schliessen

Filtern

 

Bibliotheken

Comorbid diseases of IgG4‐related sialadenitis in the head and neck region

To further recognize the comorbid diseases of immunoglobulin G4-related sialadenitis (IgG4-RS) in the head and neck region and to observe the response of these conditions to immunomodulatory therapy. Retrospective review. The symptoms of comorbid diseases and medical histories in 51 patients (24 men... Full description

Journal Title: Laryngoscope September 2015, Vol.125(9), pp.2113-2118
Main Author: Hong, Xia
Other Authors: Sun, Zhi‐Peng , Li, Wei , Chen, Yan , Gao, Yan , Su, Jia‐Zeng , Wang, Zhen , Cai, Zhi‐Gang , Li, Tong‐Tong , Zhang, Lei , Liu, Xiao‐Jing , Liu, Yan‐Ying , He, Jing , Li, Zhan‐Guo , Yu, Guang‐Yan
Format: Electronic Article Electronic Article
Language:
Subjects:
ID: ISSN: 0023-852X ; E-ISSN: 1531-4995 ; DOI: 10.1002/lary.25387
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: wj10.1002/lary.25387
title: Comorbid diseases of IgG4‐related sialadenitis in the head and neck region
format: Article
creator:
  • Hong, Xia
  • Sun, Zhi‐Peng
  • Li, Wei
  • Chen, Yan
  • Gao, Yan
  • Su, Jia‐Zeng
  • Wang, Zhen
  • Cai, Zhi‐Gang
  • Li, Tong‐Tong
  • Zhang, Lei
  • Liu, Xiao‐Jing
  • Liu, Yan‐Ying
  • He, Jing
  • Li, Zhan‐Guo
  • Yu, Guang‐Yan
subjects:
  • Igg4‐Related Sialadenitis
  • Comorbid Diseases
  • Head And Neck
  • Rhinosinusitis
  • Lymphadenopathy
  • Ocular Adnexa
  • Salivary Gland
ispartof: Laryngoscope, September 2015, Vol.125(9), pp.2113-2118
description: To further recognize the comorbid diseases of immunoglobulin G4-related sialadenitis (IgG4-RS) in the head and neck region and to observe the response of these conditions to immunomodulatory therapy. Retrospective review. The symptoms of comorbid diseases and medical histories in 51 patients (24 men, 27 women; median age, 55 years) diagnosed with IgG4-RS were analyzed. Thirty-six patients received immunomodulatory therapy and were followed up for 10.4 ± 5.9 months. Computed tomography (CT) examination was performed before and after therapy. Rhinosinusitis occurred in 58.8% patients, and manifested with the symptoms of nasal obstruction, nasal xerosis, and hyposmia. In addition, 43.1% patients had allergic rhinitis. Lymphadenopathy was identified in 74.5% patients. Lacrimal gland swelling occurred in 78.4% patients. Extraocular muscles, otologic organs, skin and superficial soft tissue, and cranial nerves were also involved. All of the lesions were relieved after immunomodulatory therapy. The Lund-Mackay scores decreased (9.6 ± 5.6 to 1.0 ± 2.2) according to CT analyses (P 
language:
source:
identifier: ISSN: 0023-852X ; E-ISSN: 1531-4995 ; DOI: 10.1002/lary.25387
fulltext: fulltext
issn:
  • 0023-852X
  • 0023852X
  • 1531-4995
  • 15314995
url: Link


