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Bioprocess engineering principles / Pauline M. Doran

The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revo... Full description

PPN (Catalogue-ID): 615789250
Personen: Doran, Pauline M. [VerfasserIn]
Format: eBook eBook
Language: English
Published: London [u.a.], Academic Press, 1995
Basisklassifikation: 58.30 Biotechnologie
42.03 Methoden und Techniken der Biologie
Subjects:

Biotechnologie

Biotechnology

Biochemical engineering

Industrial Chemistry

Biochemical engineering

Biotechnology

Biotechnologie

Notes: Includes bibliographical references and index
Physical Description: Online-Ressource (XIV, 439 S)
Link: Inhaltsverzeichnis
ISBN: 978-0-12-220855-3
0-12-220856-0
Sekundärausgabe Online-Ausg., 2009

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245 1 0 |a Bioprocess engineering principles  |h Elektronische Ressource  |c Pauline M. Doran 
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505 0 |a Front Cover; Bioprocess Engineering Principles; Copyright Page; Contents; Preface; Part 1: Introduction; Chapter 1. Bioprocess Development: An Interdisciplinary Challenge; 1.1 Steps in Bioprocess Development: A Typical New Product From Recombinant DNA; 1.2 A Quantitative Approach; Chapter 2. Introduction to Engineering Calculations; 2.1 Physical Variables, Dimensions and Units; 2.2 Units; 2.3 Force and Weight; 2.4 Measurement Conventions; 2.5 Standard Conditions and Ideal Gases; 2.6 Physical and Chemical Property Data; 2.7 Stoichiometry; 2.8 Summary of Chapter 2; Problems; References. 
505 0 |a Suggestions For Further ReadingChapter 3. Presentation and Analysis of Data; 3.1 Errors in Data and Calculations; 3.2 Presentation of Experimental Data; 3.3 Data Analysis; 3.4 Graph Paper With Logarithmic Coordinates; 3.5 General Procedures for Plotting Data; 3.6 Process Flow Diagrams; Problems; 3.7 Summary of Chapter 3; References; Suggestions for Further Reading; Part 2: Material and Energy Balances; Chapter 4. Material Balances; 4.1 Thermodynamic Preliminaries; 4.2 Law of Conservation of Mass Example; 4.3 Procedure For Material-Balance Calculations; 4.4 Material-Balance Worked Examples. 
505 0 |a 4.5 Material Balances With Recycle, By-Pass and Purge Streams4.6 Stoichiometry of Growth and Product Formation; 4.7 Summary of Chapter 4; Problems; References; Suggestions For Further Reading; Chapter 5. Energy Balances; 5.1 Basic Energy Concepts; 5.2 General Energy-Balance Equations; 5.3 Enthalpy Calculation Procedures; 5.4 Enthalpy Change in Non-Reactive Processes; 5.5 Steam Tables; 5.6 Procedure For Energy-Balance Calculations Without Reaction; 5.7 Energy-Balance Worked Examples Without Reaction; 5.8 Enthalpy Change Due to Reaction. 
505 0 |a 5.9 Heat of Reaction For Processes With Biomass Production5.10 Energy-Balance Equation For Cell Culture; 5.11 Fermentation Energy-Balance Worked Examples; 5.12 Summary of Chapter 5; Problems; References; Suggestions For Further Reading; Chapter 6. Unsteady-State Material and Energy Balances; 6.1 Unsteady-State Material-Balance Equations; 6.2 Unsteady-State Energy-Balance Equations; 6.3 Solving Differential Equations; 6.4 Solving Unsteady-State Mass Balances; 6.5 Solving Unsteady-State Energy Balances; 6.6 Summary of Chapter 6; Problems; References; Suggestions For Further Reading. 
505 0 |a Part 3: Physical ProcessesChapter 7. Fluid Flow and Mixing; 7.1 Classification of Fluids; 7.2 Fluids in Motion; 7.3 Viscosity; 7.4 Momentum Transfer; 7.5 Non-Newtonian Fluids; 7.6 Viscosity Measurement; 7.7 Rheological Properties of Fermentation Broths; 7.8 Factors Affecting Broth Viscosity; 7.9 Mixing; 7.10 Power Requirements for Mixing; 7.11 Scale-Up of Mixing Systems; 7.12 Improving Mixing in Fermenters; 7.13 Effect of Rheological Properties on Mixing; 7.14 Role of Shear in Stirred Fermenters; 7.15 Summary of Chapter 7; Problems; References; Suggestions For Further Reading. 
505 0 |a Chapter 8. Heat Transfer. 
520 |a The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists. This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems. * * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists * Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems * Comprehensive, single-authored * 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems * 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors * Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading * Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used * Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels. 
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