schliessen

Filtern

 

Bibliotheken

Global, regional, and national burden of neurological disorders, 1990-2016:: a systematic analysis for the Global Burden of Disease Study 2016

Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and na... Full description

Journal Title: The Lancet. Neurology 2019, Vol.18(5), pp.459-480
Main Author: Culpepper,, Wj
Other Authors: Dorsey, Ray , Feigin, Valery , Alam, Tahiya , Nichols, Emma , Bannick, Marlena , Beghi, Ettore , Blake, Natacha , Culpepper, Will , Petzold, Max , Dorsey, Er , Ärnlöv, Johan , Vos, T , Elbaz, A , Ellenbogen, Rg , Fisher, Jl , Fitzmaurice, C , Giussani, G , Glennie, L , James, Sl , Johnson, Co , Kassebaum, Nj , Logroscino, G , Marin, B , Mountjoy-Venning, Wc , Nguyen, M , Ofori-Asenso, R , Patel, Ap , Piccininni, M , Roth, Ga , Steiner, Tj , Stovner, Lj , Szoeke, Cei , Theadom, A , Vollset, Se , Wallin, Mt , Wright, C , Zunt, Jr , Abbasi, N , Abd-Allah, F , Abdelalim, A , Abdollahpour, I , Aboyans, V , Abraha, Hn , Acharya, D , Adamu, Aa , Adebayo, Om , Adeoye, Am , Adsuar, Jc , Afarideh, M , Agrawal, S , Ahmadi, A , Ahmed, Mb , Aichour, An , Aichour, I , Aichour, Mte , Akinyemi, Ro , Akseer, N , Al-Eyadhy, A , Salman, Ra , Alahdab, F , Alene, Ka , Aljunid, Sm , Altirkawi, K , Alvis-Guzman, N , Anber, Nh , Antonio, Cat , Arabloo, J , Aremu, O , Arnlov, J , Asayesh, H , Asghar, Rj , Atalay, Ht , Awasthi, A , Quintanilla, Bpa , Ayuk, Tb , Badawi, A , Banach, M , Banoub, Jam , Barboza, Ma , Barker-Collo, Sl , Barnighausen, Tw , Baune, Bt , Bedi, N , Behzadifar, M , Behzadifar, M , Bejot, Y , Bekele, Bb , Belachew, Ab , Bennett, Da , Bensenor, Im , Berhane, A , Beuran, M , Bhattacharyya, K , Bhutta, Za , Biadgo, B , Bijani, A , Bililign, N , Bin Sayeed, Ms , Blazes, Ck , Brayne, C , Butt, Za , Campos-Nonato, Ir , Cantu-Brito, C , Car, M , Cardenas, R , Carrero, Jj , Carvalho, F , Castaneda-Orjuela, Ca , Castro, F , Catala-Lopez, F , Cerin, E , Chaiah, Y , Chang, Jc , Chatziralli, I , Chiang, Ppc , Christensen, H , Christopher, Dj , Cooper, C , Cortesi, Pa , Costa, Vm , Criqui, Mh , Crowe, Cs , Damasceno, Aam , Daryani, A , De La Cruz-Gongora, V , De La Hoz, Fp , De Leo, D , Degefa, Mg , Demoz, Gt , Deribe, K , Dharmaratne, Sd , Diaz, D , Dinberu, Mt , Djalalinia, S , Doku, Dt , Dubey, M , Dubljanin, E , Duken, Ee , Edvardsson, D , El-Khatib, Z , Endres, M , Endries, Ay , Eskandarieh, S , Esteghamati, A , Esteghamati, S , Farhadi, F , Faro, A , Farzadfar, F , Farzaei, Mh , Fatima, B , Fereshtehnejad, Sm , Fernandes, E , Feyissa, Gt , Filip, I , Fischer, F , Fukumoto, T , Ganji, M , Gankpe, Fg , Garcia-Gordillo, Ma , Gebre, Ak , Gebremichael, Tg , Gelaw, Bk , Geleijnse, Jm , Geremew, D , Gezae, Ke , Ghasemi-Kasman, M , Gidey, My , Gill, Ps , Gill, Tk , Gnedovskaya, Ev , Goulart, Ac , Grada, A , Grosso, G , Guo, Ym , Gupta, R , Gupta, R , Haagsma, Ja , Hagos, Tb , Haj-Mirzaian, A , Haj-Mirzaian, A , Hamadeh, Rr , Hamidi, S , Hankey, Gj , Hao, Y , Haro, Jm , Hassankhani, H , Hassen, Hy , Havmoeller, R , Hay, Si , Hegazy, Mi , Heidari, B , Henok, A , Heydarpour, F , Hoang, Cl , Hole, Mk , Rad, Eh , Hosseini, Sm , Hu, Gq , Igumbor, Eu , Ilesanmi, Os , Irvani, Ssn , Islam, Sms , Jakovljevic, M , Javanbakht, M , Jha, Rp , Jobanputra, Yb , Jonas, Jb , Jozwiak, Jj , Jurisson, M , Kahsay, A , Kalani, R , Kalkonde, Y , Kamil, Ta , Kanchan, T , Karami, M , Karch, A , Karimi, N , Kasaeian, A , Kassa, Td , Kassa, Zy , Kaul, A , Kefale, At , Keiyoro, Pn , Khader, Ys , Khafaie, Ma , Khalil, Ia , Khan, Ea , Khang, Yh , Khazaie, H , Kiadaliri, Aa , Kiirithio, Dn , Kim, As , Kim, D , Kim, Ye , Kim, Yj , Kisa, A , Kokubo, Y , Koyanagi, A , Krishnamurthi, Rv , Defo, Bk , Bicer, Bk , Kumar, M , Lacey, B , Lafranconi, A , Lansingh, Vc , Latifi, A , Leshargie, Ct , Li, Ss , Liao, Y
