schliessen

Filtern

 

Bibliotheken

Enhanced characterization of the zebrafish brain as revealed by super-resolution track-density imaging

In this study, we explored the use of super-resolution track-density imaging (TDI) for neuroanatomical characterization of the adult zebrafish brain. We compared the quality of image contrast and resolution obtained with T 2 * magnetic resonance imaging (MRI), diffusion tensor-based imaging (DTI), T... Full description

Journal Title: Brain Structure and Function 2015, Vol.220(1), pp.457-468
Main Author: Ullmann, Jeremy
Other Authors: Calamante, Fernando , Collin, Shaun , Reutens, David , Kurniawan, Nyoman
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 1863-2653 ; E-ISSN: 1863-2661 ; DOI: 10.1007/s00429-013-0667-7
Link: http://dx.doi.org/10.1007/s00429-013-0667-7
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: springer_jour10.1007/s00429-013-0667-7
title: Enhanced characterization of the zebrafish brain as revealed by super-resolution track-density imaging
format: Article
creator:
  • Ullmann, Jeremy
  • Calamante, Fernando
  • Collin, Shaun
  • Reutens, David
  • Kurniawan, Nyoman
subjects:
  • Zebrafish
  • Brain
  • Magnetic resonance
  • Diffusion-weighted imaging
  • Track-density imaging
  • Probabilistic tractography
ispartof: Brain Structure and Function, 2015, Vol.220(1), pp.457-468
description: In this study, we explored the use of super-resolution track-density imaging (TDI) for neuroanatomical characterization of the adult zebrafish brain. We compared the quality of image contrast and resolution obtained with T 2 * magnetic resonance imaging (MRI), diffusion tensor-based imaging (DTI), TDI, and histology. The anatomical structures visualized in 5 μm TDI maps corresponded with histology. Moreover, the super-resolution property and the local-directional information provided by directionally encoded color TDI facilitated delineation of a larger number of brain regions, commissures and small white matter tracks when compared to conventional MRI and DTI. In total, we were able to visualize 17 structures that were previously unidentifiable using MR microimaging, such as the four layers of the optic tectum. This study demonstrates the use of TDI for characterization of the adult zebrafish brain as a pivotal tool for future phenotypic examination of transgenic models of neurological diseases.
language: eng
source:
identifier: ISSN: 1863-2653 ; E-ISSN: 1863-2661 ; DOI: 10.1007/s00429-013-0667-7
fulltext: fulltext
issn:
  • 1863-2661
  • 18632661
  • 1863-2653
  • 18632653
url: Link


