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On‐Demand Drug Release System for In Vivo Cancer Treatment through Self‐Assembled Magnetic Nanoparticles

: Magnetothermally responsive drug‐encapsulated supramolecular nanoparticles for on‐demand drug release in vivo have been developed. The remote application of an alternative magnetic field heats the magnetic particles that effectively trigger the release of the drug. An acute drug concentration can... Full description

Journal Title: Angewandte Chemie International Edition 15 April 2013, Vol.52(16), pp.4384-4388
Main Author: Lee, Jae‐Hyun
Other Authors: Chen, Kuan‐Ju , Noh, Seung‐Hyun , Garcia, Mitch André , Wang, Hao , Lin, Wei‐Yu , Jeong, Heeyeong , Kong, Brian Junoh , Stout, David B. , Cheon, Jinwoo , Tseng, Hsian‐Rong
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 1433-7851 ; E-ISSN: 1521-3773 ; DOI: 10.1002/anie.201207721
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recordid: wj10.1002/anie.201207721
title: On‐Demand Drug Release System for In Vivo Cancer Treatment through Self‐Assembled Magnetic Nanoparticles
format: Article
creator:
  • Lee, Jae‐Hyun
  • Chen, Kuan‐Ju
  • Noh, Seung‐Hyun
  • Garcia, Mitch André
  • Wang, Hao
  • Lin, Wei‐Yu
  • Jeong, Heeyeong
  • Kong, Brian Junoh
  • Stout, David B.
  • Cheon, Jinwoo
  • Tseng, Hsian‐Rong
subjects:
  • Drug Delivery
  • Magnetic Heat Induction
  • Magnetic Nanoparticles
  • Molecular Imaging
  • Supramolecular Chemistry
ispartof: Angewandte Chemie International Edition, 15 April 2013, Vol.52(16), pp.4384-4388
description: : Magnetothermally responsive drug‐encapsulated supramolecular nanoparticles for on‐demand drug release in vivo have been developed. The remote application of an alternative magnetic field heats the magnetic particles that effectively trigger the release of the drug. An acute drug concentration can be delivered to the tumor in vivo, resulting in an improved therapeutic outcome.
language: eng
source:
identifier: ISSN: 1433-7851 ; E-ISSN: 1521-3773 ; DOI: 10.1002/anie.201207721
fulltext: fulltext
issn:
  • 1433-7851
  • 14337851
  • 1521-3773
  • 15213773
url: Link


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titleOn‐Demand Drug Release System for In Vivo Cancer Treatment through Self‐Assembled Magnetic Nanoparticles
creatorLee, Jae‐Hyun ; Chen, Kuan‐Ju ; Noh, Seung‐Hyun ; Garcia, Mitch André ; Wang, Hao ; Lin, Wei‐Yu ; Jeong, Heeyeong ; Kong, Brian Junoh ; Stout, David B. ; Cheon, Jinwoo ; Tseng, Hsian‐Rong
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subjectDrug Delivery ; Magnetic Heat Induction ; Magnetic Nanoparticles ; Molecular Imaging ; Supramolecular Chemistry
description: Magnetothermally responsive drug‐encapsulated supramolecular nanoparticles for on‐demand drug release in vivo have been developed. The remote application of an alternative magnetic field heats the magnetic particles that effectively trigger the release of the drug. An acute drug concentration can be delivered to the tumor in vivo, resulting in an improved therapeutic outcome.
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titleOn‐Demand Drug Release System for In Vivo Cancer Treatment through Self‐Assembled Magnetic Nanoparticles
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authorLee, Jae‐Hyun ; Chen, Kuan‐Ju ; Noh, Seung‐Hyun ; Garcia, Mitch André ; Wang, Hao ; Lin, Wei‐Yu ; Jeong, Heeyeong ; Kong, Brian Junoh ; Stout, David B. ; Cheon, Jinwoo ; Tseng, Hsian‐Rong
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abstract: Magnetothermally responsive drug‐encapsulated supramolecular nanoparticles for on‐demand drug release in vivo have been developed. The remote application of an alternative magnetic field heats the magnetic particles that effectively trigger the release of the drug. An acute drug concentration can be delivered to the tumor in vivo, resulting in an improved therapeutic outcome.
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pages4384-4388
date2013-04-15