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 1474-4465 ; ISSN: 1474-4465 ; PMID: 30879893 ; DOI: 10.1016/S1474-4422(18)30499-X
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: swepuboai:prod.swepub.kib.ki.se:140702154
title: Global, regional, and national burden of neurological disorders, 1990-2016:: a systematic analysis for the Global Burden of Disease Study 2016
format: Article
creator:
  • Culpepper,, Wj
  • Dorsey, Ray
  • Feigin, Valery
  • Alam, Tahiya
  • Nichols, Emma
  • Bannick, Marlena
  • Beghi, Ettore
  • Blake, Natacha
  • Culpepper, Will
  • Petzold, Max
  • Dorsey, Er
  • Ärnlöv, Johan
  • Vos, T
  • Elbaz, A
  • Ellenbogen, Rg
  • Fisher, Jl
  • Fitzmaurice, C
  • Giussani, G
  • Glennie, L
  • James, Sl
  • Johnson, Co
  • Kassebaum, Nj
  • Logroscino, G
  • Marin, B
  • Mountjoy-Venning, Wc
  • Nguyen, M
  • Ofori-Asenso, R
  • Patel, Ap
  • Piccininni, M
  • Roth, Ga
  • Steiner, Tj
  • Stovner, Lj
  • Szoeke, Cei
  • Theadom, A
  • Vollset, Se
  • Wallin, Mt
  • Wright, C
  • Zunt, Jr
  • Abbasi, N
  • Abd-Allah, F
  • Abdelalim, A
  • Abdollahpour, I
  • Aboyans, V
  • Abraha, Hn
  • Acharya, D
  • Adamu, Aa
  • Adebayo, Om
  • Adeoye, Am
  • Adsuar, Jc
  • Afarideh, M
  • Agrawal, S
  • Ahmadi, A
  • Ahmed, Mb
  • Aichour, An
  • Aichour, I
  • Aichour, Mte
  • Akinyemi, Ro
  • Akseer, N
  • Al-Eyadhy, A
  • Salman, Ra
  • Alahdab, F
  • Alene, Ka
  • Aljunid, Sm
  • Altirkawi, K
  • Alvis-Guzman, N
  • Anber, Nh
  • Antonio, Cat
  • Arabloo, J
  • Aremu, O
  • Arnlov, J
  • Asayesh, H
  • Asghar, Rj
  • Atalay, Ht
  • Awasthi, A
  • Quintanilla, Bpa
  • Ayuk, Tb
  • Badawi, A
  • Banach, M
  • Banoub, Jam
  • Barboza, Ma
  • Barker-Collo, Sl
  • Barnighausen, Tw
  • Baune, Bt
  • Bedi, N
  • Behzadifar, M
  • Behzadifar, M
  • Bejot, Y
  • Bekele, Bb
  • Belachew, Ab
  • Bennett, Da
  • Bensenor, Im
  • Berhane, A
  • Beuran, M
  • Bhattacharyya, K
  • Bhutta, Za
  • Biadgo, B
  • Bijani, A
  • Bililign, N
  • Bin Sayeed, Ms
  • Blazes, Ck
  • Brayne, C
  • Butt, Za
  • Campos-Nonato, Ir
  • Cantu-Brito, C
  • Car, M
  • Cardenas, R
  • Carrero, Jj
  • Carvalho, F
  • Castaneda-Orjuela, Ca
  • Castro, F
  • Catala-Lopez, F
  • Cerin, E
  • Chaiah, Y
  • Chang, Jc
  • Chatziralli, I
  • Chiang, Ppc
  • Christensen, H
  • Christopher, Dj
  • Cooper, C
  • Cortesi, Pa
  • Costa, Vm
  • Criqui, Mh
  • Crowe, Cs
  • Damasceno, Aam
  • Daryani, A
  • De La Cruz-Gongora, V
  • De La Hoz, Fp
  • De Leo, D
  • Degefa, Mg
  • Demoz, Gt
  • Deribe, K
  • Dharmaratne, Sd
  • Diaz, D
  • Dinberu, Mt
  • Djalalinia, S
  • Doku, Dt
  • Dubey, M
  • Dubljanin, E
  • Duken, Ee
  • Edvardsson, D
  • El-Khatib, Z
  • Endres, M
  • Endries, Ay
  • Eskandarieh, S
  • Esteghamati, A
  • Esteghamati, S
  • Farhadi, F
  • Faro, A
  • Farzadfar, F
  • Farzaei, Mh
  • Fatima, B
  • Fereshtehnejad, Sm
  • Fernandes, E
  • Feyissa, Gt
  • Filip, I
  • Fischer, F
  • Fukumoto, T
  • Ganji, M
  • Gankpe, Fg
  • Garcia-Gordillo, Ma
  • Gebre, Ak
  • Gebremichael, Tg
  • Gelaw, Bk
  • Geleijnse, Jm
  • Geremew, D
  • Gezae, Ke
  • Ghasemi-Kasman, M
  • Gidey, My
  • Gill, Ps
  • Gill, Tk
  • Gnedovskaya, Ev
  • Goulart, Ac
  • Grada, A
  • Grosso, G
  • Guo, Ym
  • Gupta, R
  • Gupta, R
  • Haagsma, Ja
  • Hagos, Tb
  • Haj-Mirzaian, A
  • Haj-Mirzaian, A
  • Hamadeh, Rr
  • Hamidi, S
  • Hankey, Gj
  • Hao, Y
  • Haro, Jm
  • Hassankhani, H
  • Hassen, Hy
  • Havmoeller, R
  • Hay, Si
  • Hegazy, Mi
  • Heidari, B
  • Henok, A
  • Heydarpour, F
  • Hoang, Cl
  • Hole, Mk
  • Rad, Eh
  • Hosseini, Sm
  • Hu, Gq
  • Igumbor, Eu
  • Ilesanmi, Os
  • Irvani, Ssn
  • Islam, Sms
