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Expression and clinical significance of FXYD3 in endometrial cancer

FXYD3 expression is upregulated in numerous cancer cell types. The present study compared the FXDY3 expression in normal endometrium, premalignant lesion and endometrial cancer tissue samples, and investigated the correlation between FXDY3 expression and clinicopathological features. FXYD3 expressio... Full description

Journal Title: Oncology Letters 2014, Vol.8(2), pp.517-522
Main Author: Li, Yifei
Other Authors: Zhang, Xia , Xu, Shuwen , Ge, Jing , Liu, Jing , Li, Lin , Fang, Guiying , Meng, Yali , Zhang, Hongzhen , Sun, Xiao-Feng
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 1792-1074 ; ISSN: 1792-1074 ; DOI: 10.3892/ol.2014.2170
Link: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-109366
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recordid: swepuboai:DiVA.org:liu-109366
title: Expression and clinical significance of FXYD3 in endometrial cancer
format: Article
creator:
  • Li, Yifei
  • Zhang, Xia
  • Xu, Shuwen
  • Ge, Jing
  • Liu, Jing
  • Li, Lin
  • Fang, Guiying
  • Meng, Yali
  • Zhang, Hongzhen
  • Sun, Xiao-Feng
subjects:
  • Medical And Health Sciences
  • Clinical Medicine
  • Medicin Och Hälsovetenskap
  • Klinisk Medicin
  • Fxyd3
  • Endometrial Hyperplasia
  • Endometrial Neoplasm
  • Immunohistochemistry
ispartof: Oncology Letters, 2014, Vol.8(2), pp.517-522
description: FXYD3 expression is upregulated in numerous cancer cell types. The present study compared the FXDY3 expression in normal endometrium, premalignant lesion and endometrial cancer tissue samples, and investigated the correlation between FXDY3 expression and clinicopathological features. FXYD3 expression was analyzed by streptavidin-peroxidase immunohistochemistry in 21 normal endometrial tissue samples, 18 atypical endometrial hyperplasia samples and 50 tissues obtained from patients diagnosed with endometrial cancer. The percentage of FXYD3-positive cell expression in the normal endometrium, atypical hyperplasia and endometrial cancer tissues samples was 0, 22, and 26%, respectively. The differences between the atypical hyperplasia and endometrial cancer groups were statistically significant when compared with the normal group (P=0.007 and P=0.037, respectively). There was no significant difference between the atypical hyperplasia and endometrial cancer groups. The percentage of FXYD3-positive...
language: eng
source:
identifier: ISSN: 1792-1074 ; ISSN: 1792-1074 ; DOI: 10.3892/ol.2014.2170
fulltext: fulltext
issn:
  • 1792-1074
  • 17921074
url: Link


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titleExpression and clinical significance of FXYD3 in endometrial cancer
creatorLi, Yifei ; Zhang, Xia ; Xu, Shuwen ; Ge, Jing ; Liu, Jing ; Li, Lin ; Fang, Guiying ; Meng, Yali ; Zhang, Hongzhen ; Sun, Xiao-Feng
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subjectMedical And Health Sciences ; Clinical Medicine ; Medicin Och Hälsovetenskap ; Klinisk Medicin ; Fxyd3; Endometrial Hyperplasia; Endometrial Neoplasm; Immunohistochemistry
descriptionFXYD3 expression is upregulated in numerous cancer cell types. The present study compared the FXDY3 expression in normal endometrium, premalignant lesion and endometrial cancer tissue samples, and investigated the correlation between FXDY3 expression and clinicopathological features. FXYD3 expression was analyzed by streptavidin-peroxidase immunohistochemistry in 21 normal endometrial tissue samples, 18 atypical endometrial hyperplasia samples and 50 tissues obtained from patients diagnosed with endometrial cancer. The percentage of FXYD3-positive cell expression in the normal endometrium, atypical hyperplasia and endometrial cancer tissues samples was 0, 22, and 26%, respectively. The differences between the atypical hyperplasia and endometrial cancer groups were statistically significant when compared with the normal group (P=0.007 and P=0.037, respectively). There was no significant difference between the atypical hyperplasia and endometrial cancer groups. The percentage of FXYD3-positive...
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titleExpression and clinical significance of FXYD3 in endometrial cancer
descriptionFXYD3 expression is upregulated in numerous cancer cell types. The present study compared the FXDY3 expression in normal endometrium, premalignant lesion and endometrial cancer tissue samples, and investigated the correlation between FXDY3 expression and clinicopathological features. FXYD3 expression was analyzed by streptavidin-peroxidase immunohistochemistry in 21 normal endometrial tissue samples, 18 atypical endometrial hyperplasia samples and 50 tissues obtained from patients diagnosed with endometrial cancer. The percentage of FXYD3-positive cell expression in the normal endometrium, atypical hyperplasia and endometrial cancer tissues samples was 0, 22, and 26%, respectively. The differences between the atypical hyperplasia and endometrial cancer groups were statistically significant when compared with the normal group (P=0.007 and P=0.037, respectively). There was no significant difference between the atypical hyperplasia and endometrial cancer groups. The percentage of FXYD3-positive...
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titleExpression and clinical significance of FXYD3 in endometrial cancer
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abstractFXYD3 expression is upregulated in numerous cancer cell types. The present study compared the FXDY3 expression in normal endometrium, premalignant lesion and endometrial cancer tissue samples, and investigated the correlation between FXDY3 expression and clinicopathological features. FXYD3 expression was analyzed by streptavidin-peroxidase immunohistochemistry in 21 normal endometrial tissue samples, 18 atypical endometrial hyperplasia samples and 50 tissues obtained from patients diagnosed with endometrial cancer. The percentage of FXYD3-positive cell expression in the normal endometrium, atypical hyperplasia and endometrial cancer tissues samples was 0, 22, and 26%, respectively. The differences between the atypical hyperplasia and endometrial cancer groups were statistically significant when compared with the normal group (P=0.007 and P=0.037, respectively). There was no significant difference between the atypical hyperplasia and endometrial cancer groups. The percentage of FXYD3-positive...
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pages517-522
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