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Potentiometric propranolol-selective sensor based on molecularly imprinted polymer

A novel potentiometric sensor based on molecularly imprinted polymer (MIP) for propranolol, an adrenergic-blocking drug, was designed. The influence of molecularly imprinted polymer particle content and sodium tetraphenylborate additives in polyvinylchloride membrane was shown. The electrodes show n... Full description

Journal Title: Analytical and Bioanalytical Chemistry 2013, Vol.405(1), pp.287-295
Main Author: Gurtova, O.
Other Authors: Ye, Lei , Chmilenko, F.
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 1618-2642 ; ISSN: 1618-2642 ; PMID: 23104313 ; DOI: 10.1007/s00216-012-6493-6
Link: https://lup.lub.lu.se/record/3480990
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recordid: swepuboai:lup.lub.lu.se:d6b2b379-1d5a-4e61-86c0-b4ba9bfd3152
title: Potentiometric propranolol-selective sensor based on molecularly imprinted polymer
format: Article
creator:
  • Gurtova, O.
  • Ye, Lei
  • Chmilenko, F.
subjects:
  • Molecular Imprinted Polymer
  • Propranolol
  • Potentiometric Sensor
  • Nanoparticles
  • Anaprilin
  • Naturvetenskap
  • Kemi
  • Analytisk Kemi
  • Natural Sciences
  • Chemical Sciences
  • Analytical Chemistry
ispartof: Analytical and Bioanalytical Chemistry, 2013, Vol.405(1), pp.287-295
description: A novel potentiometric sensor based on molecularly imprinted polymer (MIP) for propranolol, an adrenergic-blocking drug, was designed. The influence of molecularly imprinted polymer particle content and sodium tetraphenylborate additives in polyvinylchloride membrane was shown. The electrodes show near-Nernstian responses down to 10(-4)-10(-5) M propranolol concentration. The potentiometric response of MIP-based sensor for propranolol in mixed nonaqueous medium was shown at first. Sensor selectivity relative to various inorganic cations, atenolol and metoprolol, was reported. Direct potentiometry was used to determine propranolol in aqueous modeling solutions and pharmaceutical preparations with good results.
language: eng
source:
identifier: ISSN: 1618-2642 ; ISSN: 1618-2642 ; PMID: 23104313 ; DOI: 10.1007/s00216-012-6493-6
fulltext: fulltext
issn:
  • 1618-2642
  • 16182642
url: Link


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titlePotentiometric propranolol-selective sensor based on molecularly imprinted polymer
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subjectMolecular Imprinted Polymer ; Propranolol ; Potentiometric Sensor ; Nanoparticles ; Anaprilin ; Naturvetenskap ; Kemi ; Analytisk Kemi ; Natural Sciences ; Chemical Sciences ; Analytical Chemistry
descriptionA novel potentiometric sensor based on molecularly imprinted polymer (MIP) for propranolol, an adrenergic-blocking drug, was designed. The influence of molecularly imprinted polymer particle content and sodium tetraphenylborate additives in polyvinylchloride membrane was shown. The electrodes show near-Nernstian responses down to 10(-4)-10(-5) M propranolol concentration. The potentiometric response of MIP-based sensor for propranolol in mixed nonaqueous medium was shown at first. Sensor selectivity relative to various inorganic cations, atenolol and metoprolol, was reported. Direct potentiometry was used to determine propranolol in aqueous modeling solutions and pharmaceutical preparations with good results.
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abstractA novel potentiometric sensor based on molecularly imprinted polymer (MIP) for propranolol, an adrenergic-blocking drug, was designed. The influence of molecularly imprinted polymer particle content and sodium tetraphenylborate additives in polyvinylchloride membrane was shown. The electrodes show near-Nernstian responses down to 10(-4)-10(-5) M propranolol concentration. The potentiometric response of MIP-based sensor for propranolol in mixed nonaqueous medium was shown at first. Sensor selectivity relative to various inorganic cations, atenolol and metoprolol, was reported. Direct potentiometry was used to determine propranolol in aqueous modeling solutions and pharmaceutical preparations with good results.
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