  • Jakovljevic, M
  • Javanbakht, M
  • Jha, Rp
  • Jobanputra, Yb
  • Jonas, Jb
  • Jozwiak, Jj
  • Jurisson, M
  • Kahsay, A
  • Kalani, R
  • Kalkonde, Y
  • Kamil, Ta
  • Kanchan, T
  • Karami, M
  • Karch, A
  • Karimi, N
  • Kasaeian, A
  • Kassa, Td
  • Kassa, Zy
  • Kaul, A
  • Kefale, At
  • Keiyoro, Pn
  • Khader, Ys
  • Khafaie, Ma
  • Khalil, Ia
  • Khan, Ea
  • Khang, Yh
  • Khazaie, H
  • Kiadaliri, Aa
  • Kiirithio, Dn
  • Kim, As
  • Kim, D
  • Kim, Ye
  • Kim, Yj
  • Kisa, A
  • Kokubo, Y
  • Koyanagi, A
  • Krishnamurthi, Rv
  • Defo, Bk
  • Bicer, Bk
  • Kumar, M
  • Lacey, B
  • Lafranconi, A
  • Lansingh, Vc
  • Latifi, A
  • Leshargie, Ct
  • Li, Ss
  • Liao, Y
subjects:
  • Hälsovetenskaper
  • Health Sciences
  • Medical And Health Sciences
  • Clinical Medicine
  • Medicin Och Hälsovetenskap
  • Klinisk Medicin
  • Health And Welfare
  • Hälsa Och Välfärd
ispartof: The Lancet. Neurology, 2019, Vol.18(5), pp.459-480
description: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders.We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer's disease and other dementias, Parkinson's disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016. DisMod-MR 2.1, a Bayesian meta-regression tool, was the main method of estimation of prevalence and incidence, and the Cause of Death Ensemble model (CODEm) was used for mortality estimation. We quantified the contribution of 84 risks and combinations of risk to the disease estimates for the 15 neurological disorder categories using the GBD comparative risk assessment approach.Globally, in 2016, neurological disorders were the leading cause of DALYs (276 million [95% UI 247-308]) and second leading cause of deaths (9·0 million [8·8-9·4]). The absolute number of deaths and DALYs from all neurological disorders combined increased (deaths by 39% [34-44] and DALYs by 15% [9-21]) whereas their age-standardised rates decreased (deaths by 28% [26-30] and DALYs by 27% [24-31]) between 1990 and 2016. The only neurological disorders that had a decrease in rates and absolute numbers of deaths and DALYs were tetanus, meningitis, and encephalitis. The four largest contributors of neurological DALYs were stroke (42·2% [38·6-46·1]), migraine (16·3% [11·7-20·8]), Alzheimer's and other dementias (10·4% [9·0-12·1]), and meningitis (7·9% [6·6-10·4]). For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05-1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7. The 84 risks quantified in GBD explain less than 10% of neurological disorder DALY burden
language: eng
source:
identifier: ISSN: 1474-4465 ; ISSN: 1474-4465 ; PMID: 30879893 ; DOI: 10.1016/S1474-4422(18)30499-X
fulltext: fulltext_linktorsrc
issn:
  • 1474-4465
  • 14744465
url: Link


@attributes
ID257492776
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordidoai:prod.swepub.kib.ki.se:140702154
sourceidswepub
recordidTN_swepuboai:prod.swepub.kib.ki.se:140702154
sourcesystemOther
pqid2207083391
galeid581987909
display
typearticle
titleGlobal, regional, and national burden of neurological disorders, 1990-2016:: a systematic analysis for the Global Burden of Disease Study 2016
creatorCulpepper,, Wj ; Dorsey, Ray ; Feigin, Valery ; Alam, Tahiya ; Nichols, Emma ; Bannick, Marlena ; Beghi, Ettore ; Blake, Natacha ; Culpepper, Will ; Petzold, Max ; Dorsey, Er ; Ärnlöv, Johan ; Vos, T ; Elbaz, A ; Ellenbogen, Rg ; Fisher, Jl ; Fitzmaurice, C ; Giussani, G ; Glennie, L ; James, Sl ; Johnson, Co ; Kassebaum, Nj ; Logroscino, G ; Marin, B ; Mountjoy-Venning, Wc ; Nguyen, M ; Ofori-Asenso, R ; Patel, Ap ; Piccininni, M ; Roth, Ga ; Steiner, Tj ; Stovner, Lj ; Szoeke, Cei ; Theadom, A ; Vollset, Se ; Wallin, Mt ; Wright, C ; Zunt, Jr ; Abbasi, N ; Abd-Allah, F ; Abdelalim, A ; Abdollahpour, I ; Aboyans, V ; Abraha, Hn ; Acharya, D ; Adamu, Aa ; Adebayo, Om ; Adeoye, Am ; Adsuar, Jc ; Afarideh, M ; Agrawal, S ; Ahmadi, A ; Ahmed, Mb ; Aichour, An ; Aichour, I ; Aichour, Mte ; Akinyemi, Ro ; Akseer, N ; Al-Eyadhy, A ; Salman, Ra ; Alahdab, F ; Alene, Ka ; Aljunid, Sm ; Altirkawi, K ; Alvis-Guzman, N ; Anber, Nh ; Antonio, Cat ; Arabloo, J ; Aremu, O ; Arnlov, J ; Asayesh, H ; Asghar, Rj ; Atalay, Ht ; Awasthi, A ; Quintanilla, Bpa ; Ayuk, Tb ; Badawi, A ; Banach, M ; Banoub, Jam ; Barboza, Ma ; Barker-Collo, Sl ; Barnighausen, Tw ; Baune, Bt ; Bedi, N ; Behzadifar, M ; Behzadifar, M ; Bejot, Y ; Bekele, Bb ; Belachew, Ab ; Bennett, Da ; Bensenor, Im ; Berhane, A ; Beuran, M ; Bhattacharyya, K ; Bhutta, Za ; Biadgo, B ; Bijani, A ; Bililign, N ; Bin Sayeed, Ms ; Blazes, Ck ; Brayne, C ; Butt, Za ; Campos-Nonato, Ir ; Cantu-Brito, C ; Car, M ; Cardenas, R ; Carrero, Jj ; Carvalho, F ; Castaneda-Orjuela, Ca ; Castro, F ; Catala-Lopez, F ; Cerin, E ; Chaiah, Y ; Chang, Jc ; Chatziralli, I ; Chiang, Ppc ; Christensen, H ; Christopher, Dj ; Cooper, C ; Cortesi, Pa ; Costa, Vm ; Criqui, Mh ; Crowe, Cs ; Damasceno, Aam ; Daryani, A ; De La Cruz-Gongora, V ; De La Hoz, Fp ; De Leo, D ; Degefa, Mg ; Demoz, Gt ; Deribe, K ; Dharmaratne, Sd ; Diaz, D ; Dinberu, Mt ; Djalalinia, S ; Doku, Dt ; Dubey, M ; Dubljanin, E ; Duken, Ee ; Edvardsson, D ; El-Khatib, Z ; Endres, M ; Endries, Ay ; Eskandarieh, S ; Esteghamati, A ; Esteghamati, S ; Farhadi, F ; Faro, A ; Farzadfar, F ; Farzaei, Mh ; Fatima, B ; Fereshtehnejad, Sm ; Fernandes, E ; Feyissa, Gt ; Filip, I ; Fischer, F ; Fukumoto, T ; Ganji, M ; Gankpe, Fg ; Garcia-Gordillo, Ma ; Gebre, Ak ; Gebremichael, Tg ; Gelaw, Bk ; Geleijnse, Jm ; Geremew, D ; Gezae, Ke ; Ghasemi-Kasman, M ; Gidey, My ; Gill, Ps ; Gill, Tk ; Gnedovskaya, Ev ; Goulart, Ac ; Grada, A ; Grosso, G ; Guo, Ym ; Gupta, R ; Gupta, R ; Haagsma, Ja ; Hagos, Tb ; Haj-Mirzaian, A ; Haj-Mirzaian, A ; Hamadeh, Rr ; Hamidi, S ; Hankey, Gj ; Hao, Y ; Haro, Jm ; Hassankhani, H ; Hassen, Hy ; Havmoeller, R ; Hay, Si ; Hegazy, Mi ; Heidari, B ; Henok, A ; Heydarpour, F ; Hoang, Cl ; Hole, Mk ; Rad, Eh ; Hosseini, Sm ; Hu, Gq ; Igumbor, Eu ; Ilesanmi, Os ; Irvani, Ssn ; Islam, Sms ; Jakovljevic, M ; Javanbakht, M ; Jha, Rp ; Jobanputra, Yb ; Jonas, Jb ; Jozwiak, Jj ; Jurisson, M ; Kahsay, A ; Kalani, R ; Kalkonde, Y ; Kamil, Ta ; Kanchan, T ; Karami, M ; Karch, A ; Karimi, N ; Kasaeian, A ; Kassa, Td ; Kassa, Zy ; Kaul, A ; Kefale, At ; Keiyoro, Pn ; Khader, Ys ; Khafaie, Ma ; Khalil, Ia ; Khan, Ea ; Khang, Yh ; Khazaie, H ; Kiadaliri, Aa ; Kiirithio, Dn ; Kim, As ; Kim, D ; Kim, Ye ; Kim, Yj ; Kisa, A ; Kokubo, Y ; Koyanagi, A ; Krishnamurthi, Rv ; Defo, Bk ; Bicer, Bk ; Kumar, M ; Lacey, B ; Lafranconi, A ; Lansingh, Vc ; Latifi, A ; Leshargie, Ct ; Li, Ss ; Liao, Y
ispartofThe Lancet. Neurology, 2019, Vol.18(5), pp.459-480
identifier
subjectHälsovetenskaper ; Health Sciences ; Medical And Health Sciences ; Clinical Medicine ; Medicin Och Hälsovetenskap ; Klinisk Medicin ; Health And Welfare ; Hälsa Och Välfärd
descriptionNeurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders.We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer's disease and other dementias, Parkinson's disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016. DisMod-MR 2.1, a Bayesian meta-regression tool, was the main method of estimation of prevalence and incidence, and the Cause of Death Ensemble model (CODEm) was used for mortality estimation. We quantified the contribution of 84 risks and combinations of risk to the disease estimates for the 15 neurological disorder categories using the GBD comparative risk