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Resolution of chyloperitoneum in a preterm with octreotide, diet and cessation of dialysis

The diagnosis of chyloperitoneum (CP) is based on the presence of high levels of triglycerides (TGs) in the dialysate. It is a rare complication of peritoneal dialysis (PD) and even rarer in neonates. We report here the case of CP in a 1700-g male baby delivered at the 30th gestational week due to p... Full description

Journal Title: Pediatric Nephrology 2010, Vol.25(2), pp.363-366
Main Author: Soylu, Alper
Other Authors: Alaygut, Demet , Yeşilırmak, Didem , Kasap, Belde , Türkmen, Mehmet , Duman, Nuray , Kavukçu, Salih
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0931-041X ; E-ISSN: 1432-198X ; DOI: 10.1007/s00467-009-1340-5
Link: http://dx.doi.org/10.1007/s00467-009-1340-5
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recordid: springer_jour10.1007/s00467-009-1340-5
title: Resolution of chyloperitoneum in a preterm with octreotide, diet and cessation of dialysis
format: Article
creator:
  • Soylu, Alper
  • Alaygut, Demet
  • Yeşilırmak, Didem
  • Kasap, Belde
  • Türkmen, Mehmet
  • Duman, Nuray
  • Kavukçu, Salih
subjects:
  • Chyloperitoneum
  • Octreotide
  • Peritoneal dialysis
  • Preterm
ispartof: Pediatric Nephrology, 2010, Vol.25(2), pp.363-366
description: The diagnosis of chyloperitoneum (CP) is based on the presence of high levels of triglycerides (TGs) in the dialysate. It is a rare complication of peritoneal dialysis (PD) and even rarer in neonates. We report here the case of CP in a 1700-g male baby delivered at the 30th gestational week due to posterior urethral valve and associated oligohydramnios. On postnatal day 2, the serum creatinine (Scr) was 1.6 mg/dL, and he was anuric. PD was instituted via a Tenckhoff catheter. At the end of the second week, after the initiation of enteral feeding, the ultrafiltrate became cloudy, with a leukocyte count of 900/mm 3 . A treatment regimen consisting of intraperitoneal vancomycin and ceftazidime was then started. Five days later, the fluid became milky, with a TG level of 251 mg/dL. The patient was then placed on a diet based on medium-chain triglycerides and octreotide (1 μg/kg/h; increasing up to 2 μg/kg/h over 15 days). Although the TG and leukocyte levels decreased, the milky appearance persisted. PD was stopped for 2 days when the Scr decreased to 1.7 mg/dL. When it was resumed, the fluid was totally clear, with a TG level of 7 mg/dL. The infant was discharged with a nightly intermittent peritoneal dialysis program and has had no recurrence. In summary, we report a preterm infant who developed CP during PD and recovered following treatment that included diet modification, octreotide, and temporary discontinuation of the PD.
language: eng
source:
identifier: ISSN: 0931-041X ; E-ISSN: 1432-198X ; DOI: 10.1007/s00467-009-1340-5
fulltext: fulltext
issn:
  • 1432-198X
  • 1432198X
  • 0931-041X
  • 0931041X
url: Link


