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Isorosthornins A-C, new ent -kaurane diterpenoids from Isodon rosthornii

Three new ent -kauranoids, isorosthornins A-C ( 1–3 ), and a new natural product, dihydroponicidin ( 4 ), together with five known ones were isolated from the aerial parts of Isodon rosthornii . The structures were determined by means of extensive spectroscopic analysis. All diterpenoids isolated we... Full description

Journal Title: Natural Products and Bioprospecting 2011, Vol.1(3), pp.116-120
Main Author: Zhan, Rui
Other Authors: Du, Xue , Su, Jia , Li, Xiao-Nian , Wang, Wei-Guang , Liang, Cheng-Qin , Yang, Jian-Hong , Li, Yan , Pu, Jian-Xin , Sun, Han-Dong
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 2192-2195 ; E-ISSN: 2192-2209 ; DOI: 10.1007/s13659-011-0031-7
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recordid: springer_jour10.1007/s13659-011-0031-7
title: Isorosthornins A-C, new ent -kaurane diterpenoids from Isodon rosthornii
format: Article
creator:
  • Zhan, Rui
  • Du, Xue
  • Su, Jia
  • Li, Xiao-Nian
  • Wang, Wei-Guang
  • Liang, Cheng-Qin
  • Yang, Jian-Hong
  • Li, Yan
  • Pu, Jian-Xin
  • Sun, Han-Dong
subjects:
  • Isodon rosthornii
  • -kaurane diterpenoid
  • cytotoxicity
ispartof: Natural Products and Bioprospecting, 2011, Vol.1(3), pp.116-120
description: Three new ent -kauranoids, isorosthornins A-C ( 1–3 ), and a new natural product, dihydroponicidin ( 4 ), together with five known ones were isolated from the aerial parts of Isodon rosthornii . The structures were determined by means of extensive spectroscopic analysis. All diterpenoids isolated were evaluated for their cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines, and compounds 5 and 7 showed significant inhibitory effects on all cell lines.
language: eng
source:
identifier: ISSN: 2192-2195 ; E-ISSN: 2192-2209 ; DOI: 10.1007/s13659-011-0031-7
fulltext: fulltext_linktorsrc
issn:
  • 2192-2209
  • 21922209
  • 2192-2195
  • 21922195
url: Link


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titleIsorosthornins A-C, new ent -kaurane diterpenoids from Isodon rosthornii
creatorZhan, Rui ; Du, Xue ; Su, Jia ; Li, Xiao-Nian ; Wang, Wei-Guang ; Liang, Cheng-Qin ; Yang, Jian-Hong ; Li, Yan ; Pu, Jian-Xin ; Sun, Han-Dong
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subjectIsodon rosthornii ; -kaurane diterpenoid ; cytotoxicity
descriptionThree new ent -kauranoids, isorosthornins A-C ( 1–3 ), and a new natural product, dihydroponicidin ( 4 ), together with five known ones were isolated from the aerial parts of Isodon rosthornii . The structures were determined by means of extensive spectroscopic analysis. All diterpenoids isolated were evaluated for their cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines, and compounds 5 and 7 showed significant inhibitory effects on all cell lines.
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titleIsorosthornins A-C, new ent -kaurane diterpenoids from Isodon rosthornii
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abstractThree new ent -kauranoids, isorosthornins A-C ( 1–3 ), and a new natural product, dihydroponicidin ( 4 ), together with five known ones were isolated from the aerial parts of Isodon rosthornii . The structures were determined by means of extensive spectroscopic analysis. All diterpenoids isolated were evaluated for their cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines, and compounds 5 and 7 showed significant inhibitory effects on all cell lines.
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