assessment approach.Globally, in 2016, neurological disorders were the leading cause of DALYs (276 million [95% UI 247-308]) and second leading cause of deaths (9·0 million [8·8-9·4]). The absolute number of deaths and DALYs from all neurological disorders combined increased (deaths by 39% [34-44] and DALYs by 15% [9-21]) whereas their age-standardised rates decreased (deaths by 28% [26-30] and DALYs by 27% [24-31]) between 1990 and 2016. The only neurological disorders that had a decrease in rates and absolute numbers of deaths and DALYs were tetanus, meningitis, and encephalitis. The four largest contributors of neurological DALYs were stroke (42·2% [38·6-46·1]), migraine (16·3% [11·7-20·8]), Alzheimer's and other dementias (10·4% [9·0-12·1]), and meningitis (7·9% [6·6-10·4]). For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05-1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7. The 84 risks quantified in GBD explain less than 10% of neurological disorder DALY burdens, except stroke, for which 88·8% (86·5-90·9) of DALYs are attributable to risk factors, and to a lesser extent Alzheimer's disease and other dementias (22·3% [11·8-35·1] of DALYs are risk attributable) and idiopathic epilepsy (14·1% [10·8-17·5] of DALYs are risk attributable).Globally, the burden of neurological disorders, as measured by the absolute number of DALYs, continues to increase. As populations are growing and ageing, and the prevalence of major disabling neurological disorders steeply increases with age, governments will face increasing demand for treatment, rehabilitation, and support services for neurological disorders. The scarcity of established modifiable risks for most of the neurological burden demonstrates that new knowledge is required to develop effective prevention and treatment strategies.Bill & Melinda Gates Foundation.
languageeng
source
version21
oafree_for_read
lds50peer_reviewed
links
openurl$$Topenurl_article
backlink
0$$Uhttps://gup.ub.gu.se/publication/279566$$EView_source_record
1$$Uhttp://urn.kb.se/resolve?urn=urn:nbn:se:du-29933$$EView_source_record
2$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:140702154$$EView_source_record
linktorsrc$$Uhttps://doi.org/10.1016/S1474-4422(18)30499-X$$EView_full_record
openurlfulltext$$Topenurlfull_article
search
creatorcontrib
0Culpepper,, Wj
1Dorsey, Ray
2Feigin, Valery
3Alam, Tahiya
4Nichols, Emma
5Bannick, Marlena
6Beghi, Ettore
7Blake, Natacha
8Culpepper, Will
9Petzold, Max
10Dorsey, Er
11Ärnlöv, Johan
12Vos, T
13Elbaz, A
14Ellenbogen, Rg
15Fisher, Jl
16Fitzmaurice, C
17Giussani, G
18Glennie, L
19James, Sl
20Johnson, Co
21Kassebaum, Nj
22Logroscino, G
23Marin, B
24Mountjoy-Venning, Wc
25Nguyen, M
26Ofori-Asenso, R
27Patel, Ap
28Piccininni, M
29Roth, Ga
30Steiner, Tj
31Stovner, Lj
32Szoeke, Cei
33Theadom, A
34Vollset, Se
35Wallin, Mt
36Wright, C
37Zunt, Jr
38Abbasi, N
39Abd-Allah, F
40Abdelalim, A
41Abdollahpour, I
42Aboyans, V
43Abraha, Hn
44Acharya, D
45Adamu, Aa
46Adebayo, Om
47Adeoye, Am
48Adsuar, Jc
49Afarideh, M
50Agrawal, S
51Ahmadi, A
52Ahmed, Mb
53Aichour, An
54Aichour, I
55Aichour, Mte
56Akinyemi, Ro
57Akseer, N
58Al-Eyadhy, A
59Salman, Ra
60Alahdab, F
61Alene, Ka
62Aljunid, Sm
63Altirkawi, K
64Alvis-Guzman, N
65Anber, Nh
66Antonio, Cat
67Arabloo, J
68Aremu, O
69Arnlov, J
70Asayesh, H
71Asghar, Rj
72Atalay, Ht
73Awasthi, A
74Quintanilla, Bpa
75Ayuk, Tb
76Badawi, A
77Banach, M
78Banoub, Jam
79Barboza, Ma
80Barker-Collo, Sl
81Barnighausen, Tw
82Baune, Bt
83Bedi, N
84Behzadifar, M
85Bejot, Y
86Bekele, Bb
87Belachew, Ab
88Bennett, Da
89Bensenor, Im
90Berhane, A
91Beuran, M
92Bhattacharyya, K
93Bhutta, Za
94Biadgo, B
95Bijani, A
96Bililign, N
97Bin Sayeed, Ms
98Blazes, Ck
99Brayne, C
100...
