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Bone mineral density measurements in otosclerosis using dual‐energy X‐ray absorptiometry

Byline: S.B. Tonuk, S. Koybasi, Y.O. Bicer, S. Alkan Temel Objectives This study aims to evaluate patients with otosclerosis with respect to bone mineral density (BMD) at different regions of interest (ROI), using dual-energy X-ray absorptiometry (DXA). Design Cross-sectional controlled study. Setti... Full description

Journal Title: Clinical Otolaryngology April 2016, Vol.41(2), pp.149-153
Main Author: Tonuk, S. B.
Other Authors: Koybasi, S. , Bicer, Y. O. , Alkan Temel, S.
Format: Electronic Article Electronic Article
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ID: ISSN: 1749-4478 ; E-ISSN: 1749-4486 ; DOI: 10.1111/coa.12486
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recordid: wj10.1111/coa.12486
title: Bone mineral density measurements in otosclerosis using dual‐energy X‐ray absorptiometry
format: Article
creator:
  • Tonuk, S. B.
  • Koybasi, S.
  • Bicer, Y. O.
  • Alkan Temel, S.
subjects:
  • Osteoporosis – Measurement
  • Otosclerosis – Measurement
  • Bone Density – Measurement
ispartof: Clinical Otolaryngology, April 2016, Vol.41(2), pp.149-153
description: Byline: S.B. Tonuk, S. Koybasi, Y.O. Bicer, S. Alkan Temel Objectives This study aims to evaluate patients with otosclerosis with respect to bone mineral density (BMD) at different regions of interest (ROI), using dual-energy X-ray absorptiometry (DXA). Design Cross-sectional controlled study. Setting Tertiary referral hospital. Participants The patients with a definite diagnosis of otosclerosis confirmed intra-operatively were defined as the study group (n = 30). The control group consisted of volunteer, healthy subjects with normal hearing (n = 43). Main outcome measures Following an audiometric evaluation, a venous blood sample was obtained and a single BMD measurement using DXA was applied to each participant. Results The mean BMD, T and Z scores were higher in the otosclerosis group than in the control group in all the regions considered, but not significantly; only the L2-L3 lateral BMD and its T and Z scores were significant (P = 0.036, P = 0.029 and P = 0.036, respectively). Conclusion This study shows that the BMD does not decrease in the presence of otosclerosis despite its genetic and metabolic relevance with osteoporosis. Concerning the L2-L3 lateral BMD measurements, the BMD increased in otosclerosis.
language:
source:
identifier: ISSN: 1749-4478 ; E-ISSN: 1749-4486 ; DOI: 10.1111/coa.12486
fulltext: fulltext
issn:
  • 1749-4478
  • 17494478
  • 1749-4486
  • 17494486
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titleBone mineral density measurements in otosclerosis using dual‐energy X‐ray absorptiometry
creatorTonuk, S. B. ; Koybasi, S. ; Bicer, Y. O. ; Alkan Temel, S.
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subjectOsteoporosis – Measurement ; Otosclerosis – Measurement ; Bone Density – Measurement;
descriptionByline: S.B. Tonuk, S. Koybasi, Y.O. Bicer, S. Alkan Temel Objectives This study aims to evaluate patients with otosclerosis with respect to bone mineral density (BMD) at different regions of interest (ROI), using dual-energy X-ray absorptiometry (DXA). Design Cross-sectional controlled study. Setting Tertiary referral hospital. Participants The patients with a definite diagnosis of otosclerosis confirmed intra-operatively were defined as the study group (n = 30). The control group consisted of volunteer, healthy subjects with normal hearing (n = 43). Main outcome measures Following an audiometric evaluation, a venous blood sample was obtained and a single BMD measurement using DXA was applied to each participant. Results The mean BMD, T and Z scores were higher in the otosclerosis group than in the control group in all the regions considered, but not significantly; only the L2-L3 lateral BMD and its T and Z scores were significant (P = 0.036, P = 0.029 and P = 0.036, respectively). Conclusion This study shows that the BMD does not decrease in the presence of otosclerosis despite its genetic and metabolic relevance with osteoporosis. Concerning the L2-L3 lateral BMD measurements, the BMD increased in otosclerosis.
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