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Untersuchungen zur Verteilung von Dexamethason im Hundeauge nach lokaler Behandlung / vorgelegt von Tim Kaiser

The objective of this study was to determine the level of dexamethasone in different orbital structures after single local application into the conjunctival sac. In the scope of this dissertation, 30 dogs were available. Following a clinical examination they were divided equally into 3 groups. All d... Full description

PPN (Catalogue-ID): 378181041
Personen: Kaiser, Tim
Format: eBook eBook
Language: German
Published: 2003
Edition: [Electronic.ed]
Hochschule: Hannover, Tierärztl. Hochsch., Diss., 2003
Basisklassifikation: 46.14
Subjects:

Hund / Dexamethason / Arzneimittelverteilung / Lokaltherapie

Formangabe: Hochschulschrift
Physical Description: 127 S. = 1.000 Kb, Ill., graph. Darst.

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520 |a The objective of this study was to determine the level of dexamethasone in different orbital structures after single local application into the conjunctival sac. In the scope of this dissertation, 30 dogs were available. Following a clinical examination they were divided equally into 3 groups. All dogs were treated topically with a certain amount of 0,029% dexamethasone (0,2 ml ointment - equals 58 æg dexamethasone) eye ointment. The ointment was applied into the temporal canthus of the lower conjunctival sac. The animals were euthanatized in different intervals to the treatment (6, 11 and 16 hours). The Oculi bulbi were removed and from each eye, cornea, aqueous humor, iris, lens, vitreous humour, retina / choroid and nictitating membrane were subsequently isolated. The dexamethasone (DXM) concentrations were then evaluated via Radioimmunoassay from the above mentioned ... 
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