titleGlobal, regional, and national burden of neurological disorders, 1990-2016:: a systematic analysis for the Global Burden of Disease Study 2016
descriptionNeurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders.We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer's disease and other dementias, Parkinson's disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016. DisMod-MR 2.1, a Bayesian meta-regression tool, was the main method of estimation of prevalence and incidence, and the Cause of Death Ensemble model (CODEm) was used for mortality estimation. We quantified the contribution of 84 risks and combinations of risk to the disease estimates for the 15 neurological disorder categories using the GBD comparative risk assessment approach.Globally, in 2016, neurological disorders were the leading cause of DALYs (276 million [95% UI 247-308]) and second leading cause of deaths (9·0 million [8·8-9·4]). The absolute number of deaths and DALYs from all neurological disorders combined increased (deaths by 39% [34-44] and DALYs by 15% [9-21]) whereas their age-standardised rates decreased (deaths by 28% [26-30] and DALYs by 27% [24-31]) between 1990 and 2016. The only neurological disorders that had a decrease in rates and absolute numbers of deaths and DALYs were tetanus, meningitis, and encephalitis. The four largest contributors of neurological DALYs were stroke (42·2% [38·6-46·1]), migraine (16·3% [11·7-20·8]), Alzheimer's and other dementias (10·4% [9·0-12·1]), and meningitis (7·9% [6·6-10·4]). For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05-1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7. The 84 risks quantified in GBD explain less than 10% of neurological disorder DALY burdens, except stroke, for which 88·8% (86·5-90·9) of DALYs are attributable to risk factors, and to a lesser extent Alzheimer's disease and other dementias (22·3% [11·8-35·1] of DALYs are risk attributable) and idiopathic epilepsy (14·1% [10·8-17·5] of DALYs are risk attributable).Globally, the burden of neurological disorders, as measured by the absolute number of DALYs, continues to increase. As populations are growing and ageing, and the prevalence of major disabling neurological disorders steeply increases with age, governments will face increasing demand for treatment, rehabilitation, and support services for neurological disorders. The scarcity of established modifiable risks for most of the neurological burden demonstrates that new knowledge is required to develop effective prevention and treatment strategies.Bill & Melinda Gates Foundation.
subject
0Hälsovetenskaper
1Health Sciences
2Medical And Health Sciences
3Clinical Medicine
4Medicin Och Hälsovetenskap
5Klinisk Medicin
6Health And Welfare
7Hälsa Och Välfärd
general
0English
110.1016/S1474-4422(18)30499-X
2SwePub (National Library of Sweden)
330879893
sourceidswepub
recordidswepuboai:prod.swepub.kib.ki.se:140702154
issn
01474-4465
114744465
rsrctypearticle
creationdate2019
addtitleThe Lancet. Neurology
searchscope
0swepub_oa
1swepub_oa_article
scope
0swepub_oa
1swepub_oa_article
lsr30VSR-Enriched:[orcidid, pqid, pages, galeid, issn]
sort
titleGlobal, regional, and national burden of neurological disorders, 1990-2016:: a systematic analysis for the Global Burden of Disease Study 2016
authorCulpepper,, Wj ; Dorsey, Ray ; Feigin, Valery ; Alam, Tahiya ; Nichols, Emma ; Bannick, Marlena ; Beghi, Ettore ; Blake, Natacha ; Culpepper, Will ; Petzold, Max ; Dorsey, Er ; Ärnlöv, Johan ; Vos, T ; Elbaz, A ; Ellenbogen, Rg ; Fisher, Jl ; Fitzmaurice, C ; Giussani, G ; Glennie, L ; James, Sl ; Johnson, Co ; Kassebaum, Nj ; Logroscino, G ; Marin, B ; Mountjoy-Venning, Wc ; Nguyen, M ; Ofori-Asenso, R ; Patel, Ap ; Piccininni, M ; Roth, Ga ; Steiner, Tj ; Stovner, Lj ; Szoeke, Cei ; Theadom, A ; Vollset, Se ; Wallin, Mt ; Wright, C ; Zunt, Jr ; Abbasi, N ; Abd-Allah, F ; Abdelalim, A ; Abdollahpour, I ; Aboyans, V ; Abraha, Hn ; Acharya, D ; Adamu, Aa ; Adebayo, Om ; Adeoye, Am ; Adsuar, Jc ; Afarideh, M ; Agrawal, S ; Ahmadi, A ; Ahmed, Mb ; Aichour, An ; Aichour, I ; Aichour, Mte ; Akinyemi, Ro ; Akseer, N ; Al-Eyadhy, A ; Salman, Ra ; Alahdab, F ; Alene, Ka ; Aljunid, Sm ; Altirkawi, K ; Alvis-Guzman, N ; Anber, Nh ; Antonio, Cat ; Arabloo, J ; Aremu, O ; Arnlov, J ; Asayesh, H ; Asghar, Rj ; Atalay, Ht ; Awasthi, A ; Quintanilla, Bpa ; Ayuk, Tb ; Badawi, A ; Banach, M ; Banoub, Jam ; Barboza, Ma ; Barker-Collo, Sl ; Barnighausen, Tw ; Baune, Bt ; Bedi, N ; Behzadifar, M ; Behzadifar, M ; Bejot, Y ; Bekele, Bb ; Belachew, Ab ; Bennett, Da ; Bensenor, Im ; Berhane, A ; Beuran, M ; Bhattacharyya, K ; Bhutta, Za ; Biadgo, B ; Bijani, A ; Bililign, N ; Bin Sayeed, Ms ; Blazes, Ck ; Brayne, C ; Butt, Za ; Campos-Nonato, Ir ; Cantu-Brito, C ; Car, M ; Cardenas, R ; Carrero, Jj ; Carvalho, F ; Castaneda-Orjuela, Ca ; Castro, F ; Catala-Lopez, F ; Cerin, E ; Chaiah, Y ; Chang, Jc ; Chatziralli, I ; Chiang, Ppc ; Christensen, H ; Christopher, Dj ; Cooper, C ; Cortesi, Pa ; Costa, Vm ; Criqui, Mh ; Crowe, Cs ; Damasceno, Aam ; Daryani, A ; De La Cruz-Gongora, V ; De La Hoz, Fp ; De Leo, D ; Degefa, Mg ; Demoz, Gt ; Deribe, K ; Dharmaratne, Sd ; Diaz, D ; Dinberu, Mt ; Djalalinia, S ; Doku, Dt ; Dubey, M ; Dubljanin, E ; Duken, Ee ; Edvardsson, D ; El-Khatib, Z ; Endres, M ; Endries, Ay ; Eskandarieh, S ; Esteghamati, A ; Esteghamati, S ; Farhadi, F ; Faro, A ; Farzadfar, F ; Farzaei, Mh ; Fatima, B ; Fereshtehnejad, Sm ; Fernandes, E ; Feyissa, Gt ; Filip, I ; Fischer, F ; Fukumoto, T ; Ganji, M ; Gankpe, Fg ; Garcia-Gordillo, Ma ; Gebre, Ak ; Gebremichael, Tg ; Gelaw, Bk ; Geleijnse, Jm ; Geremew, D ; Gezae, Ke ; Ghasemi-Kasman, M ; Gidey, My ; Gill, Ps ; Gill, Tk ; Gnedovskaya, Ev ; Goulart, Ac ; Grada, A ; Grosso, G ; Guo, Ym ; Gupta, R ; Gupta, R ; Haagsma, Ja ; Hagos, Tb ; Haj-Mirzaian, A ; Haj-Mirzaian, A ; Hamadeh, Rr ; Hamidi, S ; Hankey, Gj ; Hao, Y ; Haro, Jm ; Hassankhani, H ; Hassen, Hy ; Havmoeller, R ; Hay, Si ; Hegazy, Mi ; Heidari, B ; Henok, A ; Heydarpour, F ; Hoang, Cl ; Hole, Mk ; Rad, Eh ; Hosseini, Sm ; Hu, Gq ; Igumbor, Eu ; Ilesanmi, Os ; Irvani, Ssn ; Islam, Sms ; Jakovljevic, M ; Javanbakht, M ; Jha, Rp ; Jobanputra, Yb ; Jonas, Jb ; Jozwiak, Jj ; Jurisson, M ; Kahsay, A ; Kalani, R ; Kalkonde, Y ; Kamil, Ta ; Kanchan, T ; Karami, M ; Karch, A ; Karimi, N ; Kasaeian, A ; Kassa, Td ; Kassa, Zy ; Kaul, A ; Kefale, At ; Keiyoro, Pn ; Khader, Ys ; Khafaie, Ma ; Khalil, Ia ; Khan, Ea ; Khang, Yh ; Khazaie, H ; Kiadaliri, Aa ; Kiirithio, Dn ; Kim, As ; Kim, D ; Kim, Ye ; Kim, Yj ; Kisa, A ; Kokubo, Y ; Koyanagi, A ; Krishnamurthi, Rv ; Defo, Bk ; Bicer, Bk ; Kumar, M ; Lacey, B ; Lafranconi, A ; Lansingh, Vc ; Latifi, A ; Leshargie, Ct ; Li, Ss ; Liao, Y
creationdate20190000
facets
frbrgroupid6607789371643028379
frbrtype5
newrecords20190605
languageeng
creationdate2019
topic
0Hälsovetenskaper
1Health Sciences
2Medical And Health Sciences
3Clinical Medicine
4Medicin Och Hälsovetenskap
5Klinisk Medicin
6Health And Welfare
7Hälsa Och Välfärd
collectionSwePub (National Library of Sweden)- Free access
prefilterarticles
rsrctypearticles
creatorcontrib
0Culpepper,, WJ
1Dorsey, Ray
2Feigin, Valery
3Alam, Tahiya
4Nichols, Emma
5Bannick, Marlena
6Beghi, Ettore
7Blake, Natacha
8Culpepper, Will
9Petzold, Max
10Dorsey, ER
11Ärnlöv, Johan
12Vos, T
13Elbaz, A
14Ellenbogen, RG
15Fisher, JL
16Fitzmaurice, C
17Giussani, G
18Glennie, L
19James, SL
20Johnson, CO
21Kassebaum, NJ
22Logroscino, G
23Marin, B
24Mountjoy-Venning, WC
25Nguyen, M
26Ofori-Asenso, R
27Patel, AP
28Piccininni, M
29Roth, GA
30Steiner, TJ
31Stovner, LJ
32Szoeke, CEI
33Theadom, A
34Vollset, SE
35Wallin, MT
36Wright, C
37Zunt, JR
38Abbasi, N
39Abd-Allah, F
40Abdelalim, A
41Abdollahpour, I
42Aboyans, V
43Abraha, HN
44Acharya, D
45Adamu, AA
46Adebayo, OM
47Adeoye, AM
48Adsuar, JC
49Afarideh, M
50Agrawal, S
51Ahmadi, A
52Ahmed, MB
53Aichour, AN
54Aichour, I
55Aichour, MTE
56Akinyemi, RO
57Akseer, N
58Al-Eyadhy, A
59Salman, RA
60Alahdab, F
61Alene, KA
62Aljunid, SM
63Altirkawi, K
64Alvis-Guzman, N
65Anber, NH
66Antonio, CAT
67Arabloo, J
68Aremu, O
69Arnlov, J
70Asayesh, H
71Asghar, RJ
72Atalay, HT
73Awasthi, A
74Quintanilla, BPA
75Ayuk, TB
76Badawi, A
77Banach, M
78Banoub, JAM
79Barboza, MA
80Barker-Collo, SL
81Barnighausen, TW
82Baune, BT
83Bedi, N
84Behzadifar, M
85Bejot, Y
86Bekele, BB
87Belachew, AB
88Bennett, DA
89Bensenor, IM
90Berhane, A
91Beuran, M
92Bhattacharyya, K
93Bhutta, ZA
94Biadgo, B
95Bijani, A
96Bililign, N
97Bin Sayeed, MS
98Blazes, CK
99Brayne, C
100...
