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Mesoporous Silica‐Coated Gold Nanorods as a Light‐Mediated Multifunctional Theranostic Platform for Cancer Treatment

(Au@SiO) are developed as a promising and versatile theranostic platform for cancer treatment. Intracellular localization of Au@SiO is visualized through two‐photon imaging. With doxorubicin hydrochloride loaded, Au@SiO–DOX show two light‐mediated therapeutic modes: low power density laser‐triggered... Full description

Journal Title: Advanced Materials 15 March 2012, Vol.24(11), pp.1418-1423
Main Author: Zhang, Zhenjiang
Other Authors: Wang, Liming , Wang, Jing , Jiang, Xiumei , Li, Xiaohui , Hu, Zhijian , Ji, Yinglu , Wu, Xiaochun , Chen, Chunying
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0935-9648 ; E-ISSN: 1521-4095 ; DOI: 10.1002/adma.201104714
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recordid: wj10.1002/adma.201104714
title: Mesoporous Silica‐Coated Gold Nanorods as a Light‐Mediated Multifunctional Theranostic Platform for Cancer Treatment
format: Article
creator:
  • Zhang, Zhenjiang
  • Wang, Liming
  • Wang, Jing
  • Jiang, Xiumei
  • Li, Xiaohui
  • Hu, Zhijian
  • Ji, Yinglu
  • Wu, Xiaochun
  • Chen, Chunying
subjects:
  • Silica‐Coated Gold Nanorods
  • Theranostics
  • Light‐Controlled Drug Release
  • Chemotherapy
  • Hyperthermia
ispartof: Advanced Materials, 15 March 2012, Vol.24(11), pp.1418-1423
description: (Au@SiO) are developed as a promising and versatile theranostic platform for cancer treatment. Intracellular localization of Au@SiO is visualized through two‐photon imaging. With doxorubicin hydrochloride loaded, Au@SiO–DOX show two light‐mediated therapeutic modes: low power density laser‐triggered drug release for chemotherapy, and high power density laser‐induced hyperthermia, which suggest the potential for in‐vivo applications.
language: eng
source:
identifier: ISSN: 0935-9648 ; E-ISSN: 1521-4095 ; DOI: 10.1002/adma.201104714
fulltext: fulltext
issn:
  • 0935-9648
  • 09359648
  • 1521-4095
  • 15214095
url: Link


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titleMesoporous Silica‐Coated Gold Nanorods as a Light‐Mediated Multifunctional Theranostic Platform for Cancer Treatment
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subjectSilica‐Coated Gold Nanorods ; Theranostics ; Light‐Controlled Drug Release ; Chemotherapy ; Hyperthermia
description(Au@SiO) are developed as a promising and versatile theranostic platform for cancer treatment. Intracellular localization of Au@SiO is visualized through two‐photon imaging. With doxorubicin hydrochloride loaded, Au@SiO–DOX show two light‐mediated therapeutic modes: low power density laser‐triggered drug release for chemotherapy, and high power density laser‐induced hyperthermia, which suggest the potential for in‐vivo applications.
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titleMesoporous Silica‐Coated Gold Nanorods as a Light‐Mediated Multifunctional Theranostic Platform for Cancer Treatment
description(Au@SiO) are developed as a promising and versatile theranostic platform for cancer treatment. Intracellular localization of Au@SiO is visualized through two‐photon imaging. With doxorubicin hydrochloride loaded, Au@SiO–DOX show two light‐mediated therapeutic modes: low power density laser‐triggered drug release for chemotherapy, and high power density laser‐induced hyperthermia, which suggest the potential for in‐vivo applications.
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abstract(Au@SiO) are developed as a promising and versatile theranostic platform for cancer treatment. Intracellular localization of Au@SiO is visualized through two‐photon imaging. With doxorubicin hydrochloride loaded, Au@SiO–DOX show two light‐mediated therapeutic modes: low power density laser‐triggered drug release for chemotherapy, and high power density laser‐induced hyperthermia, which suggest the potential for in‐vivo applications.
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pubWILEY‐VCH Verlag
doi10.1002/adma.201104714
pages1418-1423
date2012-03-15