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titleResolution of chyloperitoneum in a preterm with octreotide, diet and cessation of dialysis
creatorSoylu, Alper ; Alaygut, Demet ; Yeşilırmak, Didem ; Kasap, Belde ; Türkmen, Mehmet ; Duman, Nuray ; Kavukçu, Salih
ispartofPediatric Nephrology, 2010, Vol.25(2), pp.363-366
identifier
subjectChyloperitoneum ; Octreotide ; Peritoneal dialysis ; Preterm
descriptionThe diagnosis of chyloperitoneum (CP) is based on the presence of high levels of triglycerides (TGs) in the dialysate. It is a rare complication of peritoneal dialysis (PD) and even rarer in neonates. We report here the case of CP in a 1700-g male baby delivered at the 30th gestational week due to posterior urethral valve and associated oligohydramnios. On postnatal day 2, the serum creatinine (Scr) was 1.6 mg/dL, and he was anuric. PD was instituted via a Tenckhoff catheter. At the end of the second week, after the initiation of enteral feeding, the ultrafiltrate became cloudy, with a leukocyte count of 900/mm 3 . A treatment regimen consisting of intraperitoneal vancomycin and ceftazidime was then started. Five days later, the fluid became milky, with a TG level of 251 mg/dL. The patient was then placed on a diet based on medium-chain triglycerides and octreotide (1 μg/kg/h; increasing up to 2 μg/kg/h over 15 days). Although the TG and leukocyte levels decreased, the milky appearance persisted. PD was stopped for 2 days when the Scr decreased to 1.7 mg/dL. When it was resumed, the fluid was totally clear, with a TG level of 7 mg/dL. The infant was discharged with a nightly intermittent peritoneal dialysis program and has had no recurrence. In summary, we report a preterm infant who developed CP during PD and recovered following treatment that included diet modification, octreotide, and temporary discontinuation of the PD.
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titleResolution of chyloperitoneum in a preterm with octreotide, diet and cessation of dialysis
descriptionThe diagnosis of chyloperitoneum (CP) is based on the presence of high levels of triglycerides (TGs) in the dialysate. It is a rare complication of peritoneal dialysis (PD) and even rarer in neonates. We report here the case of CP in a 1700-g male baby delivered at the 30th gestational week due to posterior urethral valve and associated oligohydramnios. On postnatal day 2, the serum creatinine (Scr) was 1.6 mg/dL, and he was anuric. PD was instituted via a Tenckhoff catheter. At the end of the second week, after the initiation of enteral feeding, the ultrafiltrate became cloudy, with a leukocyte count of 900/mm 3 . A treatment regimen consisting of intraperitoneal vancomycin and ceftazidime was then started. Five days later, the fluid became milky, with a TG level of 251 mg/dL. The patient was then placed on a diet based on medium-chain triglycerides and octreotide (1 μg/kg/h; increasing up to 2 μg/kg/h over 15 days). Although the TG and leukocyte levels decreased, the milky appearance persisted. PD was stopped for 2 days when the Scr decreased to 1.7 mg/dL. When it was resumed, the fluid was totally clear, with a TG level of 7 mg/dL. The infant was discharged with a nightly intermittent peritoneal dialysis program and has had no recurrence. In summary, we report a preterm infant who developed CP during PD and recovered following treatment that included diet modification, octreotide, and temporary discontinuation of the PD.
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abstractThe diagnosis of chyloperitoneum (CP) is based on the presence of high levels of triglycerides (TGs) in the dialysate. It is a rare complication of peritoneal dialysis (PD) and even rarer in neonates. We report here the case of CP in a 1700-g male baby delivered at the 30th gestational week due to posterior urethral valve and associated oligohydramnios. On postnatal day 2, the serum creatinine (Scr) was 1.6 mg/dL, and he was anuric. PD was instituted via a Tenckhoff catheter. At the end of the second week, after the initiation of enteral feeding, the ultrafiltrate became cloudy, with a leukocyte count of 900/mm 3 . A treatment regimen consisting of intraperitoneal vancomycin and ceftazidime was then started. Five days later, the fluid became milky, with a TG level of 251 mg/dL. The patient was then placed on a diet based on medium-chain triglycerides and octreotide (1 μg/kg/h; increasing up to 2 μg/kg/h over 15 days). Although the TG and leukocyte levels decreased, the milky appearance persisted. PD was stopped for 2 days when the Scr decreased to 1.7 mg/dL. When it was resumed, the fluid was totally clear, with a TG level of 7 mg/dL. The infant was discharged with a nightly intermittent peritoneal dialysis program and has had no recurrence. In summary, we report a preterm infant who developed CP during PD and recovered following treatment that included diet modification, octreotide, and temporary discontinuation of the PD.
copBerlin/Heidelberg
pubSpringer-Verlag
doi10.1007/s00467-009-1340-5
pages363-366
date2010-02