@attributes
ID313639075
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid10.1007/s00429-013-0667-7
sourceidspringer_jour
recordidTN_springer_jour10.1007/s00429-013-0667-7
sourcesystemOther
pqid1654682528
galeid396536294
display
typearticle
titleEnhanced characterization of the zebrafish brain as revealed by super-resolution track-density imaging
creatorUllmann, Jeremy ; Calamante, Fernando ; Collin, Shaun ; Reutens, David ; Kurniawan, Nyoman
ispartofBrain Structure and Function, 2015, Vol.220(1), pp.457-468
identifier
subjectZebrafish ; Brain ; Magnetic resonance ; Diffusion-weighted imaging ; Track-density imaging ; Probabilistic tractography
descriptionIn this study, we explored the use of super-resolution track-density imaging (TDI) for neuroanatomical characterization of the adult zebrafish brain. We compared the quality of image contrast and resolution obtained with T 2 * magnetic resonance imaging (MRI), diffusion tensor-based imaging (DTI), TDI, and histology. The anatomical structures visualized in 5 μm TDI maps corresponded with histology. Moreover, the super-resolution property and the local-directional information provided by directionally encoded color TDI facilitated delineation of a larger number of brain regions, commissures and small white matter tracks when compared to conventional MRI and DTI. In total, we were able to visualize 17 structures that were previously unidentifiable using MR microimaging, such as the four layers of the optic tectum. This study demonstrates the use of TDI for characterization of the adult zebrafish brain as a pivotal tool for future phenotypic examination of transgenic models of neurological diseases.
languageeng
source
version6
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
backlink$$Uhttp://dx.doi.org/10.1007/s00429-013-0667-7$$EView_full_text_in_Springer_(Subscribers_only)
search
creatorcontrib
0Ullmann, Jeremy, F.
1Calamante, Fernando, P.
2Collin, Shaun, C.
3Reutens, David, D.
4Kurniawan, Nyoman, D.
titleEnhanced characterization of the zebrafish brain as revealed by super-resolution track-density imaging
descriptionIn this study, we explored the use of super-resolution track-density imaging (TDI) for neuroanatomical characterization of the adult zebrafish brain. We compared the quality of image contrast and resolution obtained with T 2 * magnetic resonance imaging (MRI), diffusion tensor-based imaging (DTI), TDI, and histology. The anatomical structures visualized in 5 μm TDI maps corresponded with histology. Moreover, the super-resolution property and the local-directional information provided by directionally encoded color TDI facilitated delineation of a larger number of brain regions, commissures and small white matter tracks when compared to conventional MRI and DTI. In total, we were able to visualize 17 structures that were previously unidentifiable using MR microimaging, such as the four layers of the optic tectum. This study demonstrates the use of TDI for characterization of the adult zebrafish brain as a pivotal tool for future phenotypic examination of transgenic models of neurological diseases.
subject
0Zebrafish
1Brain
2Magnetic resonance
3Diffusion-weighted imaging
4Track-density imaging
5Probabilistic tractography
general
010.1007/s00429-013-0667-7
1English
2Springer Science & Business Media B.V.
3SpringerLink
sourceidspringer_jour
recordidspringer_jour10.1007/s00429-013-0667-7
issn
01863-2661
118632661
21863-2653
318632653
rsrctypearticle
creationdate2015
addtitle
0Brain Structure and Function
1Brain Struct Funct
searchscopespringer_journals_complete
scopespringer_journals_complete
lsr30VSR-Enriched:[pqid, galeid, pages]
sort
titleEnhanced characterization of the zebrafish brain as revealed by super-resolution track-density imaging
authorUllmann, Jeremy ; Calamante, Fernando ; Collin, Shaun ; Reutens, David ; Kurniawan, Nyoman
creationdate20150100
facets
frbrgroupid6419665380162522311
frbrtype5
languageeng
creationdate2015
topic
0Zebrafish
1Brain
2Magnetic Resonance
3Diffusion-Weighted Imaging
4Track-Density Imaging
5Probabilistic Tractography
collectionSpringerLink
prefilterarticles
rsrctypearticles
creatorcontrib
0Ullmann, Jeremy
1Calamante, Fernando
2Collin, Shaun
3Reutens, David
4Kurniawan, Nyoman
jtitleBrain Structure And Function
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Ullmann
1Calamante
2Collin
3Reutens
4Kurniawan
aufirst
0Jeremy
1F.
2P.
3Fernando
4Shaun
5David
6C.
7Nyoman
8D.
au
0Ullmann, Jeremy
1Calamante, Fernando
2Collin, Shaun
3Reutens, David
4Kurniawan, Nyoman
atitleEnhanced characterization of the zebrafish brain as revealed by super-resolution track-density imaging
jtitleBrain Structure and Function
stitleBrain Struct Funct
risdate201501
volume220
issue1
spage457
epage468
issn1863-2653
eissn1863-2661
genrearticle
ristypeJOUR
abstractIn this study, we explored the use of super-resolution track-density imaging (TDI) for neuroanatomical characterization of the adult zebrafish brain. We compared the quality of image contrast and resolution obtained with T 2 * magnetic resonance imaging (MRI), diffusion tensor-based imaging (DTI), TDI, and histology. The anatomical structures visualized in 5 μm TDI maps corresponded with histology. Moreover, the super-resolution property and the local-directional information provided by directionally encoded color TDI facilitated delineation of a larger number of brain regions, commissures and small white matter tracks when compared to conventional MRI and DTI. In total, we were able to visualize 17 structures that were previously unidentifiable using MR microimaging, such as the four layers of the optic tectum. This study demonstrates the use of TDI for characterization of the adult zebrafish brain as a pivotal tool for future phenotypic examination of transgenic models of neurological diseases.
copBerlin/Heidelberg
pubSpringer Berlin Heidelberg
doi10.1007/s00429-013-0667-7
pages457-468
date2015-01