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Green Synthesis of Spiro[indoline‐3,4′‐pyrazolo[3,4‐b][1,6]naphthyridine]‐2,5′(1′H)‐diones Catalyzed by TsOH in Ionic Liquids

A three‐component reaction of isatin, 3‐methyl‐1‐phenyl‐1‐pyrazol‐5‐amine, and piperidine‐2,4‐dione was treated in catalyzed by TsOH and provided an efficient and green method for the synthesis of spiro[indoline‐3,4′‐pyrazolo[3, 4‐][1,6]naphthyridine]‐2,5′(1′)‐dione derivatives in high yields.... Full description

Journal Title: Journal of Heterocyclic Chemistry September 2016, Vol.53(5), pp.1578-1583
Main Author: Feng, Bin‐Bin
Other Authors: Jin, Rong‐Zhang , Zhang, Mei‐Mei , Wang, Xiang‐Shan
Format: Electronic Article Electronic Article
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ID: ISSN: 0022-152X ; E-ISSN: 1943-5193 ; DOI: 10.1002/jhet.2466
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recordid: wj10.1002/jhet.2466
title: Green Synthesis of Spiro[indoline‐3,4′‐pyrazolo[3,4‐b][1,6]naphthyridine]‐2,5′(1′H)‐diones Catalyzed by TsOH in Ionic Liquids
format: Article
creator:
  • Feng, Bin‐Bin
  • Jin, Rong‐Zhang
  • Zhang, Mei‐Mei
  • Wang, Xiang‐Shan
subjects:
  • Ions
  • Solvents
  • Liquids
ispartof: Journal of Heterocyclic Chemistry, September 2016, Vol.53(5), pp.1578-1583
description: A three‐component reaction of isatin, 3‐methyl‐1‐phenyl‐1‐pyrazol‐5‐amine, and piperidine‐2,4‐dione was treated in catalyzed by TsOH and provided an efficient and green method for the synthesis of spiro[indoline‐3,4′‐pyrazolo[3, 4‐][1,6]naphthyridine]‐2,5′(1′)‐dione derivatives in high yields.
language:
source:
identifier: ISSN: 0022-152X ; E-ISSN: 1943-5193 ; DOI: 10.1002/jhet.2466
fulltext: fulltext
issn:
  • 0022-152X
  • 0022152X
  • 1943-5193
  • 19435193
url: Link


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titleGreen Synthesis of Spiro[indoline‐3,4′‐pyrazolo[3,4‐b][1,6]naphthyridine]‐2,5′(1′H)‐diones Catalyzed by TsOH in Ionic Liquids
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descriptionA three‐component reaction of isatin, 3‐methyl‐1‐phenyl‐1‐pyrazol‐5‐amine, and piperidine‐2,4‐dione was treated in catalyzed by TsOH and provided an efficient and green method for the synthesis of spiro[indoline‐3,4′‐pyrazolo[3, 4‐][1,6]naphthyridine]‐2,5′(1′)‐dione derivatives in high yields.
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titleGreen Synthesis of Spiro[indoline‐3,4′‐pyrazolo[3,4‐b][1,6]naphthyridine]‐2,5′(1′H)‐diones Catalyzed by TsOH in Ionic Liquids
descriptionA three‐component reaction of isatin, 3‐methyl‐1‐phenyl‐1‐pyrazol‐5‐amine, and piperidine‐2,4‐dione was treated in catalyzed by TsOH and provided an efficient and green method for the synthesis of spiro[indoline‐3,4′‐pyrazolo[3, 4‐][1,6]naphthyridine]‐2,5′(1′)‐dione derivatives in high yields.
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titleGreen Synthesis of Spiro[indoline‐3,4′‐pyrazolo[3,4‐b][1,6]naphthyridine]‐2,5′(1′H)‐diones Catalyzed by TsOH in Ionic Liquids
authorFeng, Bin‐Bin ; Jin, Rong‐Zhang ; Zhang, Mei‐Mei ; Wang, Xiang‐Shan
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abstractA three‐component reaction of isatin, 3‐methyl‐1‐phenyl‐1‐pyrazol‐5‐amine, and piperidine‐2,4‐dione was treated in catalyzed by TsOH and provided an efficient and green method for the synthesis of spiro[indoline‐3,4′‐pyrazolo[3, 4‐][1,6]naphthyridine]‐2,5′(1′)‐dione derivatives in high yields.
doi10.1002/jhet.2466
pages1578-1583
date2016-09