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Synthesis of Isoindolo[2,1‐ a ]quinazoline Derivatives in Ionic Liquid Catalyzed by Iodine

A mild, green, and facile method for the synthesis of 6,6‐dihydroisoindolo[2,1‐]quinazoline‐5,11‐dione derivatives is described in high yields using as green media. The method involves the reaction of 2‐aminobenzamides with 2‐formylbenzoic acid catalyzed by iodine and provides a new alkaloid library... Full description

Journal Title: Journal of Heterocyclic Chemistry May 2014, Vol.51(3), pp.630-634
Main Author: Lu, Lian
Other Authors: Yang, Ke , Zhang, Mei‐Mei , Wang, Xiang‐Shan
Format: Electronic Article Electronic Article
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ID: ISSN: 0022-152X ; E-ISSN: 1943-5193 ; DOI: 10.1002/jhet.1696
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recordid: wj10.1002/jhet.1696
title: Synthesis of Isoindolo[2,1‐ a ]quinazoline Derivatives in Ionic Liquid Catalyzed by Iodine
format: Article
creator:
  • Lu, Lian
  • Yang, Ke
  • Zhang, Mei‐Mei
  • Wang, Xiang‐Shan
subjects:
  • Ions
  • Solvents
ispartof: Journal of Heterocyclic Chemistry, May 2014, Vol.51(3), pp.630-634
description: A mild, green, and facile method for the synthesis of 6,6‐dihydroisoindolo[2,1‐]quinazoline‐5,11‐dione derivatives is described in high yields using as green media. The method involves the reaction of 2‐aminobenzamides with 2‐formylbenzoic acid catalyzed by iodine and provides a new alkaloid library with potential activity for biomedical screening.
language:
source:
identifier: ISSN: 0022-152X ; E-ISSN: 1943-5193 ; DOI: 10.1002/jhet.1696
fulltext: fulltext
issn:
  • 0022-152X
  • 0022152X
  • 1943-5193
  • 19435193
url: Link


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descriptionA mild, green, and facile method for the synthesis of 6,6‐dihydroisoindolo[2,1‐]quinazoline‐5,11‐dione derivatives is described in high yields using as green media. The method involves the reaction of 2‐aminobenzamides with 2‐formylbenzoic acid catalyzed by iodine and provides a new alkaloid library with potential activity for biomedical screening.
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titleSynthesis of Isoindolo[2,1‐ a ]quinazoline Derivatives in Ionic Liquid Catalyzed by Iodine
descriptionA mild, green, and facile method for the synthesis of 6,6‐dihydroisoindolo[2,1‐]quinazoline‐5,11‐dione derivatives is described in high yields using as green media. The method involves the reaction of 2‐aminobenzamides with 2‐formylbenzoic acid catalyzed by iodine and provides a new alkaloid library with potential activity for biomedical screening.
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abstractA mild, green, and facile method for the synthesis of 6,6‐dihydroisoindolo[2,1‐]quinazoline‐5,11‐dione derivatives is described in high yields using as green media. The method involves the reaction of 2‐aminobenzamides with 2‐formylbenzoic acid catalyzed by iodine and provides a new alkaloid library with potential activity for biomedical screening.
doi10.1002/jhet.1696
pages630-634
date2014-05