid5079620465037975260
frbrtype5
languageeng
creationdate2011
topic
0Macaca Fascicularis
1Cynomolgus Macaques
2Mhc
3Immunogenetics
collectionSpringerLink
prefilterarticles
rsrctypearticles
creatorcontrib
0Creager, Hannah
1Becker, Ericka
2Sandman, Kelly
3Karl, Julie
4Lank, Simon
5Bimber, Benjamin
6Wiseman, Roger
7Hughes, Austin
8O’Connor, Shelby
9O’Connor, David
jtitleImmunogenetics
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Creager
1Becker
2Sandman
3Karl
4Lank
5Bimber
6Wiseman
7Hughes
8O’Connor
aufirst
0Hannah
1M.
2Ericka
3A.
4Kelly
5K.
6Julie
7Simon
8Benjamin
9N.
10Roger
11W.
12Austin
13L
14Shelby
15L.
16David
17H.
au
0Creager, Hannah
1Becker, Ericka
2Sandman, Kelly
3Karl, Julie
4Lank, Simon
5Bimber, Benjamin
6Wiseman, Roger
7Hughes, Austin
8O’Connor, Shelby
9O’Connor, David
atitleCharacterization of full-length MHC class II sequences in Indonesian and Vietnamese cynomolgus macaques
jtitleImmunogenetics
stitleImmunogenetics
risdate201109
volume63
issue9
spage611
epage618
issn0093-7711
eissn1432-1211
genrearticle
ristypeJOUR
abstractIn recent years, the use of cynomolgus macaques in biomedical research has increased greatly. However, with the exception of the Mauritian population, knowledge of the MHC class II genetics of the species remains limited. Here, using cDNA cloning and Sanger sequencing, we identified 127 full-length MHC class II alleles in a group of 12 Indonesian and 12 Vietnamese cynomolgus macaques. Forty two of these were completely novel to cynomolgus macaques while 61 extended the sequence of previously identified alleles from partial to full length. This more than doubles the number of full-length cynomolgus macaque MHC class II alleles available in GenBank, significantly expanding the allele library for the species and laying the groundwork for future evolutionary and functional studies.
copBerlin/Heidelberg
pubSpringer-Verlag
doi10.1007/s00251-011-0537-5
pages611-618
date2011-09