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The bigger the burn, the greater the stress /

Data characterizing the endocrine stress response to burn injury in children are sparse. We have measured the levels of the stress hormones arginine vasopressin, catecholamines-adrenaline, noradrenaline and dopamine-atrial natriuretic peptide and hormones of the renin-angiotensin-aldosterone system... Full description

PPN (Catalogue-ID): NLM092030114
Personen: Smith, A [VerfasserIn]
Barclay, C [VerfasserIn]
Quaba, A [VerfasserIn]
Sedowofia, K [VerfasserIn]
Stephen, R [VerfasserIn]
Thompson, M [VerfasserIn]
Watson, A [VerfasserIn]
McIntosh, N [VerfasserIn]
Format: Article Article
Language: English
Subjects:

Journal Article

Arginine Vasopressin / blood

Atrial Natriuretic Factor / blood

Burns / blood / *complications

Catecholamines / blood

Child

Child, Preschool

Chromatography, High Pressure Liquid

Humans

Infant

Radioimmunoassay

Renin-Angiotensin System / physiology

Severity of Illness Index

Stress, Physiological / blood / *etiology

Journal Article

Catecholamines / Arginine Vasopressin / 113-79-1 / Atrial Natriuretic Factor / 85637-73-6

Formangabe: Catecholamines, Arginine Vasopressin, 113-79-1, Atrial Natriuretic Factor, 85637-73-6
Notes: Date Completed 22.09.1997
Date Revised 21.11.2008
published: Print
Citation Status MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Enthaltenes Werk
Gesamtaufnahme:
in Burns : journal of the International Society for Burn Injuries , Vol. 23, No. 4 (1997), p. 291-4
ISSN: 1879-1409

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245 1 4 |a The bigger the burn, the greater the stress 
500 |a Date Completed 22.09.1997 
500 |a Date Revised 21.11.2008 
500 |a published: Print 
500 |a Citation Status MEDLINE 
500 |a Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine 
520 |a Data characterizing the endocrine stress response to burn injury in children are sparse. We have measured the levels of the stress hormones arginine vasopressin, catecholamines-adrenaline, noradrenaline and dopamine-atrial natriuretic peptide and hormones of the renin-angiotensin-aldosterone system in admission blood samples taken from 35 children admitted to the burns unit of the regional children's hospital. Hormone levels were compared with the size of burn injury. With the exception of adrenaline, there were significant positive correlations between vasopressin (r = 0.707, p < 0.0001), plasma renin activity (r = 0.721, P < 0.0001), angiotensin II (r = 0.512, P = 0.002), aldosterone (r = 0.620, P < 0.0001), noradrenaline (r = 0.430, P = 0.0189), dopamine (r = 0.627, P = 0.0024) and percentage burn surface area, and a negative correlation between atrial natriuretic peptide (r = 0.548, P = 0.0008) and burn surface area. It is concluded that the hormones which react to stress are very sensitive to burn injury in children, and that the magnitude of their response is closely related to the size of the burn surface area 
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700 1 |a Barclay, C  |e verfasserin  |4 aut 
700 1 |a Quaba, A  |e verfasserin  |4 aut 
700 1 |a Sedowofia, K  |e verfasserin  |4 aut 
700 1 |a Stephen, R  |e verfasserin  |4 aut 
700 1 |a Thompson, M  |e verfasserin  |4 aut 
700 1 |a Watson, A  |e verfasserin  |4 aut 
700 1 |a McIntosh, N  |e verfasserin  |4 aut 
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