jtitleLancet. Neurology
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext_linktorsrc
addata
aulastCulpepper,
aufirstWJ
au
0Culpepper,, WJ
1Dorsey, Ray
2Feigin, Valery
3Alam, Tahiya
4Nichols, Emma
5Bannick, Marlena
6Beghi, Ettore
7Blake, Natacha
8Culpepper, Will
9Petzold, Max
10Dorsey, ER
11Ärnlöv, Johan
12Vos, T
13Elbaz, A
14Ellenbogen, RG
15Fisher, JL
16Fitzmaurice, C
17Giussani, G
18Glennie, L
19James, SL
20Johnson, CO
21Kassebaum, NJ
22Logroscino, G
23Marin, B
24Mountjoy-Venning, WC
25Nguyen, M
26Ofori-Asenso, R
27Patel, AP
28Piccininni, M
29Roth, GA
30Steiner, TJ
31Stovner, LJ
32Szoeke, CEI
33Theadom, A
34Vollset, SE
35Wallin, MT
36Wright, C
37Zunt, JR
38Abbasi, N
39Abd-Allah, F
40Abdelalim, A
41Abdollahpour, I
42Aboyans, V
43Abraha, HN
44Acharya, D
45Adamu, AA
46Adebayo, OM
47Adeoye, AM
48Adsuar, JC
49Afarideh, M
50Agrawal, S
51Ahmadi, A
52Ahmed, MB
53Aichour, AN
54Aichour, I
55Aichour, MTE
56Akinyemi, RO
57Akseer, N
58Al-Eyadhy, A
59Salman, RA
60Alahdab, F
61Alene, KA
62Aljunid, SM
63Altirkawi, K
64Alvis-Guzman, N
65Anber, NH
66Antonio, CAT
67Arabloo, J
68Aremu, O
69Arnlov, J
70Asayesh, H
71Asghar, RJ
72Atalay, HT
73Awasthi, A
74Quintanilla, BPA
75Ayuk, TB
76Badawi, A
77Banach, M
78Banoub, JAM
79Barboza, MA
80Barker-Collo, SL
81Barnighausen, TW
82Baune, BT
83Bedi, N
84Behzadifar, M
85Bejot, Y
86Bekele, BB
87Belachew, AB
88Bennett, DA
89Bensenor, IM
90Berhane, A
91Beuran, M
92Bhattacharyya, K
93Bhutta, ZA
94Biadgo, B
95Bijani, A
96Bililign, N
97Bin Sayeed, MS
98Blazes, CK
99Brayne, C
100...
atitleGlobal, regional, and national burden of neurological disorders, 1990-2016:: a systematic analysis for the Global Burden of Disease Study 2016
jtitleLancet. Neurology
date2019
risdate2019
volume18
issue5
spage459
epage480
issn
01474-4465
114744422
genrearticle
ristypeJOUR
abstractNeurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders.We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer's disease and other dementias, Parkinson's disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016. DisMod-MR 2.1, a Bayesian meta-regression tool, was the main method of estimation of prevalence and incidence, and the Cause of Death Ensemble model (CODEm) was used for mortality estimation. We quantified the contribution of 84 risks and combinations of risk to the disease estimates for the 15 neurological disorder categories using the GBD comparative risk assessment approach.Globally, in 2016, neurological disorders were the leading cause of DALYs (276 million [95% UI 247-308]) and second leading cause of deaths (9·0 million [8·8-9·4]). The absolute number of deaths and DALYs from all neurological disorders combined increased (deaths by 39% [34-44] and DALYs by 15% [9-21]) whereas their age-standardised rates decreased (deaths by 28% [26-30] and DALYs by 27% [24-31]) between 1990 and 2016. The only neurological disorders that had a decrease in rates and absolute numbers of deaths and DALYs were tetanus, meningitis, and encephalitis. The four largest contributors of neurological DALYs were stroke (42·2% [38·6-46·1]), migraine (16·3% [11·7-20·8]), Alzheimer's and other dementias (10·4% [9·0-12·1]), and meningitis (7·9% [6·6-10·4]). For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05-1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7. The 84 risks quantified in GBD explain less than 10% of neurological disorder DALY burdens, except stroke, for which 88·8% (86·5-90·9) of DALYs are attributable to risk factors, and to a lesser extent Alzheimer's disease and other dementias (22·3% [11·8-35·1] of DALYs are risk attributable) and idiopathic epilepsy (14·1% [10·8-17·5] of DALYs are risk attributable).Globally, the burden of neurological disorders, as measured by the absolute number of DALYs, continues to increase. As populations are growing and ageing, and the prevalence of major disabling neurological disorders steeply increases with age, governments will face increasing demand for treatment, rehabilitation, and support services for neurological disorders. The scarcity of established modifiable risks for most of the neurological burden demonstrates that new knowledge is required to develop effective prevention and treatment strategies.Bill & Melinda Gates Foundation.
doi10.1016/S1474-4422(18)30499-X
pmid30879893
orcidid0000-0002-6933-4637
pages459-480
oafree_for_read