@attributes
ID8017463
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordid10.1002/lary.25387
sourceidwj
recordidTN_wj10.1002/lary.25387
sourcesystemOther
pqid1705945445
galeid426254340
display
typearticle
titleComorbid diseases of IgG4‐related sialadenitis in the head and neck region
creatorHong, Xia ; Sun, Zhi‐Peng ; Li, Wei ; Chen, Yan ; Gao, Yan ; Su, Jia‐Zeng ; Wang, Zhen ; Cai, Zhi‐Gang ; Li, Tong‐Tong ; Zhang, Lei ; Liu, Xiao‐Jing ; Liu, Yan‐Ying ; He, Jing ; Li, Zhan‐Guo ; Yu, Guang‐Yan
ispartofLaryngoscope, September 2015, Vol.125(9), pp.2113-2118
identifier
subjectIgg4‐Related Sialadenitis ; Comorbid Diseases ; Head And Neck ; Rhinosinusitis ; Lymphadenopathy ; Ocular Adnexa ; Salivary Gland
source
descriptionTo further recognize the comorbid diseases of immunoglobulin G4-related sialadenitis (IgG4-RS) in the head and neck region and to observe the response of these conditions to immunomodulatory therapy. Retrospective review. The symptoms of comorbid diseases and medical histories in 51 patients (24 men, 27 women; median age, 55 years) diagnosed with IgG4-RS were analyzed. Thirty-six patients received immunomodulatory therapy and were followed up for 10.4 ± 5.9 months. Computed tomography (CT) examination was performed before and after therapy. Rhinosinusitis occurred in 58.8% patients, and manifested with the symptoms of nasal obstruction, nasal xerosis, and hyposmia. In addition, 43.1% patients had allergic rhinitis. Lymphadenopathy was identified in 74.5% patients. Lacrimal gland swelling occurred in 78.4% patients. Extraocular muscles, otologic organs, skin and superficial soft tissue, and cranial nerves were also involved. All of the lesions were relieved after immunomodulatory therapy. The Lund-Mackay scores decreased (9.6 ± 5.6 to 1.0 ± 2.2) according to CT analyses (P < .05). Mean CT volumes of the swollen lymph nodes and lacrimal glands decreased from 1.21 ± 0.61 cm(3) to 0.59 ± 0.35 cm(3) and from 2.25 ± 1.35 cm(3) to 0.70 ± 0.32 cm(3), respectively (P < .05) after treatment. IgG4-RS could potentially develop with involvement of ocular adnexa, sinonasal cavities, ears, lymph nodes, skin and superficial soft tissue, and cranial nerves in the head and neck region. Immunomodulatory therapy could be effective in controlling both the comorbid diseases of IgG4-RS and sialadenitis of the major salivary glands. 4.
version6
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
search
creatorcontrib
0Hong, Xia
1Sun, Zhi‐Peng
2Li, Wei
3Chen, Yan
4Gao, Yan
5Su, Jia‐Zeng
6Wang, Zhen
7Cai, Zhi‐Gang
8Li, Tong‐Tong
9Zhang, Lei
10Liu, Xiao‐Jing
11Liu, Yan‐Ying
12He, Jing
13Li, Zhan‐Guo
14Yu, Guang‐Yan
titleComorbid diseases of IgG4‐related sialadenitis in the head and neck region
subject
0Igg4‐Related Sialadenitis
1Comorbid Diseases
2Head And Neck
3Rhinosinusitis
4Lymphadenopathy
5Ocular Adnexa
6Salivary Gland
general
010.1002/lary.25387
1Wiley Online Library
sourceidwj
recordidwj10.1002/lary.25387
issn
00023-852X
10023852X
21531-4995
315314995
rsrctypearticle
creationdate2015
addtitleThe Laryngoscope
searchscope
0wj
1wiley
scope
0wj
1wiley
lsr30VSR-Enriched:[description, pqid, pages, galeid]
sort
titleComorbid diseases of IgG4‐related sialadenitis in the head and neck region
authorHong, Xia ; Sun, Zhi‐Peng ; Li, Wei ; Chen, Yan ; Gao, Yan ; Su, Jia‐Zeng ; Wang, Zhen ; Cai, Zhi‐Gang ; Li, Tong‐Tong ; Zhang, Lei ; Liu, Xiao‐Jing ; Liu, Yan‐Ying ; He, Jing ; Li, Zhan‐Guo ; Yu, Guang‐Yan
creationdate20150900
facets
frbrgroupid6947444727457902404
frbrtype5
creationdate2015
topic
0Igg4‐Related Sialadenitis
1Comorbid Diseases
2Head And Neck
3Rhinosinusitis
4Lymphadenopathy
5Ocular Adnexa
6Salivary Gland
collectionWiley Online Library
prefilterarticles
rsrctypearticles
creatorcontrib
0Hong, Xia
1Sun, Zhi‐Peng
2Li, Wei
3Chen, Yan
4Gao, Yan
5Su, Jia‐Zeng
6Wang, Zhen
7Cai, Zhi‐Gang
8Li, Tong‐Tong
9Zhang, Lei
10Liu, Xiao‐Jing
11Liu, Yan‐Ying
12He, Jing
13Li, Zhan‐Guo
14Yu, Guang‐Yan
jtitleLaryngoscope
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Hong
1Sun
2Li
3Chen
4Gao
5Su
6Wang
7Cai
8Zhang
9Liu
10He
11Yu
aufirst
0Xia
1Zhi‐Peng
2Wei
3Yan
4Jia‐Zeng
5Zhen
6Zhi‐Gang
7Tong‐Tong
8Lei
9Xiao‐Jing
10Yan‐Ying
11Jing
12Zhan‐Guo
13Guang‐Yan
au
0Hong, Xia
1Sun, Zhi‐Peng
2Li, Wei
3Chen, Yan
4Gao, Yan
5Su, Jia‐Zeng
6Wang, Zhen
7Cai, Zhi‐Gang
8Li, Tong‐Tong
9Zhang, Lei
10Liu, Xiao‐Jing
11Liu, Yan‐Ying
12He, Jing
13Li, Zhan‐Guo
14Yu, Guang‐Yan
atitleComorbid diseases of IgG4‐related sialadenitis in the head and neck region
jtitleLaryngoscope
risdate201509
volume125
issue9
spage2113
epage2118
issn0023-852X
eissn1531-4995
genrearticle
ristypeJOUR
doi10.1002/lary.25387
pages2113-2118
date2015-09